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First-of-its-kind study reveals a new culprit in the formation of brain hemorrhages

A first-of-its-kind study led by the University of California, Irvine has revealed a new culprit in the formation of brain hemorrhages that does not involve injury to the blood vessels, as previously believed.

20 Nov 2023

Long-term monitoring of gene therapy patients crucial for safety, study says

Medical research has shown promising results regarding the potential of gene therapy to cure genetic conditions such as sickle cell disease and the findings of this study, published in Nature Medicine, offer important new insights into processes happening in the body after treatment.

16 Nov 2023

Researchers encourage flexible approach to blood transfusion decisions for heart attack patients with anemia

A National Institutes of Health-supported study found that the type of transfusion approach used to support adults who developed anemia after a heart attack did not make a significant difference in their likelihood of having another heart attack or dying within 30 days.

13 Nov 2023

Research investigates a novel strategy for inhibiting the spread of Vibrio cholerae

Karl Klose, director of The South Texas Center for Emerging Infectious Diseases (STCEID) and the Robert J. Kleberg, Jr. and Helen C. Kleberg College of Sciences Endowed Professor, coauthored a research article with Cameron Lloyd '23, a UTSA doctoral student who graduated in August with a Ph.D. in molecular microbiology and immunology under the guidance of Klose.

7 Nov 2023

Children need to be screened for vision problems as often as adults with sickle cell disease, study suggests

Sickle cell disease is a rare, inherited disorder in which the red blood cells become hard, sticky, and change shape, resembling the farm tool.

6 Nov 2023

How to optimize nuclei extraction & counting for single cell sequencing

In this interview, News Medical talks to DeNovix about the best way to prepare nuclei samples before single cell sequencing workflows and optimize nuclei extraction.

From DeNovix Inc. 1 Nov 2023

Sickle cell disease patients willing to accept high risks for gene therapy cure

Individuals living with severe sickle cell disease (SCD) are highly interested in new, potentially curative gene therapy treatments and are willing to accept associated risks for a chance at a cure, according to a study published today in Blood Advances.

31 Oct 2023

Malaria protein discovery opens new avenues for combating deadly infection

The discovery of a malaria protein that helps the parasite grow inside red blood cells and plays a key regulatory role in the parasite's immune evasion tactics could pave the way for new vaccines or therapeutics to combat the deadly infection.

26 Oct 2023

Atovaquone "chemical vaccine" for malaria could be more feasible than thought

Johns Hopkins researchers looking to develop a long-acting, injectable malaria preventive using atovaquone have shown in a new study that resistance may not be the challenge scientists thought it was, particularly when using atovaquone as a malaria preventive.

20 Oct 2023

For people with sickle cell disease, ERs can mean life-threatening waits

Heather Avant always dresses up when she goes to the emergency room.

17 Oct 2023

New clinical trial shows simple way to save thousands of units of blood every year

A world-first clinical trial published in JAMA could provide an easy way to save tens of thousands of units of blood every year in Canada and much more worldwide.

12 Oct 2023

FDA approves the use of sound waves to break down tumors in humans for liver treatment

The U.S. Food and Drug Administration has approved the use of sound waves to break down tumors—a technique called histotripsy—in humans for liver treatment.

9 Oct 2023

The cut-off for HbA1c-based diagnosis of diabetes may be too high in women

Researchers compare the distribution of glycated hemoglobin (HbA1c) levels in premenopausal women and men of the same age.

4 Oct 2023

New toolbox solves 50-year-old blood group mystery

Currently, a lot is known about which genes are responsible for our individual blood groups, however not much is understood about how and why the levels of the blood group molecules differ between one person and another.

29 Sep 2023

Pitt launches trial to test interventions for life-threatening bleeding in injured children

The No. 1 cause of death in children is trauma. There are an estimated 2,000 pediatric deaths from traumatic bleeding in the U.S. each year that are preventable with optimal care, yet there have been no large-scale clinical trials to guide the best way to resuscitate children with life-threatening bleeding from traumatic injury.

21 Sep 2023

New method detects microRNA targets at the level of single cells

MicroRNAs are small molecules that regulate gene activity by binding to and destroying RNAs produced by the genes.

21 Sep 2023

Mapping the human body one cell at a time: New study reveals the intricate relationship between cell size and count

A study published in PNAS provides a comprehensive look at the relationship between cell size and count across the human body, drawing from over 1,500 sources and identifying around 400 unique cell types. The research reveals an almost inverse relationship between cell size and count, offering a quantitative framework that could serve as a baseline for understanding cellular composition and function in various applications.

19 Sep 2023