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Efficient non-neutralizing antibody to SARS-CoV-2 spike NTD that operates via Fc receptor-mediated pathway

This study revealed that the CV3-13 antibody can mediate Fc effector functions against S protein-expressing cells.

13 Sep 2021

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

In a recent study, authors explore the relationship between age and immune response to COVID-19.

13 Sep 2021

Scientists develop a novel and potent SARS-CoV-2 RBD-homodimer vaccine

A recent report published in the journal Cell Discovery has described the immunogenicity and protective efficacy of a novel coronavirus disease 2019 (COVID-19) subunit vaccine candidate. The vaccine induces robust immune responses in rodents and non-human primates and protects the animals against severe disease.

12 Sep 2021

No evidence of pre-existing antibody and B cell immunity against SARS-CoV-2 in unexposed adults

A group of researchers analyzed the B cell response to SARS-CoV-2 in unexposed individuals.

10 Sep 2021

Mu SARS-CoV-2 variant highly resistant to neutralization by convalescent and vaccinated sera

Researchers in Japan have warned that the Mu (B.1.621) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – appears to be highly resistant to neutralization by sera from convalescent or vaccinated individuals.

8 Sep 2021

New vaccinia-based COVID-19 vaccine candidate induces robust, durable immune responses

Researchers in Australia have developed a coronavirus disease 2019 (COVID-9) vaccine that induced robust and long-lived humoral and cellular immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in both young and aging mice.

8 Sep 2021

Highly neutralizing human convalescent plasma reduces lung inflammation in SARS-CoV-2-infected macaques

A new study reignites the debate regarding the therapeutic utility of convalescent plasma in treating others with the COVID-19.

7 Sep 2021

Novel assay helps identify factors that can convert normal cells into liver cancer cells

Researchers at the University of Helsinki could show for the first time that normal human fibroblast cells can be converted to specific cancer cells using only factors that are commonly detected in actual human patients.

7 Sep 2021

Multiplexed electrochemical sensor platform enables simultaneous detection of SARS-CoV-2 RNA and host antibodies

Scientists from the UK and USA have developed an antifouling nanocomposite-coated multiplexed electrochemical sensor platform that can simultaneously detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA and virus-specific antibodies. The platform has shown 100% accuracy in detecting viral RNA and IgG-specific anti-SARS-CoV-2 antibodies. The study is currently available on the medRxiv* preprint server.

6 Sep 2021

Implications of persistent SARS-CoV-2 infection in patients with lymphoid malignancies

In a recent study, scientists attempt to understand persistent COVID-19 and its implications in patients with hematologic malignancies.

6 Sep 2021

Study reveals Pfizer/BioNTech and Oxford/AstraZeneca COVID-19 vaccine efficacy and immune response in clinically vulnerable individuals

The current study found that a strong S-antibody response occurs following complete vaccination with two different COVID-19 vaccines.

6 Sep 2021

Simple, non-invasive tool obviates unnecessary surgery in patients with colorectal cancer

A blood RNA test predicts whether residual tumour cells remain in early-stage colon cancer patients and obviates unnecessary surgery.

6 Sep 2021

Cancer treatment with terpyridine platinum compounds induces telomere dysfunction, chromosome instability

Oncotarget published "Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells" which reported that this assay is based on the use of two isogenic HT1080 cell lines, one carrying a linear HAC and the other carrying a circular HAC.

6 Sep 2021

Decreased COVID-19 vaccine efficacy amongst IBS patients receiving anti-TNFα drugs

In a paper recently uploaded to the preprint server medRxiv* by Edelman-Klapper et al., the efficacy of the mRNA vaccine is examined amongst IBD patients and compared with healthy volunteers, finding reduced efficacy amongst those receiving anti-TNFα medication.

6 Sep 2021

Characterization of SARS-CoV-2 viral trajectory

In a study available on the preprint server medRxiv* researchers aimed to characterize early viral shedding in patients with incident infection. Read more here.

6 Sep 2021

Efficacy of vaccines against the SARS-CoV-2 Delta variant

A new study uses statistical models to determine vaccine efficacy against the various SARS-CoV-2 variants and clinical endpoints for SARS-CoV-2 variants.

5 Sep 2021

Home blood collection device could be used for measuring antibodies against SARS-CoV-2

A device that could make it possible for patients to draw their own blood at home was successfully used to collect blood samples for measuring antibodies against SARS-CoV-2, the virus that causes COVID-19, researchers at the University of Washington School of Medicine in Seattle report.

4 Sep 2021

Lysis Buffer for High Yield Enzymatic Shearing

Porvair Sciences reports how its Chromatrap® Lysis buffer for enzymatic shearing provides users with a complete lysis buffer for the disruption of nuclear cell membranes with a milder detergent than that required for mechanical fragmentation.

From Chromatrap® - Porvair Sciences Ltd 3 Sep 2021

UVA research quantifies the antibody response generated by Pfizer and Moderna COVID vaccines

New research from the University of Virginia School of Medicine quantifies the antibody response generated by the Pfizer and Moderna COVID vaccines.

3 Sep 2021

Simple and rapid method measures T-cell immune response to SARS-CoV-2 virus

Researchers from Duke-NUS Medical School, together with collaborators from the National Centre for Infectious Diseases (NCID) and Singapore General Hospital (SGH), have discovered a simple and rapid method to measure the T-cell immune response to the SARS-CoV-2 virus, which causes COVID-19.

3 Sep 2021

Assay News and Research

Efficient non-neutralizing antibody to SARS-CoV-2 spike NTD that operates via Fc receptor-mediated pathway

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

Scientists develop a novel and potent SARS-CoV-2 RBD-homodimer vaccine

No evidence of pre-existing antibody and B cell immunity against SARS-CoV-2 in unexposed adults

Mu SARS-CoV-2 variant highly resistant to neutralization by convalescent and vaccinated sera

New vaccinia-based COVID-19 vaccine candidate induces robust, durable immune responses

Highly neutralizing human convalescent plasma reduces lung inflammation in SARS-CoV-2-infected macaques

Novel assay helps identify factors that can convert normal cells into liver cancer cells

Multiplexed electrochemical sensor platform enables simultaneous detection of SARS-CoV-2 RNA and host antibodies

Implications of persistent SARS-CoV-2 infection in patients with lymphoid malignancies

Study reveals Pfizer/BioNTech and Oxford/AstraZeneca COVID-19 vaccine efficacy and immune response in clinically vulnerable individuals

Simple, non-invasive tool obviates unnecessary surgery in patients with colorectal cancer

Cancer treatment with terpyridine platinum compounds induces telomere dysfunction, chromosome instability

Decreased COVID-19 vaccine efficacy amongst IBS patients receiving anti-TNFα drugs

Characterization of SARS-CoV-2 viral trajectory

Efficacy of vaccines against the SARS-CoV-2 Delta variant

Home blood collection device could be used for measuring antibodies against SARS-CoV-2

Lysis Buffer for High Yield Enzymatic Shearing

UVA research quantifies the antibody response generated by Pfizer and Moderna COVID vaccines

Simple and rapid method measures T-cell immune response to SARS-CoV-2 virus

Understanding the DNA Damage Response in Innate Immunity eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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