Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Restoring cholesterol levels could be a new therapeutic approach for diseases linked to TDP-43 protein

Researchers in Singapore have discovered that brain cells cannot maintain the cholesterol-rich myelin sheath that protects and insulates neurons in the absence of a protein called TDP-43.

4 Aug 2021

Eating more plant-based foods associated with lower risk of cardiovascular disease in midlife

Eating more nutritious, plant-based foods is heart-healthy at any age, according to two research studies published today in the Journal of the American Heart Association, an open access journal of the American Heart Association.

4 Aug 2021

Open-access database could speed up repurposing of old drugs as new treatments

Researchers have created a new open-access database of information on drug candidates and how they are metabolized by the body, which could help speed up the repurposing of old drugs as new treatments.

3 Aug 2021

Study finds a significant link between statins and survival rates of triple-negative breast cancer patients

A study led by researchers from The University of Texas MD Anderson Cancer Center found a significant association between cholesterol-lowering drugs commonly known as statins and survival rates of triple-negative breast cancer patients. Since statins are low in cost, easy to access and produce minimal side effects, this could have an important impact on outcomes for this aggressive disease.

3 Aug 2021

Analysis: Keto diets place pregnant women and kidney disease patients at risk of adverse health effects

In the most comprehensive analysis yet of ketogenic (keto) diets, a review in Frontiers in Nutrition finds keto diets place pregnant women and kidney disease patients at risk of adverse health effects.

3 Aug 2021

UVA researchers overturn conventional wisdom on action of key hormone receptors within cells

Researchers at the University of Virginia School of Medicine have overturned conventional wisdom on the workings of vital hormone receptors within cells, a finding that could boost drug development for diabetes and related metabolic disorders, cancer and other diseases.

31 Jul 2021

People with metabolic syndrome may be at higher risk for second stroke, death

People with larger waistlines, high blood pressure and other risk factors that make up metabolic syndrome may be at higher risk for having a second stroke and even dying than people who do not have metabolic syndrome, according to a meta-analysis published in the July 28, 2021, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Jul 2021

Nine of ten patients with hypertension do not receive enough treatment

Hypertension (high blood pressure) is the leading treatable cause of illness and death worldwide. More than a billion people are hypertensive, defined as having blood pressure (BP) with a systolic level (the higher number) of at least 140 millimeters of mercury (mmHg) or diastolic level (the lower number) of 90 mmHg or higher.

28 Jul 2021

Machine learning models that include social determinants of health better predict cardiovascular outcomes

Machine learning can accurately predict cardiovascular disease and guide treatment--but models that incorporate social determinants of health better capture risk and outcomes for diverse groups, finds a new study by researchers at New York University's School of Global Public Health and Tandon School of Engineering.

27 Jul 2021

Researchers identify an unexpected effect for already characterized active substances

Every innovative drug starts with the search for an active substance targeting key players in disease-related processes.

23 Jul 2021

'Good cholesterol' protects the liver from inflammation and injury, study shows

The body's so-called good cholesterol may be even better than we realize. New research from Washington University School of Medicine in St. Louis suggests that one type of high-density lipoprotein (HDL) has a previously unknown role in protecting the liver from injury.

22 Jul 2021

Researchers identify immune protein linked to rare neurodegenerative disease

UT Southwestern researchers have identified an immune protein tied to the rare neurodegenerative condition known as Niemann-Pick disease type C.

21 Jul 2021

Patient's case report reveals link between Bell’s palsy and Pfizer-BioNTech vaccine

The case of a patient who experienced two facial palsies – one after the first and another after the second dose of the Pfizer-BioNTech COVID-19 vaccine – strongly suggests that Bell’s palsy (facial nerve palsy of unknown cause) is linked to the Pfizer-BioNTech vaccine, doctors write in the journal BMJ Case Reports.

19 Jul 2021

New statement highlights the role of primary care professional in caring for people with stroke

The new scientific statement, "Primary Care of Adult Patients After Stroke," acknowledges the importance of primary care in the system of care for patients with stroke, summarizing the available literature and providing a roadmap for holistic, goal-directed and patient-centered care.

15 Jul 2021

COVID-19 researchers review 184 drug repurposing candidates

New research describes the use of integrative bioinformatics analyses of transcriptomic profiles for COVID-19 therapeutics.

15 Jul 2021

Is niclosamide a potential SARS-CoV-2 antiviral inhibitor?

Niclosamide is an antihelminthic drug, historically used to treat tapeworm infestations, though has been investigated and repurposed for use against SARS-CoV-2. In a new study recently uploaded to the preprint server bioRxiv* by Garrett et al. (July 12, 2021), the drug demonstrates the ability to reorganize the lipid profile of SARS-CoV-2 infected Vero E6 cells, thereby limiting virus replication.

14 Jul 2021

Whole grain consumption may reduce risk factors of heart disease as we age

Middle- to older-aged adults who ate at least three servings of whole grains daily had smaller increases in waist size, blood pressure, and blood sugar levels over time compared to those who ate less than one-half serving per day, according to new research.

13 Jul 2021

Mice study identifies pathways that link high-fat diet to atherosclerosis

It's long been known that a high-fat diet can lead to clogged arteries, but we have only recently begun to learn in detail how the process works. A new study in experimental mice could go a long way to finding treatments to keep arteries open and flowing.

9 Jul 2021

Strawberries could improve cardiometabolic risk factors in at-risk adults

Whole berries have long been known for their extended health benefits. This has largely been due to their high fiber and polyphenol profile, as well as their low energy (calorie) contributions to daily diets.

8 Jul 2021

Discovery of blood biomarker opens new perspectives for dietary prevention of AMD-related risks

Age-related macular degeneration (AMD) is the principal cause of vision loss in industrialised countries, with nearly 20 million people affected in Europe in 2020. Although identified as a risk factor, until now it was impossible to evaluate retinal omega-3 fatty acid deficits.

30 Jun 2021

Cholesterol News and Research

Further Reading

Restoring cholesterol levels could be a new therapeutic approach for diseases linked to TDP-43 protein

Eating more plant-based foods associated with lower risk of cardiovascular disease in midlife

Open-access database could speed up repurposing of old drugs as new treatments

Study finds a significant link between statins and survival rates of triple-negative breast cancer patients

Analysis: Keto diets place pregnant women and kidney disease patients at risk of adverse health effects

UVA researchers overturn conventional wisdom on action of key hormone receptors within cells

People with metabolic syndrome may be at higher risk for second stroke, death

Nine of ten patients with hypertension do not receive enough treatment

Machine learning models that include social determinants of health better predict cardiovascular outcomes

Researchers identify an unexpected effect for already characterized active substances

'Good cholesterol' protects the liver from inflammation and injury, study shows

Researchers identify immune protein linked to rare neurodegenerative disease

Patient's case report reveals link between Bell’s palsy and Pfizer-BioNTech vaccine

New statement highlights the role of primary care professional in caring for people with stroke

COVID-19 researchers review 184 drug repurposing candidates

Is niclosamide a potential SARS-CoV-2 antiviral inhibitor?

Whole grain consumption may reduce risk factors of heart disease as we age

Mice study identifies pathways that link high-fat diet to atherosclerosis

Strawberries could improve cardiometabolic risk factors in at-risk adults

Discovery of blood biomarker opens new perspectives for dietary prevention of AMD-related risks

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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