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A single round of chemotherapy has no effect on sperm count, say researchers

Men with early-stage testicular can safely undergo one round of post-operative chemotherapy or radiotherapy without a long-term negative effect on sperm count.

25 Feb 2019

Scientists identify cause of devastating pediatric brain disorder

An international effort led by physician-scientists at Rady Children's Institute for Genomic Medicine, in collaboration with a team at the Montreal Children's Hospital of the McGill University Health Centre, has identified the cause of a devastating pediatric brain disorder paving the way for the first step in developing potential therapies for this rare neurodegenerative condition.

25 Feb 2019

New analysis highlights increasing focus of early-stage clinical trials on rare cancers

The proportion of early-stage drug trials tackling the biggest cancer killers has declined sharply since the early 1990s as less common tumor types receive increasing attention, according to new research to be presented during the International Congress on Targeted Anticancer Therapies 2019, taking place from today to 27 February in Paris, France.

25 Feb 2019

Obesity and severe obesity added as risk factors for premature heart disease in children

Obesity and severe obesity in childhood and adolescence have been added to the list of conditions that put children and teens at increased risk for premature heart disease, according to a new scientific statement from the American Heart Association published in the Association's journal Circulation.

25 Feb 2019

Base Pair Biotechnologies to develop point-of-care tests for opioids in newborns

Base Pair Biotechnologies announced today the receipt of a Fast Track Small Business Innovation Research grant from the National Institute on Drug Abuse of the NIH

From Base Pair Biotechnologies, Inc. 25 Feb 2019

Sperm quality not affected by one course of postoperative treatment for early testicular cancer

Men with early stage testicular cancer can safely receive one course of chemotherapy or radiotherapy after surgery without it having a long-term effect on their sperm count, according to a study published in the leading cancer journal Annals of Oncology today (Monday).

25 Feb 2019

New form of hereditary osteoporosis identified

A research group headed by Professor Outi Mäkitie, Unviersity of Helsinki, identified in families with childhood-onset osteoporosis disease-causing mutations in a gene that had previously not been connected with the skeletal system or osteoporosis.

25 Feb 2019

Researchers create new method to ensure integrity of clinical trials data with blockchain

UC San Francisco researchers have created a proof-of-concept method for ensuring the integrity of clinical trials data with blockchain.

23 Feb 2019

Researchers find increased rates of CRC screening in Kentucky after Medicaid expansion

Kentucky is one of the poorest states in the U.S. However, the state has been one of the most successful in reducing its uninsured rate, which happened in part through the Affordable Care Act's Medicaid expansion that took effect on January 1, 2014.

23 Feb 2019

Study unravels genetic basis of hypertrophic cardiomyopathy cases in Finland

One third of hypertrophic cardiomyopathy cases in Finland are caused by one of the four major mutations, a new study from the University of Eastern Finland and Kuopio University Hospital shows.

23 Feb 2019

Researchers investigate how marijuana and tobacco co-use affects quit attempts by smokers

Tobacco isn't the only thing being smoked in the Deep South, and for many, it's only half of their habit.

23 Feb 2019

Researchers unravel how specific intestinal microbiota amplify inflammatory reactions in the lungs

The composition of the microbiome - the countless bacteria, fungi and viruses that colonize our body surface, skin, intestines or lungs - makes a decisive contribution to human health or disease.

23 Feb 2019

Study finds modest decrease in burnout among physicians

The epidemic levels of physicians reporting burnout dropped modestly in 2017, according to a study by researchers at the Stanford University School of Medicine, the Mayo Clinic and the American Medical Association.

23 Feb 2019

A simple change can drastically reduce unnecessary tests for urinary tract infections

Tests to detect urinary tract infections (UTI) often are performed routinely in hospitals, even when patients don't have symptoms.

22 Feb 2019

ICHE’s reviews on surgical infections, unnecessary urine tests, and nurses' role in antibiotic stewardship

Changes to standard urine orders in a computer physician order entry (CPOE) system, resulted in a 45% reduction in unnecessary urine cultures ordered, a change that is expected prevent unnecessary treatment of asymptomatic patients whose bacteria counts are above normal.

22 Feb 2019

CT and Doppler equipment have low accuracy in detecting cerebral vasospasm and ischemia

Both CT angiography and transcranial Doppler have limited accuracy in detecting cerebral vasospasm and predicting delayed cerebral ischemia in patients with subarachnoid hemorrhage due to ruptured aneurysm, reports a study in the inaugural edition of Critical Care Explorations, the official open-access journal of the Society of Critical Care Medicine.

22 Feb 2019

New identified biomarker predicts patients who might benefit from HER2-targeted agents

In an effort to further individualize therapy and avoid over-treating patients, researchers at the Johns Hopkins Kimmel Cancer Center report a new study using PET scans has identified a biomarker that may accurately predict which patients with one type of HER2-positive breast cancer might best benefit from standalone HER2-targeted agents, without the need for standard chemotherapy.

22 Feb 2019

New app reliably determines physicians' skills in forming accurate, efficient diagnoses

Assessing the accuracy and value of an increasingly popular and free online patient management app, researchers at Johns Hopkins Medicine and other institutions say that physicians with more training and experience perform better in selecting appropriate diagnoses for sample patient scenarios.

22 Feb 2019

Researchers use radio-telemetry to track the habitats of bottlenose dolphins

Using telemetry units in hospitals to monitor patient health is standard practice. Now, a similar approach is proving to be invaluable for dolphins, too.

22 Feb 2019

Vitamin D supplementation less effective in the presence of obesity, shows study

A new Journal of Bone and Mineral Research study confirms that vitamin D supplementation is less effective in the presence of obesity, and it uncovers a biological mechanism to explain this observation.

21 Feb 2019

Hospital News and Research

A single round of chemotherapy has no effect on sperm count, say researchers

Scientists identify cause of devastating pediatric brain disorder

New analysis highlights increasing focus of early-stage clinical trials on rare cancers

Obesity and severe obesity added as risk factors for premature heart disease in children

Base Pair Biotechnologies to develop point-of-care tests for opioids in newborns

Sperm quality not affected by one course of postoperative treatment for early testicular cancer

New form of hereditary osteoporosis identified

Researchers create new method to ensure integrity of clinical trials data with blockchain

Researchers find increased rates of CRC screening in Kentucky after Medicaid expansion

Study unravels genetic basis of hypertrophic cardiomyopathy cases in Finland

Researchers investigate how marijuana and tobacco co-use affects quit attempts by smokers

Researchers unravel how specific intestinal microbiota amplify inflammatory reactions in the lungs

Study finds modest decrease in burnout among physicians

A simple change can drastically reduce unnecessary tests for urinary tract infections

ICHE’s reviews on surgical infections, unnecessary urine tests, and nurses' role in antibiotic stewardship

CT and Doppler equipment have low accuracy in detecting cerebral vasospasm and ischemia

New identified biomarker predicts patients who might benefit from HER2-targeted agents

New app reliably determines physicians' skills in forming accurate, efficient diagnoses

Researchers use radio-telemetry to track the habitats of bottlenose dolphins

Vitamin D supplementation less effective in the presence of obesity, shows study

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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