Drugs News and Research

RSS

Treatment guidelines need to be changed for rare, genetic form of diabetes, study suggests

Patients with a rare, genetic form of diabetes often are misdiagnosed as having type 2 diabetes because the two share symptoms.

18 Mar 2016

CIRM approves $6.3 million grant to support research on novel stem cell-based therapy for ALS

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine approved yesterday a $6.3 million grant to a research team from the University of California, San Diego School of Medicine and University of California, Davis to pursue a novel human embryonic stem cell-based therapy to rescue and restore neurons devastated by amyotrophic lateral sclerosis or ALS.

18 Mar 2016

Vascular events in CML may not be linked to TKI therapy

The increased risk of vascular events observed among elderly patients with chronic myeloid leukaemia, compared with patients without cancer, may not be driven by tyrosine kinase inhibitor therapy, US researchers suggest.

17 Mar 2016

Older types of arthritis medicine appear to be dangerous for the heart

Many Danes are prescribed NSAIDs for the treatment of painful conditions, fever and inflammation. But the treatment also comes with side effects, including the risk of ulcers and increased blood pressure.

17 Mar 2016

Researchers find major gap in treatment for AF patients at higher risk for stroke

Nearly half of all atrial fibrillation (AF) patients at the highest risk for stroke are not being prescribed blood thinners by their cardiologists, according to a new study by researchers at University of California, San Diego School of Medicine and University of California, San Francisco.

17 Mar 2016

WSU researcher explores new drugs to treat neurological disorders linked to autophagic dysfunction

Repairing the brain's "house-cleaning function," which could help people with Alzheimer's, Parkinson's, amyotrophic lateral sclerosis (ALS) and 100 other diseases, is the focus of recently funded research at Washington State University.

17 Mar 2016

Study finds disparities in discontinuing diabetes drug rosiglitazone following FDA safety alert

Among older adults with diabetes, certain subgroups--including white patients and those with lower incomes--were slower to discontinue the diabetes drug rosiglitazone after a US Food and Drug Administration safety alert, reports a study in the April issue of Medical Care.

17 Mar 2016

New study reveals why certain cancer drugs not always effective in halting tumor growth

New cancer drugs allow doctors to tailor treatment based on the genetic profile of a patient's tumor. However, these drugs don't work at all in some patients, and they lose their effectiveness in others.

17 Mar 2016

Automated techniques could dramatically accelerate antimicrobial discovery

The antimicrobial arsenal that we count on to save millions of lives each year is alarmingly thin--and these microbes are rapidly evolving resistance to our weapons. But help may be on the way: In a study posted in the AMB Express, researchers from the National Institute of Standards and Technology show that automated techniques commonly used to screen new drugs for mammalian cell toxicity could also dramatically speed up the challenging task of antimicrobial discovery.

17 Mar 2016

Psoriasis patients experience widespread bone loss

Researchers from the Genes, Development and Disease Group, headed by Erwin Wagner at the Spanish National Cancer Research Centre have discovered that psoriasis patients experience a widespread bone loss as a result of the disease.

17 Mar 2016

Biomarkers may provide novel approaches to monitoring immunosuppressive therapy in organ transplant patients

Recently discovered biomarkers may provide valuable new approaches to monitoring immunosuppressive drug therapy in organ transplant recipients--with the potential for individualized therapy to reduce organ rejection and minimize side effects, according to a special article in the April issue of Therapeutic Drug Monitoring, official journal of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology.

17 Mar 2016

Johns Hopkins scientists develop antibody to curb lung tumor cell growth, breast cancer metastasis

Johns Hopkins scientists report they have developed an antibody against a specific cellular gateway that suppresses lung tumor cell growth and breast cancer metastasis in transplanted tumor experiments in mice, according to a new study published in the February issue of Nature Communications.

