Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

IPF-PRO Registry data sheds light on characteristics of people with idiopathic pulmonary fibrosis

Boehringer Ingelheim Pharmaceutical, Inc. today announced initial results of the first 49 people enrolled in the IPF-PRO Registry, which shed light on characteristics of people with IPF at the time of diagnosis.

23 Oct 2015

Ember Therapeutics reports initial results from BMP-7 Phase II trial in patients with moderate osteoarthritis of the knee

Ember Therapeutics, Inc., a privately held, New York-based biopharmaceutical company that is developing targeted therapies for osteoarthritis, kidney fibrosis, and other indications using Bone Morphogenetic Protein (BMP)-7, announced today initial results from the Phase II(a) trial of local BMP-7 administration in patients with moderate osteoarthritis of the knee.

20 Oct 2015

Quest Diagnostics scientists demonstrate new molecular combing technique that predicts cystic fibrosis, muscular dystrophy

Genetic testing for mutations beyond those currently recommended in medical guidelines may aid the identification of more couples at risk of having a child with cystic fibrosis, according to a study presented today at the 2015 American Society of Human Genetics Annual Meeting, which runs through October 10 in Baltimore, Maryland.

From Quest Diagnostics 13 Oct 2015

Roche to acquire biotechnology company, Adheron Therapeutics

Adheron Therapeutics, a privately held biotechnology company based in Berkeley, California, United States, announced today that it has agreed to be acquired by Roche.

9 Oct 2015

Mysterious kidney disease may be caused by chronic dehydration tied to global climate change

A mysterious kidney disease that has killed over 20,000 people in Central America, most of them sugar cane workers, may be caused by chronic, severe dehydration linked to global climate change, according to a new study by Richard J. Johnson, MD, of the University of Colorado Anschutz Medical Campus.

9 Oct 2015

Celtaxsys commences acebilustat phase 2 trial in patients with cystic fibrosis in US

Celtaxsys, a clinical stage drug development company focused on advancing care for patients suffering from orphan inflammatory diseases, announced today the commencement of the US arm of an international phase 2 clinical trial for its flagship compound, acebilustat, in patients with cystic fibrosis (CF).

8 Oct 2015

Genetic carrier screening: an interview with Don Hardison, CEO of Good Start Genetics

Carrier screening provides you and your doctor with information about your risks of having a child with a serious genetic disease prior to or during pregnancy.

6 Oct 2015

Tarix Orphan's TXA127 granted FDA Fast Track Designation for treatment of DMD patients

Tarix Orphan LLC, a privately held biopharmaceutical company focused on the treatment of rare neuromuscular disorders and connective tissue diseases, today announced that the U.S. Food and Drug Administration has granted Fast Track Designation to TXA127 (angiotensin 1-7) to reduce skeletal muscle damage and fibrosis and thereby improve muscle strength in Duchenne Muscular Dystrophy (DMD) patients.

6 Oct 2015

Understanding HCV disease progression rates among PWID

The Hepatitis C virus (HCV) infection is a chronic blood-borne viral infection that affects an estimated 160 million people, or 2-3% of the population world-wide. Alarmingly, chronic HCV infection accounts for one-quarter of the cases of cirrhosis and hepatocellular carcinoma (HCC). If HCV is left untreated, chronic liver disease will occur in 60-70% of the cases, cirrhosis in 5-20% of the cases, and 1-5% will die from decompensated cirrhosis or HCC.

6 Oct 2015

Presence of blood eosinophilia during NEC predicts life-threatening complications for preemies

Premature infants have heightened risks of deadly diseases because their organs and immune systems are not fully developed. Necrotizing enterocolitis (NEC), a major gastrointestinal disease that causes the intestines to die, is a leading cause of death among these infants and is the most the common disease for babies born before 32 weeks.

1 Oct 2015

Stony Brook Children's Hospital follows pain management protocols to treat pain in pediatric patients

Stony Brook Children's Hospital clinicians follow pain management protocols to proactively, preemptively, and consistently treat pain in each and every pediatric patient. Known as the Ouchless Approach to Pediatric Medicine, Margaret McGovern, MD, PhD, Physician-in-Chief, describes it as the cornerstone of treatment for pediatric patients at Stony Brook Children's.

