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Researchers identify mechanism responsible for spatial issues in people with Down syndrome

Researchers reveal that an imbalance of gene Grik1 is behind the spatial issues that people with Down syndrome experience.

11 Sep 2019

Cell adhesion protein promotes metastasis in breast cancer, study reveals

Researchers at the Johns Hopkins Kimmel Cancer Center discovered that a cell adhesion protein, E-cadherin, allows breast cancer cells to survive as they travel through the body and form new tumors, a process termed metastasis.

From Johns Hopkins Medicine 11 Sep 2019

'Protein mapping' approach reveals why metastatic melanoma patients do not respond to immunotherapy

Tel Aviv University and Sheba Medical Center researchers say they have discovered why more than half of patients with metastatic melanoma do not respond to immunotherapy cancer treatments.

10 Sep 2019

Researchers investigate how to prevent the onset of schizophrenia using mouse model

Although predisposing processes occur earlier, schizophrenia breaks out at young adulthood, suggesting it might involve a pathological transition during late brain development in predisposed individuals.

9 Sep 2019

Researchers develop new cocktail of drugs that shrink pancreatic tumors

Cancer is relentless and resilient. When a drug blocks a cancer cell's main survival pathway, the cell avoids the obstacle by taking different pathways or detours to save itself. This tactic is called "developing resistance," and it's one of the key challenges researchers face when seeking effective therapeutics to combat pancreatic ductal adenocarcinoma (PDA).

9 Sep 2019

VUMC partners with Batavia to move promising Zika antibody therapy closer to the clinic

Researchers at Vanderbilt University Medical Center are partnering with the Dutch biopharmaceutical firm Batavia Biosciences and Nashville-based IDBiologics to bring to the clinic a highly potent Zika virus neutralizing antibody they isolated three years ago.

6 Sep 2019

Vaping may impair fertility and pregnancy outcomes

E-cigarette usage may impair fertility and pregnancy outcomes, according to a mouse study published in the Journal of the Endocrine Society.

5 Sep 2019

Zika virus damages the adult human brain and impairs memory in mouse model

Zika virus attracted worldwide attention in recent years due to the devastating consequences of infection for pregnant women and their fetuses, many of which were born with microcephaly and other severe neurological malformations.

5 Sep 2019

Resistance to 'hunger hormone' linked with cognitive impairments and memory loss

Scientists at The University of Texas at Dallas have found evidence suggesting that resistance to the "hunger hormone" ghrelin in the brain is linked to the cognitive impairments and memory loss associated with Alzheimer's disease.

4 Sep 2019

New study helps explain why lung tumors turn aggressive

Lung cancer is the number 1 killer among cancers, especially when it is of the non-small cell type. Among these, adenocarcinomas are the most common and aggressive type. These tumors also show a strong tendency to show dedifferentiation, or loss of the features that characterize a mature lung cell.

28 Aug 2019

Scientists identify PoEMs that promote breast cancer metastasis

When breast cancer cells spread through the body, they do so mainly through the lymph system that normally removes excess fluid and waste products from our tissues.

28 Aug 2019

New cellular processes controlling the formation of lymphatic valves found

Lymphedema, resulting from a damaged lymphatic system, can be a debilitating disease in which excess protein-rich fluid (lymph) collects in soft tissues and causes swelling -- most often in the arms or legs.

28 Aug 2019

Study shows microRNA can protect the heart from reperfusion injury

Heart muscle can continue to die even after restoring blood following a heart attack, and scientists have new evidence that one way to help it live is by boosting levels of a tiny RNA that helped the heart form.

27 Aug 2019

Remodeling unhealthful gut microbiomes with the help of synthetic peptides

You are what you eat - right down to the microbiome living in your gut. Diet can affect which microbes are in the intestinal tract, and research has shown that harmful gut microbiome changes can lead to illnesses such as heart disease, obesity and cancer.

27 Aug 2019

Salk researchers develop new gene-editing tool to target broad range of mutations, cell types

The ability to edit genes in living organisms offers the opportunity to treat a plethora of inherited diseases. However, many types of gene-editing tools are unable to target critical areas of DNA, and creating such a technology has been difficult as living tissue contains diverse types of cells.

26 Aug 2019

New study reveals exosome-mediated communication between mother and baby

During pregnancy, the mother and the baby communicate in a variety of ways. For instance, signals from the fetus are crucially involved in the initiation of labor and delivery.

22 Aug 2019

Enzyme induced by stress associated with liver cancer growth

An enzyme induced by stress to help reduce production of damaging free radicals is also used by liver cancer to regulate two major cell proliferation pathways that enable the cancer to thrive, scientists report.

22 Aug 2019

Meat allergy triggered by tick bites explained

Researchers from University of Virginia School of Medicine have uncovered the mystery behind development of allergic reactions to red meat such as beef in some individuals. Recently there has been a body of research on allergies to meat developing in individuals due to tick bites.

21 Aug 2019

Next generation of hydrogel systems could help repair bone defects in future

Bioengineers and dentists from the UCLA School of Dentistry have developed a new hydrogel that is more porous and effective in promoting tissue repair and regeneration compared to hydrogels that are currently available.

20 Aug 2019

Study: Blocking inflammatory pathway could prevent melanoma brain metastasis

Brain metastases are among the deadliest tumor metastases, with a median survival period of less than one year, and the incidence of brain metastasis is rising.

20 Aug 2019