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Duke engineers develop technique to make artificial arteries that produce biochemical signals

Duke engineers have developed a technique to make artificial arteries that naturally produce biochemical signals vital to their functions. The technique is also ten times faster than current methods for tissue engineering of blood vessels.

19 Feb 2016

Study provides new insights into Retigabine drug

A study published ahead of print in the The Journal of General Physiology has revealed new insights into Retigabine, a known pharmacological treatment for epilepsy.

19 Feb 2016

Parvus' novel therapeutic approach employing nanomedicines published in Nature

Parvus Therapeutics today announced the publication in Nature of a seminal paper describing the discovery and applications of a novel therapeutic approach employing nanomedicines, referred to as "Navacims"TM, to reprogram white blood cells to become regulatory cells capable of blunting autoimmune responses and restoring the equilibrium of the immune system.

19 Feb 2016

New semi-automated sample method facilities extraction of urine samples for LC-MS/MS analysis

INTEGRA, in conjunction with DPX Labs LLC, has produced an application note that describes a novel high throughput semi-automated sample method for processing urine samples ready for drugs of abuse analysis by LC-MS/MS.

From INTEGRA Biosciences 19 Feb 2016

Clot-busting drugs decrease mortality in one of worst forms of hemorrhagic stroke

The use of clot-busting drugs to clear blood from the brain's ventricles may be the first effective strategy to decrease mortality for a type of catastrophic bleeding stroke, according to phase-3 clinical trial results announced Thursday at the International Stroke Conference in Los Angeles.

19 Feb 2016

DEK gene present in plasma can help predict outcomes for patients with head and neck cancer

Researchers at the University of Cincinnati have discovered that a human cancer-causing gene, called DEK, can be detected in the plasma of head and neck cancer patients. DEK may help doctors understand how a person's immune system could be used to treat cancer or predict outcomes for patients.

18 Feb 2016

New method could help scientists better predict disease-causing mutations in people's genes

Two researchers at the University of Tennessee, Knoxville, have developed a method that could help clinicians and scientists better predict which mutations in people's genes could cause a disease and which would remain dormant.

18 Feb 2016

Revealing dynamic protein complexes with NMR: an interview with Elisar Barbar

Most proteins are involved in interactions with one or a few functional ligands, but some proteins, like light chain 8 (LC8), have numerous binding partners. LC8 interacts with more than 100 functionally different proteins, from viral proteins to motor proteins to proteins involved in cell division.

From Bruker BioSpin Group 18 Feb 2016

Researchers make some progress in determining causes for glioblastoma multiforme

A research team, with the participation of the University of Granada (UGR), has made some progress in determining the causes for glioblastoma multiforme (GBM), one of the most aggressive brain tumors known, to be resistant to the drugs currently used, which is one of the main limitations of its treatment.

18 Feb 2016

Findings offer new approach to treating metabolic disorders

A new research study has revealed an important relationship between proteins secreted by the heart and obesity, glucose intolerance, and insulin resistance. The findings, published today in Obesity, offer a new approach to treating metabolic disorders, including type 2 diabetes, by targeting the pathway that controls the proteins' concentration in the blood.

18 Feb 2016

Combining pain medicine with metal ions could destroy drug-resistant cancer cells

Fighting chemoresistant cancer remains a huge challenge that scientists are tackling from as many angles as they can. One alternative approach involves pairing two groups of compounds -- pain medicine and metal ions -- that have individually shown promise as anti-cancer agents. Scientists report in the ACS journal Inorganic Chemistry that combining the two led to new compounds that could destroy drug-resistant cancer cells and leave most normal cells alone in lab tests.

18 Feb 2016

New drug combination shows promise for patients with non-small cell lung cancer

Lung cancer is the most common cause of cancer-related death in the United States resulting in more than 158,000 deaths each year. With a 5-year survival rate at only 18 percent, the development of new and improved treatment options is needed.

18 Feb 2016

FDA issues new guidance to reduce risk of Zika blood transmission

As a safety measure against the emerging Zika virus outbreak, today the U.S. Food and Drug Administration issued a new guidance recommending the deferral of individuals from donating blood if they have been to areas with active Zika virus transmission, potentially have been exposed to the virus, or have had a confirmed Zika virus infection.

18 Feb 2016

Beiging of white fat could be harnessed to combat diabetes

Researchers are getting closer to learning how to turn white fat cells into brown fat cells, in a process called "beiging," to bring down blood sugar levels and fight diabetes. The team, led by Joseph Baur, PhD, an assistant professor of Physiology in the Perelman School of Medicine at the University of Pennsylvania published their findings this month in the journal Diabetes.

18 Feb 2016

American Pain Society releases new post-surgical pain management guideline

The American Pain Society has released a new evidence-based clinical practice guideline, appearing in The Journal of Pain, with 32 recommendations to help clinicians achieve optimal pain management following surgery. According to numerous studies, the majority of surgical patients receive inadequate pain relief, which can heighten the risk for prolonged post-surgical pain, mood disorders and physical impairment.

18 Feb 2016

Drugs News and Research

Duke engineers develop technique to make artificial arteries that produce biochemical signals

Study provides new insights into Retigabine drug

Parvus' novel therapeutic approach employing nanomedicines published in Nature

New semi-automated sample method facilities extraction of urine samples for LC-MS/MS analysis

Clot-busting drugs decrease mortality in one of worst forms of hemorrhagic stroke

DEK gene present in plasma can help predict outcomes for patients with head and neck cancer

New method could help scientists better predict disease-causing mutations in people's genes

Revealing dynamic protein complexes with NMR: an interview with Elisar Barbar

Researchers make some progress in determining causes for glioblastoma multiforme

Findings offer new approach to treating metabolic disorders

Combining pain medicine with metal ions could destroy drug-resistant cancer cells

New drug combination shows promise for patients with non-small cell lung cancer

FDA issues new guidance to reduce risk of Zika blood transmission

Beiging of white fat could be harnessed to combat diabetes

American Pain Society releases new post-surgical pain management guideline

Promising phase II results for ozanimod in MS

Studies explore causative factor of hypertension in younger, obese men and women

Benefit of using antibody-coated drug-eluting stents for CHD still unclear, shows report

Small chemical change to existing antibacterial drug may result in better treatment for TB

Small peptide TAxI holds promise for carrying biologic drugs into spinal cord

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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