Immune System News and Research

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EpiCept announces opinion by European Regulatory Authority on Ceplene

EpiCept Corporation has announced that the European Committee for Medicinal Products for Human Use (CHMP), the scientific committee of the European Medicines Agency (EMEA), has issued, as expected following the trend vote announced last month, a negative opinion regarding the marketing authorization application (MAA) for Ceplene (histamine dihydrochloride) for the remission maintenance and prevention of relapse of patients with Acute Myeloid Leukemia (AML) in first remission.

24 Mar 2008

WHO warns Aussies to prepare for deadly flu

The World Health Organisation (WHO) is warning Australians to prepare for a potentially deadly flu season.

23 Mar 2008

Skin patch gives bird flu vaccine a big boost

Researchers testing an experimental skin patch designed to boost an H5N1 vaccine say preliminary results have been promising.

21 Mar 2008

Asthma medicines often not prescribed as guidelines recommend

More than a decade after national guidelines were issued for asthma treatment, some patients still don't receive prescriptions for the inhalers that experts say offer the safest and most effective long-term control of the disease, a new study suggests.

20 Mar 2008

Cell transplant dramatically changes diabetic's life

Experimental cell plant transplantation has dramatically changed the life of a diabetic woman.

19 Mar 2008

The effect of melatonin on colitis

In rats with experimental colitis, the marked increase in bacterial translocation in postcolitis rats has been reversed by melatonin administration.

19 Mar 2008

Survival mechanism of T lymphocytes uncovered

When an individual is challenged by a virus, a bacterium or any other infectious agent, several classes of white blood cells are being activated in order to fight the invasion.

19 Mar 2008

New interventional radiology treatment shows promise for complications from bone marrow, stem cell tranplants

The standard treatment to treat graft-versus-host disease (GVHD) after bone marrow or cord blood transplant is intravenous (IV) steroids that alter the immune response; however, it is not always effective and failure results in very high mortality.

19 Mar 2008

Do bacterial combinations result in enhanced cytokine production? No!

Probiotic bacteria, defined as living microorganisms that have beneficial effects on human health, have been used for the prevention and treatment of a diverse range of disorders.

19 Mar 2008

Discovery alters long standing concept of fixed protein structure

The thousands of proteins found in nature are simply strings of amino acids, assembled by genes, and scientists have long believed that they automatically fold themselves into uniquely fixed, 3-dimensional shapes to fire the engine of life.

19 Mar 2008

Sex, age, burn site associated with abnormal scarring after burn injury

Sex, age, burn site, number of surgical procedures and the type of skin graft are associated with abnormal scarring following burns, according to a report in the March/April 2008 issue of Archives of Facial Plastic Surgery, one of the JAMA/Archives journals.

18 Mar 2008

New information on HIV genetic switch

If the battle against HIV, the virus that causes AIDS, is a chess match, then new research published today gives new insight into one of the virus' most important moves.

18 Mar 2008

New understanding of rare immune disorder called Job's syndrome

Scientists have made another major breakthrough--the second in the past year--in understanding a rare immune disorder called Job's syndrome.

18 Mar 2008

New discovery alters longstanding concept of fixed protein structure

18 Mar 2008

Gene network disrupted by obesity

According to new research an entire network of genes in the body is disrupted by overeating and this not only causes obesity, but also diabetes and heart disease.

17 Mar 2008

New chemical can kill latent tuberculosis bacteria

Success in the laboratory suggests that a new compound can point the way to preventing active tuberculosis in people infected with the latent form of the bacterium, says a team led by researchers at Weill Cornell Medical College in New York City.

17 Mar 2008

Modified virus vaccine shows promise in mouse model of breast cancer

Researchers have shown that vaccinating mice with a modified form of a virus containing proteins from breast cancer cells can kill large breast cancer tumors and tumors that have spread to the lungs.

17 Mar 2008

Investigational drug Debio-025 tested for preventing muscle fiber death in muscular dystrophy

An investigational antiviral drug currently undergoing human trials in Europe for treating Hepatitis C infections may have potential to reduce muscle cell damage in Duchenne and other forms of muscular dystrophy (MD).

17 Mar 2008

How diabetes drives atherosclerosis

Researchers have discovered how diabetes, by driving inflammation and slowing blood flow, dramatically accelerates atherosclerosis, according to research to be published in the March 14 edition of the journal Circulation Research. Experts once believed that atherosclerosis, or hardening of the arteries, developed when too much cholesterol clogged arteries with fatty deposits called plaques.

14 Mar 2008