30 Sep 2015

New report implicates five genetic regions that play major roles in CF disease severity

If you have two faulty copies of the CFTR gene, you will have cystic fibrosis. But the severity of your disease will depend on environmental factors and many other genes. Locating these genes and altering their function could lead to new therapies.

29 Sep 2015

Breakthrough research to be presented at AAO-HNSF 2015 Annual Meeting & OTO EXPO

Research to be presented tomorrow at the 2015 Annual Meeting & OTO EXPOSM of the American Academy of Otolaryngology--Head and Neck Surgery Foundation (AAO-HNSF) spans across the otolaryngology specialty.

29 Sep 2015

Health effects of occupational exposure to talc

Talc, a substance commonly used in a number of manufacturing processes, including many in the food processing industry, is a health hazard and exposure to it should be closely monitored, say researchers from The Netherlands.

28 Sep 2015

Research reveals significant information about the dynamics of bacterial gels

Research by scientists at the University of York has revealed important new information about the dynamics of bacterial gels which could ultimately suggest new ways of helping prevent or better control diseases such as cystic fibrosis.

26 Sep 2015

Boehringer Ingelheim, BioMed X apply crowdsourcing approach to establish research team for identifying COPD treatment

Boehringer Ingelheim and BioMed X announced today that they have successfully applied a crowdsourcing approach to establish a research team of outstanding scientists from around the world with bright ideas, who will endeavor to identify new approaches for the treatment of patients with chronic obstructive pulmonary disease (COPD).

21 Sep 2015

Novel nebuliser could one day deliver life-saving cancer drugs

A revolutionary nebuliser developed by RMIT University researchers could one day deliver life-saving cancer drugs and vaccines traditionally given by injection.

21 Sep 2015

Hermansky-Pudlak syndrome can cause debilitating lung disease in Puerto Ricans

A hereditary condition called Hermansky-Pudlak syndrome (HPS) can cause bleeding problems, low vision, albinism and, in some patients, a debilitating lung disease.

21 Sep 2015

Ex-vivo lung perfusion technique can reduce risk of transplant rejection

University of Manchester researchers have used a new technique to recondition poorly functioning lungs and remove donor white blood cells in an attempt to increase the number of lungs available for transplant, and at the same time reduce the risk of acute rejection.

15 Sep 2015

Study may help scientists to better understand complications caused by drug therapy in kidney transplant patients

New research will help scientists and medical professionals to better understand the long-term complications caused by an immunosuppressant drug used to treat thousands of kidney transplant patients.

11 Sep 2015

Fibrosis News and Research

Further Reading

IPF-PRO Registry data sheds light on characteristics of people with idiopathic pulmonary fibrosis

Ember Therapeutics reports initial results from BMP-7 Phase II trial in patients with moderate osteoarthritis of the knee

Quest Diagnostics scientists demonstrate new molecular combing technique that predicts cystic fibrosis, muscular dystrophy

Roche to acquire biotechnology company, Adheron Therapeutics

Mysterious kidney disease may be caused by chronic dehydration tied to global climate change

Celtaxsys commences acebilustat phase 2 trial in patients with cystic fibrosis in US

Genetic carrier screening: an interview with Don Hardison, CEO of Good Start Genetics

Tarix Orphan's TXA127 granted FDA Fast Track Designation for treatment of DMD patients

Understanding HCV disease progression rates among PWID

Presence of blood eosinophilia during NEC predicts life-threatening complications for preemies

Stony Brook Children's Hospital follows pain management protocols to treat pain in pediatric patients

New report implicates five genetic regions that play major roles in CF disease severity

Breakthrough research to be presented at AAO-HNSF 2015 Annual Meeting & OTO EXPO

Health effects of occupational exposure to talc

Research reveals significant information about the dynamics of bacterial gels

Boehringer Ingelheim, BioMed X apply crowdsourcing approach to establish research team for identifying COPD treatment

Novel nebuliser could one day deliver life-saving cancer drugs

Hermansky-Pudlak syndrome can cause debilitating lung disease in Puerto Ricans

Ex-vivo lung perfusion technique can reduce risk of transplant rejection

Study may help scientists to better understand complications caused by drug therapy in kidney transplant patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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