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Study could pave the way for synergistic therapeutic combinations to better treat SF3B1-mutant MDS

A new study from researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations provides insight into the underlying mechanisms of gene mutations commonly seen in patients with myelodysplastic syndromes (MDS) and other myeloid neoplasms.

11 Dec 2023

Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

Study demonstrates that inhibiting stromal class I histone deacetylases (HDACs) can effectively slow down pancreatic cancer progression, shedding light on a new therapeutic approach targeting the tumor microenvironment.

10 Dec 2023

VUB researchers develop a nanobody-based technology to prevent liver inflammation

Mathieu Vinken, a professor in the In Vitro Toxicology and Dermato-cosmetology (IVTD) lab at the Vrije Universiteit Brussel, and doctoral student Raf Van Campenhout have developed a technique based on nanobody technology to prevent liver inflammation.

8 Dec 2023

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into mRNAs affects ribosomal frameshifting and the overall fidelity of mRNA translation.

7 Dec 2023

Promising candidate medication for preventing and reversing fentanyl-induced overdose

Researchers assessed CSX-1004, a monoclonal antibody (mAb), for its efficacy in reversing fentanyl overdose based on its high affinity for fentanyl, positive animal model results, and safe pharmacokinetic profile, positioning it as a potential solution in the opioid crisis.

7 Dec 2023

New study classifies CSU skin eruptions into five categories using mathematical modeling

Chronic spontaneous urticaria (CSU), a skin condition marked by sudden eruptions.

6 Dec 2023

Research shows how HIV drug could stop many coronavirus diseases

Coronaviruses are a global public health risk, with three highly infectious species, including SARS-CoV-2, emerging in the last 20 years.

5 Dec 2023

Organoid model unveils secrets of the brain's dopaminergic system

A new organoid model of the dopaminergic system sheds lights on its intricate functionality and potential implications for Parkinson's disease.

5 Dec 2023

FDA clears Beckman Coulter Life Sciences AQUIOS STEM System for stem cell analysis

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, has received 510(k) clearance from the Food and Drug Administration (FDA) to distribute its popular AQUIOS STEM System in the United States.

From Beckman Coulter Life Sciences 4 Dec 2023

New insights into the interplay between prions and TDP-43 in neurodegenerative pathology

Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death.

4 Dec 2023

LysoPI lipids show promise in boosting insulin secretion in diabetics

While sugar is the most frequently named culprit in the development of type 2 diabetes, a better understanding of the role of fats is also essential.

4 Dec 2023

CN Bio PhysioMimix Organ-on-a-Chip data supports Inipharm’s INI-822 for metabolic liver disease treatment now in clinical testing

CN Bio today announced its PhysioMimix® assay for Non-alcoholic steatohepatitis (NASH).

From CN-Bio 4 Dec 2023

Temporal morphogen-driven neural induction spurs growth of expanded brain organoids with enhanced neuroepithelium formation

Researchers examinea the effects of temporal morphogen gradient during neural induction on the formation of brain organoids.

4 Dec 2023

Canadian researchers aim to reduce chronic inflammation and comorbidities in HIV patients

To mark the occasion of World AIDS Day, find out how Dr. Madeleine Durand and Andrés Finzi are working to reduce chronic inflammation and the risk of comorbidities in people living with HIV.

30 Nov 2023

The effects of vitamin K on bone health

Existing scientific data on the effects of vitamin K (VK) on bone health and elucidated the underlying mechanisms.

30 Nov 2023

Drug-eluting hydrogel has enhanced capabilities for treating hepatocellular carcinoma

Scientists from the Terasaki Institute for Biomedical Innovation (TIBI) have developed an injectable or catheter-administered hydrogel with enhanced capabilities for treating hepatocellular carcinoma (HCC), a deadly form of liver cancer.

29 Nov 2023

BioEcho Life Sciences enters the US diagnostic market with an FDA-listed product

The EchoLUTION Viral RNA/DNA Kit is now available for the US diagnosis market to extract nucleic acids from viral particles with a single-step centrifugation technology, reducing processing time for in vitro diagnostic analysis.

From BioEcho Life Sciences GmbH 28 Nov 2023

Study finds diet-derived trans-vaccenic acid boosts anti-tumor immunity

Dietary components that impact anti-tumor immunity.

28 Nov 2023

Biodegradable patch holds promise of correcting congenital heart defects in infants

Using laboratory engineered tissue, scientists at the University of Colorado Anschutz Medical Campus have created a full thickness, biodegradable patch that holds the promise of correcting congenital heart defects in infants, limiting invasive surgeries and outlasting current patches.

27 Nov 2023

Genetic mutation in OXR1 gene linked to brain development issues

Study investigates the effects of a loss-of-function mutation in the OXR1 gene on neurodevelopment and cellular functions in the human brain. The research shows that OXR1 deficiency impairs neural differentiation, increases sensitivity to oxidative stress, and alters histone methylation, impacting brain development and potentially contributing to neurological disorders.

27 Nov 2023

in vitro News and Research

Study could pave the way for synergistic therapeutic combinations to better treat SF3B1-mutant MDS

Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

VUB researchers develop a nanobody-based technology to prevent liver inflammation

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Promising candidate medication for preventing and reversing fentanyl-induced overdose

New study classifies CSU skin eruptions into five categories using mathematical modeling

Research shows how HIV drug could stop many coronavirus diseases

Organoid model unveils secrets of the brain's dopaminergic system

FDA clears Beckman Coulter Life Sciences AQUIOS STEM System for stem cell analysis

New insights into the interplay between prions and TDP-43 in neurodegenerative pathology

LysoPI lipids show promise in boosting insulin secretion in diabetics

CN Bio PhysioMimix Organ-on-a-Chip data supports Inipharm’s INI-822 for metabolic liver disease treatment now in clinical testing

Temporal morphogen-driven neural induction spurs growth of expanded brain organoids with enhanced neuroepithelium formation

Canadian researchers aim to reduce chronic inflammation and comorbidities in HIV patients

The effects of vitamin K on bone health

Drug-eluting hydrogel has enhanced capabilities for treating hepatocellular carcinoma

BioEcho Life Sciences enters the US diagnostic market with an FDA-listed product

Study finds diet-derived trans-vaccenic acid boosts anti-tumor immunity

Biodegradable patch holds promise of correcting congenital heart defects in infants

Genetic mutation in OXR1 gene linked to brain development issues

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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