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Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

When a coronary artery is obstructed by atheroma, blood flow is depressed or even arrested. This causes hypoxia of cardiac cells associated with the deprivation of nutrients. In clinic, the first objective is to restore blood flow. However, this is associated with a burst in oxidation of cellular proteins and lipids. This oxidation enhances cell death and participates to the so-called reperfusion injury.

From Logos Biosystems 18 Dec 2017

Prostate cancer researchers find significant disparities between two liquid biopsy providers

Two Johns Hopkins prostate cancer researchers found significant disparities when they submitted identical patient samples to two different commercial liquid biopsy providers.

15 Dec 2017

Researchers use RNA nanotechnology to program exosomes for delivering effective cancer therapies

A new study shows that attaching antibody-like RNA nanoparticles to microvesicles can deliver effective RNA therapeutics such as small interfering RNA specifically to cancer cells.

13 Dec 2017

Researchers adopt new approach to treating advanced prostate cancer

Scientists have proposed a new approach to preventing the proliferation of prostate tumor cells that are no longer responding to treatment. Prostate cancer can usually be cured via surgical removal of the tumor and/or the use of radiotherapy, but in one-fifth of cases, patients also require treatment with drugs to continue removing tumor cells. However, these drugs are only effective for up to three years, after which the cancer continues to develop.

13 Dec 2017

Researchers discover new way to attack drug-resistant prostate cancer cells

In most cases, prostate cancer is cured by surgical removal of the tumor and/or by radiotherapy. However, 20% of patients will need treatment to remove tumor cells but this treatment ceases to be effective after two or three years and the cancer develops further.

13 Dec 2017

Novel ‘black box’ recorder captures surgeons' robotic surgery skills

You may know that your surgeon is using the latest minimally invasive technology for your surgery, but how do you know if they've mastered it? To help answer that question, researchers at Keck Medicine of USC looked to a custom recording tool similar in concept to a flight recorder on an airplane.

13 Dec 2017

Hidden genes hold blueprints for designing new anti-cancer drugs

New research suggests these hidden genes hold the blueprints for designing new, even more effective cancer-targeting compounds.

12 Dec 2017

Researchers find new role for SHARPIN protein in melanoma growth

Researchers at Sanford Burnham Prebys Medical Discovery and the Technion in Israel have found a new role for the SHARPIN protein. In addition to being one of three proteins in the linear ubiquitin chain assembly complex, regulating NFκB and other inflammatory molecules, SHARPIN modulates PRMT5, an epigenetic master switch that controls several proteins linked to melanoma. The research was published in The Journal of Clinical Investigation.

12 Dec 2017

Retirement’s revolving door: Why some workers can’t call it quits

In his view, Tim Franson utterly failed at retirement. After 20 years as a high-ranking vice president at drugmaker Eli Lilly, Franson and his wife, Chris, a successful real estate agent, thought they were quietly retiring nearly a decade ago to Bonita Springs, Fla.

11 Dec 2017

UVA researchers developing tool to help prostate cancer patients weigh treatment options

Researchers at the University of Virginia Cancer Center are developing a tool to help patients with prostate cancer better understand the potential risks and rewards of their treatment options.

8 Dec 2017

Simple blood test shows promise to predict risk of breast cancer relapse

A simple blood test that detects tumor cells circulating in the blood shows promise as a new way to predict high or low risk of a breast cancer relapse.

8 Dec 2017

New 3D-printed artificial models mimic the look and feel of real organs

A team of researchers led by the University of Minnesota has 3D printed lifelike artificial organ models that mimic the exact anatomical structure, mechanical properties, and look and feel of real organs. These patient-specific organ models, which include integrated soft sensors, can be used for practice surgeries to improve surgical outcomes in thousands of patients worldwide.

6 Dec 2017

Shorter course of radiation may be preferred treatment for men with intermediate-risk prostate cancer

Prostate cancer is the most common cancer among males in the United States. Approximately, 180,000 men are diagnosed each year, and approximately 95 percent of these men have localized disease that is potentially curable.

5 Dec 2017

PET scans can predict prostate cancer patients’ response to salvage radiation treatment

For prostate cancer patients who have rising levels of PSA (a cancer indicator) even after radical prostatectomy, early treatment makes a difference.

5 Dec 2017

Scientists investigate new role of old protein in breast cancer

Scientists led by Dr Chris Toseland of the University's School of Biosciences studied a protein called Myosin VI, a molecular motor which acts as a courier to transport other proteins within our cells.

4 Dec 2017

New CSHL method pinpoints which prostate tumors pose fatal threat before surgery

The facts about prostate cancer can be confusing. It's the third most common cancer type among Americans - 161,000 men will be diagnosed this year, the National Cancer Institute estimates. Yet according to the NCI, 98.6% will be alive in 5 years.

1 Dec 2017

Researchers identify oral bacteria linked to esophageal cancer

Researchers at NYU Langone Health's Perlmutter Cancer Center report that at least three kinds of bacteria in the mouths of Americans may heighten or lower their risk of developing esophageal cancer.

1 Dec 2017

Chemotherapy-generated debris from dead and dying cancer cells can stimulate tumor growth

Cancer therapies including radiation and chemotherapy seek to treat the disease by killing tumor cells. Now a team including researchers at Beth Israel Deaconess Medical Center have shown that the dead and dying cancer cells generated by chemotherapy and targeted cancer therapy paradoxically trigger inflammation that promotes aggressive tumor growth.

1 Dec 2017

Oral bacteria that lead to periodontal disease linked to higher risk of esophageal cancer

An analysis of bacteria present in the mouth showed that some types of bacteria that lead to periodontal disease were associated with higher risk of esophageal cancer.

1 Dec 2017

Hackensack Meridian Health Bayshore Medical Center now offers MRI/ultrasound fusion biopsy

Hackensack Meridian Health Bayshore Medical Center is proud to announce that it has expanded services to include targeted MRI ultrasound for prostate biopsy.

30 Nov 2017

Prostate News and Research

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

Prostate cancer researchers find significant disparities between two liquid biopsy providers

Researchers use RNA nanotechnology to program exosomes for delivering effective cancer therapies

Researchers adopt new approach to treating advanced prostate cancer

Researchers discover new way to attack drug-resistant prostate cancer cells

Novel ‘black box’ recorder captures surgeons' robotic surgery skills

Hidden genes hold blueprints for designing new anti-cancer drugs

Researchers find new role for SHARPIN protein in melanoma growth

Retirement’s revolving door: Why some workers can’t call it quits

UVA researchers developing tool to help prostate cancer patients weigh treatment options

Simple blood test shows promise to predict risk of breast cancer relapse

New 3D-printed artificial models mimic the look and feel of real organs

Shorter course of radiation may be preferred treatment for men with intermediate-risk prostate cancer

PET scans can predict prostate cancer patients’ response to salvage radiation treatment

Scientists investigate new role of old protein in breast cancer

New CSHL method pinpoints which prostate tumors pose fatal threat before surgery

Researchers identify oral bacteria linked to esophageal cancer

Chemotherapy-generated debris from dead and dying cancer cells can stimulate tumor growth

Oral bacteria that lead to periodontal disease linked to higher risk of esophageal cancer

Hackensack Meridian Health Bayshore Medical Center now offers MRI/ultrasound fusion biopsy

What to know about prostate cancer eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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