Viral Disease News and Research

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UT Southwestern scientists discover mutation that causes X-linked reticulate pigmentary disorder

UT Southwestern Medical Center researchers have discovered a mutation that causes a rare systemic disorder known as X-linked reticulate pigmentary disorder (XLPDR) and, significantly, the unexpected cellular mechanism by which the mutation causes the disease.

29 Mar 2016

Antibodies given within one day of SHIV exposure can clear the virus

Scientists at the Oregon National Primate Research Center today revealed that infant rhesus macaques treated with antibodies within 24 hours of being exposed to SHIV, a chimeric simian virus that bears the HIV envelope protein, were completely cleared of the virus.

22 Mar 2016

Heart failure drug has unexpected ability to block herpesvirus infection

Today, there is only one class of antiviral medicines against herpesviruses - a family of viruses that cause mononucleosis, herpes, and shingles, among other illnesses - meaning options for treating these infections are limited. If viruses become resistant to these frontline treatments, a growing problem particularly in clinical settings, there are no alternative drugs to serve as backup.

15 Mar 2016

Researchers find new innate immunity pathway that protects mammals from viral oncogenesis

Building upon earlier research, investigators at UT Southwestern Medical Center and their collaborators have identified a new innate immunity pathway that protects mammals from viral oncogenesis, the process by which viruses cause normal cells to become cancerous.

14 Mar 2016

Mayo Clinic develops 'The ABCs of Influenza' flash cards

Influenza is a serious viral infection that causes illness, hospitalizations and thousands of deaths every year in the U.S. Mayo Clinic recommends getting a vaccine each year to prevent illness and protect the people around you.

9 Mar 2016

Bonn scientists identify immune factor partially responsible for chronic viral infection

Many viral diseases tend to become chronic - including infections with the HI virus. In persons affected, the immune response is not sufficient to eliminate the virus permanently.

8 Mar 2016

Rehabilitation-induced reorganization of damaged brain circuits responsible for functional recovery

Each year millions of people worldwide suffer from stroke, which can occur to anyone at any time. While some may recover completely, the majority of survivors will experience some form of impairment that requires a lengthy process toward partial or full recovery of functioning. Therefore, continuous improvement of rehabilitation methods is needed to ensure more positive long-term outcomes among survivors.

19 Feb 2016

Variations in Tie2 gene play significant role in patient responses to infections

Major infections such as influenza and bacterial sepsis kill millions of people each year, often resulting fro dangerous complications that impair the body's blood vessels. But the reasons why some patients experience these dramatic responses to infections -- and others don't -- have been unclear.

16 Feb 2016

Unlocking intrinsically disordered proteins: an interview with Peter Wright

I'm a professor in the Department of Integrative Structural and Computational Biology at The Scripps Research Institute. I have been performing NMR research on proteins for nearly 40 years.

From Bruker BioSpin Division 11 Feb 2016

Certain viral infections during pregnancy could cause behavioral changes in offspring

A study published in the journal Science found that activation in pregnant mice of a particular immune response, similar to what may occur with certain viral infections during pregnancy, alters the brain structure of the mouse offspring and causes behavioral changes, reminiscent of those observed in humans with autism spectrum disorder (ASD).

30 Jan 2016

Zepatier receives FDA approval for treatment of chronic HCV genotypes 1 and 4 infections

The U.S. Food and Drug Administration today approved Zepatier (elbasvir and grazoprevir) with or without ribavirin for the treatment of chronic hepatitis C virus (HCV) genotypes 1 and 4 infections in adult patients.

29 Jan 2016

Scientists find how APOBEC protein becomes dangerous when DNA replication process goes wrong

Cancer is caused by the growth of an abnormal cell which harbours DNA mutations, "copy errors" occurring during the DNA replication process. If these errors do take place quite regularly without having any damaging effect on the organism, some of them affect a specific part of the genome and cause the proliferation of the mutant cell, which then invades the organism.

25 Jan 2016

Penn study provides new insight into cause of peripartum cardiomyopathy in pregnant women

Each year approximately 1 in 1,000 pregnant women will experience peripartum cardiomyopathy, an uncommon form of often severe heart failure that occurs in the final month of pregnancy or up to five months following delivery. But the cause of peripartum cardiomyopathy has been largely unknown - until now.

7 Jan 2016

Scientists find genetic link to unexplained heart failure affecting pregnant women

Scientists have found that women who suffer unexplained heart failure towards the end of pregnancy or shortly after giving birth share certain genetic changes.

7 Jan 2016

Leading researchers reject proposed link between adeno-associated virus 2 and hepatocellular carcinoma

The conclusion drawn from a recent study that insertion of adeno-associated virus 2 (AAV2) into human DNA causes mutations leading to the development of hepatocellular carcinoma (HCC) was resoundingly rejected by leading researchers in the fields of gene therapy and molecular genetics.

7 Jan 2016

Janssen collaborates with Bavarian Nordic to develop, commercialize vaccine for chronic HPV infections

Janssen Pharmaceuticals, Inc. announced today that the company has entered into a definitive collaboration and license agreement with Bavarian Nordic to leverage their MVA-BN technology, jointly with Janssen's own AdVac® technology, in the development and commercialization of a heterologous prime-boost vaccine for the treatment of Human Papillomavirus (HPV) chronic infections which can lead to cancer.

20 Dec 2015

New discovery could open door to potential treatment for West Nile virus and Dengue virus infections

A new discovery from the University of Alberta's Faculty of Medicine & Dentistry could open the door to one day treat or prevent diseases caused by West Nile virus and Dengue virus infections.

18 Dec 2015

Prophylaxis treatment can protect children who receive liver transplants from HBV-infected donors

Researchers have found that a prophylaxis treatment can prevent new-onset hepatitis B in children who receive liver transplants from donors who were previously infected with hepatitis B virus (HBV) but had successfully cleared the virus.

16 Dec 2015

Study points to new avenue for developing potential strategies to thwart HIV virus

Nearly 37 million people worldwide are living with HIV. When the virus destroys so many immune cells that the body can't fight off infection, AIDS will develop. The disease took the lives of more than a million people last year.

26 Nov 2015

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a study in The Journal of Infectious Diseases.

25 Nov 2015

Viral Disease News and Research

UT Southwestern scientists discover mutation that causes X-linked reticulate pigmentary disorder

Antibodies given within one day of SHIV exposure can clear the virus

Heart failure drug has unexpected ability to block herpesvirus infection

Researchers find new innate immunity pathway that protects mammals from viral oncogenesis

Mayo Clinic develops 'The ABCs of Influenza' flash cards

Bonn scientists identify immune factor partially responsible for chronic viral infection

Rehabilitation-induced reorganization of damaged brain circuits responsible for functional recovery

Variations in Tie2 gene play significant role in patient responses to infections

Unlocking intrinsically disordered proteins: an interview with Peter Wright

Certain viral infections during pregnancy could cause behavioral changes in offspring

Zepatier receives FDA approval for treatment of chronic HCV genotypes 1 and 4 infections

Scientists find how APOBEC protein becomes dangerous when DNA replication process goes wrong

Penn study provides new insight into cause of peripartum cardiomyopathy in pregnant women

Scientists find genetic link to unexplained heart failure affecting pregnant women

Leading researchers reject proposed link between adeno-associated virus 2 and hepatocellular carcinoma

Janssen collaborates with Bavarian Nordic to develop, commercialize vaccine for chronic HPV infections

New discovery could open door to potential treatment for West Nile virus and Dengue virus infections

Prophylaxis treatment can protect children who receive liver transplants from HBV-infected donors

Study points to new avenue for developing potential strategies to thwart HIV virus

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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