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World TB Day: Aeras releases new animated video to help raise awareness about TB

Aeras, a non-profit biotechnology organization developing new tuberculosis (TB) vaccines for the world, is launching a new 90-second animated video in honor of World TB Day to help raise awareness about TB’s devastating toll and the need for new tools, including vaccines, to fight this epidemic.

22 Mar 2016

University of Copenhagen researchers discover Achilles heel of bacteria

Drug resistant bacteria are fast becoming one of the big worries of the 21 century. Now researchers at the University of Copenhagen have discovered a previously unknown weakness; an "Achilles heel", of bacteria. Their discovery, a crucial step in bacteria's energy metabolism, may be the first step in developing an entirely novel form of antibiotics

22 Mar 2016

Stress management can cut risk of another heart attack by half

Patients recovering from heart attacks or other heart trouble could cut their risk of another heart incident by half if they incorporate stress management into their treatment, according to research from Duke Health.

22 Mar 2016

Key molecule in breast, lung cancer cells can help prevent spread of cancer

Scientists have revealed that a key molecule in breast and lung cancer cells can help switch off the cancers' ability to spread around the body.

22 Mar 2016

Specialized gene editing system paves way to eventual cure for HIV patients

A specialized gene editing system designed by scientists at the Lewis Katz School of Medicine at Temple University is paving the way to an eventual cure for patients infected with HIV, the virus that causes AIDS.

22 Mar 2016

Laparoscopic surgery offers safe alternative to acid reflux drugs

A new analysis indicates that death rates and the need for additional operations following laparoscopic surgery for gastro-oesophageal reflux disease are very low.

22 Mar 2016

Cell biologists identify new way for curing cancer and vessel diseases

Cell biologists from the Lomonosov Moscow State University discovered a new way of regulating of cell motility -- this discovery will make possible development of new drugs for curing onco- and vessel diseases.

22 Mar 2016

Antipsychotic drugs may do significantly more harm to Parkinson's disease patients

At least half of Parkinson's disease patients experience psychosis at some point during the course of their illness, and physicians commonly prescribe antipsychotic drugs, such as quetiapine, to treat the condition. However, a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, the University of Michigan Medical School, and the Philadelphia and Ann Arbor Veterans Affairs Medical Centers and suggests that these drugs may do significantly more harm in a subset of patients.

21 Mar 2016

Anthim (obiltoxaximab) injection approved for treatment of inhalational anthrax

On Friday, March 18, the U.S. Food and Drug Administration approved Anthim (obiltoxaximab) injection to treat inhalational anthrax in combination with appropriate antibacterial drugs. Anthim is also approved to prevent inhalational anthrax when alternative therapies are not available or not appropriate.

21 Mar 2016

KORs could be potential drug target for treatment of addiction, anxiety disorders

University of North Carolina researchers uncovered a cellular mechanism by which kappa opioid receptors (KOR) drive anxiety. These proteins inhibit the release of the neurotransmitter glutamate in a part of the brain that regulates emotion.

21 Mar 2016

Novel compound shows promise as potential treatment for acute myeloid leukemia

A novel compound has shown promise in preclinical studies as a treatment for acute myeloid leukemia, more than doubling median days of survival even in a drug-resistant form of the disease.

21 Mar 2016

Cobimetinib with vemurafenib may have added benefit in melanoma with BRAF V600 mutation

Cobimetinib (trade name: Cotellic) has been approved since November 2015 in combination with vemurafenib for the treatment of adults with advanced, i.e. metastatic or unresectable, melanoma with a BRAF V600 mutation.

21 Mar 2016

Penn study calls on physicians to avoid over-prescribing opioids for surgical patients

Physicians are prescribing more opioid painkillers than ever before to patients undergoing common surgeries, according to new research from the department of Anesthesiology and Critical Care at the Perelman School of Medicine at the University of Pennsylvania.

