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Novel approach uses patient's cells as "trojan horse" to target lung cancer cells

Lung cancer is not the most common form of cancer, but it is by far the deadliest.

23 Feb 2024

Gut microbial metabolite plays a role in exacerbating thrombosis

A gut microbial metabolite called 2-methylbutyrylcarnitine (2MBC) plays a role in exacerbating thrombosis -- the formation of blood clots – researchers report February 23rd in the journal Cell Metabolism.

23 Feb 2024

New study defines clinical phenotype of Post-infectious ME/CFS, highlighting unique biomarker insights

The pathophysiological mechanisms of PI myalgic encephalitis/chronic fatigue syndrome (ME/CFS).

23 Feb 2024

Natural killer cells lead the charge in cancer treatment innovation

Review synthesizes research on NK cells' role in cancer immunity and their potential in therapeutics through bioengineering, immune checkpoint inhibitors, and cell engagers, highlighting ongoing preclinical and clinical trials.

22 Feb 2024

Females' immune system edges out males but at a cost of higher autoimmune risk

A review article highlights how two X chromosomes in females influence immune system composition and function, leading to faster infection clearance and stronger vaccination responses but also a higher risk of autoimmune diseases.

22 Feb 2024

Elevated IFN-γ levels linked to long COVID, study finds

Researchers find elevated IFN-γ levels in long COVID patients, with symptom improvement correlating with decreased IFN-γ, suggesting it as a potential biomarker and target for therapeutic intervention.

22 Feb 2024

New immunotherapy target activin receptor 1C shows promise against cancer

Drugs that target a receptor on immune cells called activin receptor 1C may combat tumor-induced immune suppression and help patients' immune systems fight back against cancer, according to a study by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

22 Feb 2024

MD Anderson acquires cell therapy safety technology from Bellicum Pharmaceuticals

The University of Texas MD Anderson Cancer Center today announced it has acquired certain assets from Bellicum Pharmaceuticals, Inc. related to the CaspaCIDe switch platform and the GoCAR platform.

22 Feb 2024

Delta opioid receptor agonist reduces anxiety-like behavior in mice

Anxiety-related disorders can have a profound impact on the mental health and quality of life of affected individuals.

22 Feb 2024

Proper serum levels of vitamin D may have a protective effect against breast cancer

The impact of vitamin D on breast cancer (BC).

22 Feb 2024

Vitamin D3 and phytochemicals team up for immune boost and aging defense, study finds

Review highlights the synergistic effects of vitamin D3 and phytochemicals in promoting immune balance, reducing inflammation, supporting gut health, and combating aging, emphasizing the importance of these nutrients for longevity and vitality.

21 Feb 2024

CPRIT awards MD Anderson 16 grants to support cancer research and prevention

The University of Texas MD Anderson Cancer Center today was awarded 16 grants totaling over $25.5 million from the Cancer Prevention and Research Institute of Texas (CPRIT) in support of cancer screening, early detection and prevention programs, faculty recruitment, and groundbreaking cancer research across all areas of the institution.

21 Feb 2024

Unlocking non-hormonal male contraception with HDAC inhibitors

Surveys show most men in the United States are interested in using male contraceptives, yet their options remain limited to unreliable condoms or invasive vasectomies.

20 Feb 2024

Unlocking sulfasalazine's mechanism of action in IBD-SpA patients

Although it is one of the oldest medications used to treat patients with inflammatory bowel disease (IBD) and an effective treatment for an associated arthritis condition called spondyloarthritis (SpA), sulfasalazine's mechanism of action has been unclear.

20 Feb 2024

Missing gut microbes after antibiotics and a high-fat diet may be to blame for sugar-free candy and gum giving you gas

A recent Cell study showed how a high-fat diet and antibiotic exposure could trigger sorbitol intolerance by depleting Clostridia from the gut microbiota.

20 Feb 2024

Study provides evidence that antidepressant use in pregnancy affects child's brain development

A new study explored synapse maturation in the PFC of mice when exposed to 5-HT, shedding light on the link between the chemical and future behavioral changes.

19 Feb 2024

New study pinpoints key markers for Long COVID diagnosis

Study identifies elevated serologic responses and memory CD8+ T cell clonal expansion as key markers of Long COVID, offering insights into its pathology and potential diagnostic approaches.

18 Feb 2024

Innovative immunotherapy targets rare melanoma subtypes

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have built and demonstrated the potential efficacy of a new chimeric antigen receptor (CAR) T-cell-based immunotherapy specifically designed to treat patients with cutaneous and rare subtypes of melanoma.

16 Feb 2024

Study suggests CT imaging with automated AI system predicts EGFR genotype, identifying mutation status cost-effectively and non-invasively

Researchers developed an artificial intelligence (AI)-based predictive system (AIPS) model for the early detection of lung cancer by combining radiological, clinical, and genetic data.

16 Feb 2024

City of Hope cures oldest person of blood cancer and achieves HIV remission

City of Hope, one of the largest cancer research and treatment organizations in the United States, treated the oldest person to be cured of a blood cancer and then achieve remission for HIV after receiving a blood stem cell transplant from a donor with a rare genetic mutation.

15 Feb 2024

Receptor News and Research

Novel approach uses patient's cells as "trojan horse" to target lung cancer cells

Gut microbial metabolite plays a role in exacerbating thrombosis

New study defines clinical phenotype of Post-infectious ME/CFS, highlighting unique biomarker insights

Natural killer cells lead the charge in cancer treatment innovation

Females' immune system edges out males but at a cost of higher autoimmune risk

Elevated IFN-γ levels linked to long COVID, study finds

New immunotherapy target activin receptor 1C shows promise against cancer

MD Anderson acquires cell therapy safety technology from Bellicum Pharmaceuticals

Delta opioid receptor agonist reduces anxiety-like behavior in mice

Proper serum levels of vitamin D may have a protective effect against breast cancer

Vitamin D3 and phytochemicals team up for immune boost and aging defense, study finds

CPRIT awards MD Anderson 16 grants to support cancer research and prevention

Unlocking non-hormonal male contraception with HDAC inhibitors

Unlocking sulfasalazine's mechanism of action in IBD-SpA patients

Missing gut microbes after antibiotics and a high-fat diet may be to blame for sugar-free candy and gum giving you gas

Study provides evidence that antidepressant use in pregnancy affects child's brain development

New study pinpoints key markers for Long COVID diagnosis

Innovative immunotherapy targets rare melanoma subtypes

Study suggests CT imaging with automated AI system predicts EGFR genotype, identifying mutation status cost-effectively and non-invasively

City of Hope cures oldest person of blood cancer and achieves HIV remission

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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