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Phase 3 study of tanezumab in patients with osteoarthritis pain meets all three co-primary endpoints

Pfizer Inc. and Eli Lilly and Company today announced that a 16-week Phase 3 study in patients with osteoarthritis pain evaluating subcutaneous administration of tanezumab, an investigational humanized monoclonal antibody, met all three co-primary endpoints.

19 Jul 2018

A simple pill for meth addicts on the cards

Researchers from Australia's Curtin University have developed a simple pill that could be used to treat methamphetamine addicts. It would soon be tried in a clinical trial to prove its efficacy and utility said the researchers.

18 Jul 2018

Health burdens of very high risk drinking are potentially large, study reveals

In an Addiction Biology study, the estimated prevalence of very high risk drinking level (VHRDL, defined as drinking >100 g of ethanol per day) in 13 European Union countries was 0.74-0.85 percent, with a risk of disease or injury of 13.5 per 100 people with VHRDL per year.

18 Jul 2018

Early childhood adversity increases sensitivity of the body's immune response to cocaine

Childhood adversity permanently alters the peripheral and central immune systems, increasing the sensitivity of the body's immune response to cocaine, reports a study by researchers at the IRCCS Santa Lucia Foundation and University of Rome "La Sapienza", Italy.

17 Jul 2018

Hunger hormones could be key to new treatments for drug, alcohol addiction

Hormones that signal the body's state of hunger and fullness could be the key to new treatments for drug and alcohol addiction.

17 Jul 2018

Scientists identify potential target for the treatment of binge eating

A small group of nerve cells located in the hypothalamus could provide a promising therapeutic target for the control of binge eating among obese individuals.

17 Jul 2018

Study: White adolescent boys experiencing early puberty have high risk for substance use

White adolescent boys experiencing early puberty are at higher risk for substance use than later developing boys, a new Purdue University study finds.

17 Jul 2018

Routine screening, treatment could help stem nationwide opioid epidemic

To help stem the nationwide opioid epidemic and related increases in HIV, hepatitis C and other infections, health care providers should routinely screen and treat patients for opioid abuse when they come to clinics and hospitals seeking other services.

16 Jul 2018

High opioid doses, concurrent sedative use are key factors for overdose risk in Medicaid recipients

Among Medicaid recipients taking prescription opioids, high opioid doses and concurrent treatment with benzodiazepine sedatives are among the key, potentially modifiable risk factors for fatal overdose, reports a study in the August issue of Medical Care.

13 Jul 2018

Researchers uncover gene that plays role in cocaine addiction

Cocaine can have a devastating effect on people. It directly stimulates the brain's reward center, and, more importantly, induces long-term changes to the reward circuitry that are responsible for addictive behaviors.

12 Jul 2018

Study finds disrupted stress response in people with schizophrenia

Stressful situations affect the brain and body differently in people with schizophrenia compared to people without the mental illness or individuals at high risk for developing psychosis, a new CAMH study shows.

11 Jul 2018

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Researchers from Case Western Reserve University School of Medicine have found a nanobody that holds promise to advance targeted therapies for a number of neurological diseases and cancer.

10 Jul 2018

Research shows greater numbers of new smokers, e-cigarette users among young adults

Millennials living more dangerously and settling down later could be creating a new generation of addicted smokers and e-cigarette users, according to the surprising results of research by The University of Texas Health Science Center at Houston.

9 Jul 2018

What a U.S.-China trade war could mean for the opioid epidemic

The American struggle to curb opioid addiction could become collateral damage in President Donald Trump's showdown on trade.

6 Jul 2018

Non-opioid drug shows promise for treating pain by targeting receptors on immune cells

Faced with the epidemic of opioid addiction, researchers have been charged with finding other strategies to treat pain. Their efforts largely have focused on nerve cells that transmit pain signals to the spinal cord and brain.

6 Jul 2018

Texas clinics busting traditional silos of mental and physical health care

Kerstin Taylor fought alcohol and substance abuse problems for two decades. She periodically sought help through addiction and psychiatric treatments to stay sober, but she continued to relapse.

5 Jul 2018

Nurses take on expanded roles to provide access to health care in rural, underserved areas

To help address access to health care for rural and underserved areas, registered nurses can take on expanded roles in primary care delivery.

4 Jul 2018

Tennessee-based pain management group to close clinics amid financial turmoil

One of the largest pain management groups in the Southeast is closing multiple clinics amid worsening financial troubles and a federal criminal investigation that targeted its former chief executive.

4 Jul 2018

Streamlining and translating basic science discoveries into the clinic

To make sure that good ideas to enhance healthcare are not lost due to a lack of resources, a growing number of centers at Penn Medicine organize forums to pitch ideas to improve medical devices and technology, hold annual competitions to fund studies to improve patient care while keeping costs down, and sponsor seed grants for programs focused on patients who need individualized tailoring of their treatment.

2 Jul 2018

Psychedelics and their role in treatment of mental health disorders

Psychedelics such as LSD, magic mushrooms, mescaline etc. have garnered renewed interest in the scientific world because of the possible role they could play in mental health problems. Ketamine remains the only hallucinogen at present that is used clinically as an anesthetic agent. The others are all classified under banned drugs.

2 Jul 2018

Addiction News and Research

Phase 3 study of tanezumab in patients with osteoarthritis pain meets all three co-primary endpoints

A simple pill for meth addicts on the cards

Health burdens of very high risk drinking are potentially large, study reveals

Early childhood adversity increases sensitivity of the body's immune response to cocaine

Hunger hormones could be key to new treatments for drug, alcohol addiction

Scientists identify potential target for the treatment of binge eating

Study: White adolescent boys experiencing early puberty have high risk for substance use

Routine screening, treatment could help stem nationwide opioid epidemic

High opioid doses, concurrent sedative use are key factors for overdose risk in Medicaid recipients

Researchers uncover gene that plays role in cocaine addiction

Study finds disrupted stress response in people with schizophrenia

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Research shows greater numbers of new smokers, e-cigarette users among young adults

What a U.S.-China trade war could mean for the opioid epidemic

Non-opioid drug shows promise for treating pain by targeting receptors on immune cells

Texas clinics busting traditional silos of mental and physical health care

Nurses take on expanded roles to provide access to health care in rural, underserved areas

Tennessee-based pain management group to close clinics amid financial turmoil

Streamlining and translating basic science discoveries into the clinic

Psychedelics and their role in treatment of mental health disorders

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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