21 Mar 2016

New type of nerve cells appears to control feeding behaviors in mice

While researching the brain's learning and memory system, scientists at Johns Hopkins say they stumbled upon a new type of nerve cell that seems to control feeding behaviors in mice. The finding, they report, adds significant detail to the way brains tell animals when to stop eating and, if confirmed in humans, could lead to new tools for fighting obesity. Details of the study will be published by the journal Science on March 18.

20 Mar 2016

Study associates prevalence of homosexual relations in Uganda with increased health risks

The results are based on a survey with nearly 3,000 participating students in south-western Uganda. The students responded to a number of questions, including aspects concerning sexuality, physical and mental health, sexual risk behaviour, and experiences with drugs. The questions about homosexuality pertained to the students' emotions as well as their actions.

19 Mar 2016

Neutralizing acidic tumor environment increases efficacy of immune-targeting cancer therapies

Cancer cells have the ability to grow in an acidic tumor environment that is detrimental to other cells, including immune cells. In a Cancer Research cover article published this week, Moffitt Cancer Center reported that neutralizing the acidic tumor environment increases the efficacy of several immune-targeting cancer therapies.

19 Mar 2016

Paracetamol does not meet minimum standard of clinical effectiveness in osteoarthritis patients

In a large-scale analysis of pain-relief medication for osteoarthritis, researchers found that paracetamol does not meet the minimum standard of clinical effectiveness in reducing pain or improving physical function in patients with knee and hip osteoarthritis.

18 Mar 2016

Brain's immune cells play direct role in development of amyotrophic lateral sclerosis

Cedars-Sinai research scientists have found that immune cells in the brain play a direct role in the development of amyotrophic lateral sclerosis, or ALS, offering hope for new therapies to target the neurodegenerative disease that gradually leads to paralysis and death.

18 Mar 2016

Genomic profiling could help provide targeted therapies for difficult to treat cancer tumors

Research from Rutgers Cancer Institute of New Jersey examining difficult to treat cancer tumors through genomic profiling shows that tumors with alterations in a signaling pathway responsible for cell regulation may respond to targeted therapy regardless of where the tumor originated in the body.

18 Mar 2016

Clinical study finds no added benefit of using four TB drugs to save people with advanced HIV/AIDS

In a report on the so-called REMEMBER (Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment) study -- a 10-nation, randomized clinical trial of adult outpatients -- investigators concluded that there was no added benefit of using four drugs for TB over just using one drug, isoniazid, to save lives in people with advanced HIV/AIDS.

18 Mar 2016

Drugs News and Research

World TB Day: Aeras releases new animated video to help raise awareness about TB

University of Copenhagen researchers discover Achilles heel of bacteria

Stress management can cut risk of another heart attack by half

Key molecule in breast, lung cancer cells can help prevent spread of cancer

Specialized gene editing system paves way to eventual cure for HIV patients

Laparoscopic surgery offers safe alternative to acid reflux drugs

Cell biologists identify new way for curing cancer and vessel diseases

Antipsychotic drugs may do significantly more harm to Parkinson's disease patients

Anthim (obiltoxaximab) injection approved for treatment of inhalational anthrax

KORs could be potential drug target for treatment of addiction, anxiety disorders

Novel compound shows promise as potential treatment for acute myeloid leukemia

Cobimetinib with vemurafenib may have added benefit in melanoma with BRAF V600 mutation

Penn study calls on physicians to avoid over-prescribing opioids for surgical patients

New type of nerve cells appears to control feeding behaviors in mice

Study associates prevalence of homosexual relations in Uganda with increased health risks

Neutralizing acidic tumor environment increases efficacy of immune-targeting cancer therapies

Paracetamol does not meet minimum standard of clinical effectiveness in osteoarthritis patients

Brain's immune cells play direct role in development of amyotrophic lateral sclerosis

Genomic profiling could help provide targeted therapies for difficult to treat cancer tumors

Clinical study finds no added benefit of using four TB drugs to save people with advanced HIV/AIDS

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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