17 Mar 2016

MUSC surgeon awarded $3.8 million grant to evaluate transplant drug

Seldom can one say $3.8 million is just the tip of the iceberg, but a newly awarded grant from Gilead Sciences, Inc. is just that. MUSC transplant surgeon Kenneth Chavin, M.D., Ph.D., says the true value of the multi-center drug trial is closer to $26 million, including $22 million in free drugs provided by the pharmaceutical company.

17 Mar 2016

Study: Statin drugs can reduce time to clear tuberculosis infection in mice

In a study using mice, the Johns Hopkins University School of Medicine infectious disease experts have added to evidence that statin drugs — known primarily for their cholesterol-lowering effects — can significantly reduce the time it takes to clear tuberculosis infection.

17 Mar 2016

Halozyme Therapeutics doses first patient in Halo-301 | Pancreatic study

Halozyme Therapeutics, Inc., a biotechnology company developing novel oncology and drug-delivery therapies, today announced the first patient has been dosed in its Halo-301 | Pancreatic study, a Phase 3 clinical trial in previously untreated metastatic pancreatic cancer patients.

16 Mar 2016

Research confirms potential use of iron oxide nanoparticles in biomedical applications

Iron oxides are widespread in nature and can be readily synthesized in the laboratory. Among them, hematite, magnetite and maghemite nanoparticles have particularly promising properties for biomedical applications.

16 Mar 2016

Could prebiotics benefit early life brain development? An interview with Dr Phil Burnet

Galacto-oligosaccharides are essentially sugar or saccharide molecules that have been joined together into short polymer chains.

16 Mar 2016

Many kidney transplant patients may benefit from lower-than-standard dose of CNIs

The kidney is the most commonly transplanted organ in the United States, with more than 17,000 transplants performed each year. Following kidney transplant, patients are routinely placed on a regimen of immunosuppressant medications to prevent organ rejection, which often includes calcineurin inhibitors (CNIs) as the backbone medication of this regimen.

16 Mar 2016

Mindfulness meditation reduces pain without endogenous opioid system

Everyone knows that stubbing your toe hurts. What makes it stop hurting is the body's main pain-blocking process - the natural production of opioids.

16 Mar 2016

Theoretical modelling helps to understand interior structures of cubosomes

Under certain conditions appropriately selected particles can form closed surfaces in liquids with surprisingly complex shapes, cutting through space by a regular network of channels. So far, we have looked at cubosomes - for this is what these spectacular three-dimensional nanostructures are called - only from the outside.

16 Mar 2016

Drugs News and Research

Treatment guidelines need to be changed for rare, genetic form of diabetes, study suggests

CIRM approves $6.3 million grant to support research on novel stem cell-based therapy for ALS

Vascular events in CML may not be linked to TKI therapy

Older types of arthritis medicine appear to be dangerous for the heart

Researchers find major gap in treatment for AF patients at higher risk for stroke

WSU researcher explores new drugs to treat neurological disorders linked to autophagic dysfunction

Study finds disparities in discontinuing diabetes drug rosiglitazone following FDA safety alert

New study reveals why certain cancer drugs not always effective in halting tumor growth

Automated techniques could dramatically accelerate antimicrobial discovery

Psoriasis patients experience widespread bone loss

Biomarkers may provide novel approaches to monitoring immunosuppressive therapy in organ transplant patients

Johns Hopkins scientists develop antibody to curb lung tumor cell growth, breast cancer metastasis

MUSC surgeon awarded $3.8 million grant to evaluate transplant drug

Study: Statin drugs can reduce time to clear tuberculosis infection in mice

Halozyme Therapeutics doses first patient in Halo-301 | Pancreatic study

Research confirms potential use of iron oxide nanoparticles in biomedical applications

Could prebiotics benefit early life brain development? An interview with Dr Phil Burnet

Many kidney transplant patients may benefit from lower-than-standard dose of CNIs

Mindfulness meditation reduces pain without endogenous opioid system

Theoretical modelling helps to understand interior structures of cubosomes

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News