Immune System News and Research

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New cancer vaccine protein target found

Cancer Research UK scientists have identified an important new protein target which could be used to produce highly focused vaccine therapies for cancer - according to research published in the Journal of Clinical Investigation.

25 May 2008

An alternative strategy for HIV vaccine research

Today, Advanced BioScience Laboratories, Inc. (ABL) and the University of Massachusetts Medical School (UMMS) report that their unique HIV vaccine formulation was effective in eliciting strong and balanced immune responses in healthy human volunteers.

22 May 2008

Emergency measures employed to stop measles epidemic

Emergency measures are being adopted in Britain to tackle the escalating numbers of new measles cases.

22 May 2008

Possible biological explanation for C-Section-linked allergies and asthma found

Scientists believe they may have identified a biological explanation for the link between cesarean-section delivery and risk of allergy and asthma in childhood. They will present their findings at the American Thoracic Society's 2008 International Conference in Toronto on Tuesday, May 20.

21 May 2008

DNA modification seen in colorectal tumors helps predict outcomes, John Wayne Cancer Institute researchers find

An international study led by researchers at the John Wayne Cancer Institute at Saint John's Health Center has found that modifications to DNA found on multiple chromosomes in tumors can help to predict outcomes in patients with early-stage rectal cancer.

21 May 2008

Discovery of a molecular scaffold that guides connections between brain cells

Brain cells known as neurons process information by joining into complex networks, transmitting signals to each other across junctions called synapses. But "neurons don't just connect to other neurons," emphasizes Z. Josh Huang, Ph.D., "in a lot of cases, they connect to very specific partners, at particular spots."

21 May 2008

Researchers map iron transport protein - may help people suffering from blood iron disorders

Montana State University scientists in the Department of Chemistry and Bio-chemistry published new research this week that could one day affect the lives of millions around the world who suffer from blood iron disorders.

21 May 2008

Advaxis files investigational new drug application for Lovaxin C

Advaxis Inc. completed its filing of a new investigational new drug ("IND") application with the U.S. Food and Drug Administration ("FDA"). This filing follows the successful completion of a Phase I study overseas.

20 May 2008

Trends of vitamin B6 status in US population sample identified in study

In an epidemiological study, Tufts University researchers identified trends of vitamin B6 status in a sample of the United States population based on measures of plasma pyridoxal 5'- phosphate (PLP) levels in the bloodstream. Plasma PLP is the indicator used by the federal government to set the current Recommended Dietary Allowance (RDA) of vitamin B6, a nutrient essential for red blood cell function and important for maintaining a healthy immune system and blood glucose levels.

20 May 2008

HIV/AIDS experts call for new ideas, increased funding on 25th anniversary of paper identifying virus

A novel strategy, new teams of researchers and increased funding are needed to revitalize the fight against HIV/AIDS worldwide, experts said Monday on the 25th anniversary of the release of the study that identified HIV, AFP/Google.com reports.

20 May 2008

Tuberculosis not the only risk from new immunological drugs

A new survey cautions physicians that drugs commonly prescribed for patients suffering from immunological disorders such as rheumatoid arthritis and inflammatory bowel disease may carry risks of serious infections other than the known risk of tuberculosis. The survey published is in the June 1 issue of Clinical Infectious Diseases, currently available online.

20 May 2008

Plant flavonoid luteolin reduces inflammatory response in the brain

Researchers at the University of Illinois report this week that a plant compound found in abundance in celery and green peppers can disrupt a key component of the inflammatory response in the brain. The findings have implications for research on aging and diseases such as Alzheimer's and multiple sclerosis.

20 May 2008

NIAID to advance B-cell approach to HIV vaccines

To advance underdeveloped approaches to designing a preventive HIV vaccine, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, is launching a new program to foster the study of B cells, immune cells that can produce antibodies with the capacity to neutralize HIV.

20 May 2008

Nanoworms target tumors

By linking strings of spherical iron oxide nanoparticles and coating the resulting construct with a biocompatible polymer, a multi-institutional research team has created "nanoworms" that can better target tumors and produce stronger magnetic resonance imaging (MRI) signals than their component nanoparticles. The nanoworms also appear to be a promising vehicle for carrying anticancer drugs into tumors. The researchers published their work in the journal Advanced Materials.

20 May 2008

Dendrimers improve imaging with magnetic nanoparticles

Dendrimers are spherical polymer nanoparticles that have shown promise as targeted anticancer drug delivery vehicles. Iron oxide nanoparticles have already demonstrated the ability to image tumors and metastatic lesions.

20 May 2008

Counting immune cells on a 'protein printboard'

In order to monitor how far an HIV infection has progressed, the number of immune cells - lymphocytes - must be counted. Researchers at the University of Twente have developed a method that neatly arranges the antibodies that bind to these immune cells on a 'molecular printboard'. The researchers are publishing this key step in the road towards antibody-based sensors in the Journal of the American Chemical Society (JACS).

20 May 2008

Primate model for autism

A primate model for autism using the U.S. children's immunization schedule was unveiled at the International Meeting For Autism Research (IMFAR) this weekend.

20 May 2008

First-born children are at higher risk of developing asthma and allergies due to pregnancy conditions

First-born children are at higher risk of developing asthma and allergy because of different conditions they experience in the uterus, according to new research from the Isle of Wight in the United Kingdom, which will be presented at the American Thoracic Society's 2008 International Conference in Toronto on Wednesday, May 21.

20 May 2008

Farming mothers may help children beat allergies

Mothers exposed to farms, particularly to barns and farm milk, while pregnant confer protection from allergies on their newborns, according to a group of German researchers, who will present their findings at the American Thoracic Society's 2008 International Conference in Toronto on Wednesday, May 21.

20 May 2008

Warning about lack of attention given to hepatitis

A report by the World Hepatitis Alliance has called for an increased focus on hepatitis and says the disease should be given the same attention as AIDS, tuberculosis and malaria.

20 May 2008