Central Nervous System News and Research

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Pre-clinical study demonstrates positive effects of advanced prebiotic on neuro-inflammation, anxiety

Clasado Biosciences Limited, the producers and suppliers of the second generation prebiotic Bimuno(R) (B-GOS), a unique trans-galactooligosaccharide, and the Department of Psychiatry, University of Oxford, today announce the results of their latest pre-clinical study demonstrating a major role of the unique carbohydrate complex Bimuno against neuro-inflammation and anxiety.

28 Oct 2015

ARN announces availability of comprehensive guide for rehabilitation nursing practice

The Association of Rehabilitation Nurses is pleased to announce the availability of the eagerly awaited The Specialty Practice of Rehabilitation Nursing: A Core Curriculum, 7th Edition. The Core Curriculum serves as the foundation for the rehabilitation nursing profession and can be applied to the many diverse settings and roles, including acute rehabilitation, post-acute care, community settings, skilled nursing homes, case management, research facilities, consulting academia, and clinics.

26 Oct 2015

University of Louisville professor wins 2015 Elizabeth McWilliams Miller Award for Excellence in Research

M. Cynthia Logsdon, Ph.D., WHNP-BC, FAAN, Professor, University of Louisville, School of Nursing and Associate Chief of Nursing for Research, University of Louisville Hospital has won the 2015 Elizabeth McWilliams Miller Award for Excellence in Research from Sigma Theta Tau International, the honor society of nursing.

24 Oct 2015

Endocannabinoids can affect development of baby's pancreas

According to the latest research results from the Medical University of Vienna, endocannabinoids, cannabis-like substances produced by the body itself, can affect the development of a baby's pancreas. The study also highlights the importance of diet during pregnancy for the foetal pancreas to form.

23 Oct 2015

Study shows promise for developing targeted treatments for multiple sclerosis

Modern scientific understanding has considered multiple sclerosis (MS) to be a disease controlled by the T cell, a type of white blood cell. Research has shown that in MS, T cells inappropriately attack myelin, the protective layer of fat covering nerves in the central nervous system, exposing them to damage.

23 Oct 2015

Study shows how dietary fatty acids affect development and progression of multiple sclerosis

Dietary fatty acids affect the development and progression of autoimmune chronic-inflammatory diseases such as multiple sclerosis. In a collaborative study between the Departments of Neurology at the Ruhr-Universität Bochum (St. Josef-Hospital) and the Friedrich Alexander Universtiy Erlangen, researchers now found that long-chain fatty acids promote the development and propagation of CNS reactive immune cells in the intestinal wall. On the contrary, short-chain fatty acids promote the development and propagation of regulatory cells in the immune system.

22 Oct 2015

Sprout announces U.S. availability of Addyi for HSDD treatment in premenopausal women

Sprout Pharmaceuticals, Inc., a division of Valeant Pharmaceuticals North America LLC, announced today that Addyi, a once-daily, non-hormonal pill for the treatment of acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women, is now available in the United States through certified physicians and pharmacies.

19 Oct 2015

Discovery may provide noninvasive approach to assessing toxic effects of anesthetic agents in children

Could looking at the eyes provide a new way of studying how anesthesia affects the developing brain? The retinas of immature mice exposed to one widely used general anesthetic show evidence of "programmed cell death," or apoptosis, reports a study in Anesthesia & Analgesia.

19 Oct 2015

Study suggests combination of MMF and CNIs can protect against rare lymphoma

16 Oct 2015

Genomic analysis confirms sexual transmission of Ebola virus in Liberia

A suspected case of sexual transmission of Ebola virus disease (EVD) in Liberia was confirmed using genomic analysis, thanks to in-country laboratory capabilities established by U.S. Army scientists in collaboration with the Liberian Institute for Biomedical Research (LIBR).

16 Oct 2015

Researchers report weak association between brain size and IQ

As early as 1836, the German physiologist and anatomist Friedrich Tiedemann, in an article in the Philosophical Transactions, expressed his opinion that "there is undoubtedly a connection between the absolute size of the brain and the intellectual powers and functions of the mind". With the advent of brain imaging methods (e.g., MRI, PET), reliable assessments of in-vivo brain volume and investigations of its association with IQ are now possible.

15 Oct 2015

Researchers link organ transplant drug to rise in rare lymphoma

A study led by Johns Hopkins researchers has linked the immunosuppressive drug mycophenolate mofetil (MMF) to an increased risk of central nervous system (CNS) lymphoma in solid organ transplant patients. But the same study also found that another class of immunosuppressive drugs, called calcineurin inhibitors (CNIs), given alone or in combination with MMF, appears to protect transplant patients against this rare form of lymphoma.

15 Oct 2015

FDA permits marketing of first CSF nucleic acid-based test for detection of multiple pathogens

The U.S. Food and Drug Administration today allowed marketing of the first cerebrospinal fluid (CSF) nucleic acid-based test for simultaneous detection of multiple pathogens that can cause central nervous system infections.

12 Oct 2015

AGS releases updated, expanded Beers Criteria to improve medication use in older adults

The American Geriatrics Society today released its second updated and expanded Beers Criteria--lists of potentially inappropriate medications for older adults who are not receiving hospice or palliative care, and one of the most frequently cited reference tools in the field of geriatrics.

12 Oct 2015

Bionomics, Merck extend collaboration to develop drug candidates for treatment of chronic and neuropathic pain

Bionomics Limited, a biopharmaceutical company focused on the discovery and development of innovative therapeutics for the treatment of diseases of the central nervous system (CNS) and cancer, today announced that it has extended its strategic collaboration with Merck & Co., Inc., Kenilworth NJ., (known as MSD outside the United States and Canada) for the discovery and development of drug candidates for the treatment of chronic and neuropathic pain.

8 Oct 2015

Multicenter study shows Monteris’ NeuroBlate System improves outcome in brain tumor patients

Monteris Medical today announced recent data demonstrating that newly diagnosed brain tumor patients undergoing procedures with the NeuroBlate System, a minimally invasive robotic laser thermotherapy tool, experienced improved outcomes.

1 Oct 2015

AMO Pharma raises $25 million in private equity financing

AMO Pharma Limited, a privately held biopharmaceutical company focusing on debilitating diseases with limited or no treatment options, announced today that the company has raised $25 million in private equity financing from Woodford Investment Management.

30 Sep 2015

Predicting better immunotherapy response, neurological outcomes in adults with autoimmune cerebellar ataxia

While autoimmune cerebellar ataxia (a loss of muscle control coordination) can lead to severe disability with some patients becoming wheelchair-bound, there are factors that may help predict better immunotherapy response, according to the Mayo Clinic study published by JAMA Neurology.

30 Sep 2015

Disruption of blood-CSF barrier may negatively affect progression of Alzheimer's disease

More and more data from preclinical and clinical studies strengthen the hypothesis that immune system-mediated actions contribute to and drive pathogenesis in Alzheimer's disease. The team of Roosmarijn Vandenbroucke in the Claude Libert Group (VIB/UGent) combined their knowledge and expertise related to inflammation with the expertise in Alzheimer's disease present in the Bart De Strooper Group (VIB/KU Leuven).

29 Sep 2015

Study: Increased acetylation of histones promotes fear extinction in mice

The targeted modulation of gene activity and cellular signaling pathways could provide a new approach to the treatment of fear and anxiety states according to the recent findings of a project sponsored by the Austrian Science Fund FWF.