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New CAR T cell therapy shows promise for treating advanced thyroid cancer

A new chimeric antigen receptor (CAR) T cell therapy called AIC100, which targets the ICAM-1 protein, demonstrated encouraging responses and an acceptable safety profile in patients with two types of advanced thyroid cancer, according to researchers from The University of Texas MD Anderson Cancer Center.

29 Apr 2025

$Innovative CAR-T cell therapy achieves remarkable results in patients with refractory CD30+ lymphoma$

Innovative CAR-T cell therapy achieves remarkable results in patients with refractory CD30+ lymphoma

Researchers from the Sant Pau Research Institute (IR Sant Pau), in collaboration with Sant Pau Hospital and the Josep Carreras Leukaemia Research Institute, have developed an innovative CAR-T cell therapy targeting the CD30 protein (HSP-CAR30), which has shown high efficacy in patients with refractory CD30+ lymphoma.

29 Apr 2025

Researchers uncover how substance use accelerates brain aging

In a comprehensive Genomic Press Interview, researchers from UTHealth Houston have uncovered crucial evidence that substance use disorders (SUDs) accelerate biological aging in the brain through distinct molecular mechanisms.

29 Apr 2025

Researchers discover new biomarker to predict multiple sclerosis progression

Researchers at the University of Turku, Finland, have discovered a new biomarker that can predict the progression of multiple sclerosis (MS).

29 Apr 2025

Perceived stress linked to worsened symptoms in COPD patients

Increased perceived stress may cause worsened respiratory symptoms and decreased quality of life in people with chronic obstructive pulmonary disease (COPD), according to a new study.

29 Apr 2025

As a diversity grant dies, young scientists fear it will haunt their careers

Adelaide Tovar, a University of Michigan scientist who researches genes related to diabetes, used to feel like an impostor in a laboratory. Tovar, 32, grew up poor and was the first in her family to graduate from high school. During her first year in college, she realized she didn't know how to study.

29 Apr 2025

A journey through science, software, and innovation: Insights from the Bruker software team

Follow Bruker's experts as they discuss the SCRUM approach to software development in the scientific industry.

From Bruker Daltonics 29 Apr 2025

Routine molecular monitoring doubles survival in high-risk AML subtypes

A highly sensitive bone marrow test could double survival rates for some groups of younger adults with Acute Myeloid Leukemia (AML) by helping doctors identify if they might relapse up to three months earlier.

29 Apr 2025

Metrion Biosciences launches NaV1.9 high-throughput screening assay to strengthen screening portfolio and advance research on new medicines for pain

Metrion Biosciences ("Metrion"), the specialist preclinical contract research organization (CRO) and a global leader in ion channel services, today announced the launch of its validated, high-throughput NaV1.9 screening assay to advance discovery and development of novel pain therapeutics.

28 Apr 2025

Dopamine circuit helps the brain unlearn fear

Dangers come but dangers also go and when they do, the brain has an "all-clear" signal that teaches it to extinguish its fear.

28 Apr 2025

Simple urine sample could revolutionize early prostate cancer diagnosis

A newly published study involving researchers from Karolinska Institutet indicates that prostate cancer can be diagnosed at an early stage through a simple urine sample.

28 Apr 2025

Influenza virus hijacks human gene regulator to evade immune system

The influenza virus manipulates the body's gene regulation system to accelerate its own spread, according to researchers at the University of Gothenburg.

28 Apr 2025

Researchers discover dual role of sleep in memory formation

Memory formation, storage, and retrieval are fundamental processes that define who we are and how we interact with the world.

28 Apr 2025

Anti-inflammatory drug can prevent and alleviate periodontal tissue damage

A recent study reveals that dimethyl fumarate (DMF), a compound already approved for other inflammatory diseases, can prevent and alleviate periodontal tissue damage.

28 Apr 2025

Immunotherapy replaces surgery for early-stage dMMR cancers in landmark study

Neoadjuvant PD-1 blockade with dostarlimab achieved high rates of organ preservation in patients with early-stage mismatch repair-deficient (dMMR) solid tumors across multiple types. Most patients avoided surgery with durable disease control, reshaping potential cancer treatment pathways.

28 Apr 2025

Arc Institute expands virtual cell atlas with industry partnerships

Arc Institute continues its work to generate and share large-scale, high-quality datasets of cell state before and after chemical or genetic perturbations to enable "virtual cell" models and other innovations.

28 Apr 2025

Targeted drug zongertinib shows strong results for HER2-mutant lung cancer in clinical trial

The HER2-targeted therapy zongertinib demonstrated clinical benefits for previously treated patients with advanced HER2-mutant non-small cell lung cancer – particularly those with specific HER2 mutations – with manageable side effects, according to results from the Phase Ia/Ib Beamion LUNG-1 trial led by researchers from The University of Texas MD Anderson Cancer Center.

28 Apr 2025

New topical gel reduces painful rash from colorectal cancer treatment

Researchers from the UCLA Health Jonsson Comprehensive Cancer Center and The University of Texas MD Anderson Cancer Center have demonstrated that a novel topical BRAF inhibitor gel called LUT014 significantly reduces the severity of an acne-like rash, a common and painful side effect experienced by patients undergoing anti-EGFR therapies for colorectal cancer.

28 Apr 2025

Adaptive NK cells can effectively target ovarian cancer, study shows

Researchers at Karolinska Institutet have uncovered a unique ability of a special subtype of natural killer cells in the immune system, called adaptive NK cells, to remember ovarian tumors and effectively attack them.

28 Apr 2025