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New vitamin K-based drug eliminates medication-resistant epileptic seizures in mice

In the cover article of the June 11 issue of the Journal of Medicinal Chemistry, a team of researchers at the Medical University of South Carolina, led by Sherine Chan, Ph.D., and James Chou, Ph.D., reports that a new vitamin K-based drug has proved effective in mouse models of medication-resistant seizures.

6 Jul 2020

New approach could illuminate a critical stage in the life cycle of P. vivax malaria parasite

A new approach could illuminate a critical stage in the life cycle of one of the most common malaria parasites.

3 Jul 2020

Repurposed drug for acute lung injury in COVID-19

Now, a new study addresses the possible use of an FDA-approved monoclonal antibody, called fostamatinib, a spleen tyrosine kinase inhibitor (SYK), to reduce the levels of mucin-1, a molecule associated with acute lung injury and acute respiratory distress syndrome (ARDS). People who have severe COVID-19 disease may develop ARDS.

2 Jul 2020

Common asthma drug may offer potential as treatment for Alzheimer's disease

A new study reveals that the common asthma drug salbutamol may offer potential as a treatment for Alzheimer's disease.

1 Jul 2020

Novel drug could protect the brain during and after stroke

Neuroscientists at the University of Pittsburgh Brain Institute have identified a novel drug that could protect the brain during and after a stroke.

1 Jul 2020

Study: Even moderate exercise during pregnancy boosts benefits of breastmilk for babies

A new study led by researchers at The Ohio State University Wexner Medical Center and College of Medicine finds even moderate exercise during pregnancy increases a compound in breast milk that reduces a baby's lifelong risks of serious health issues such as diabetes, obesity and heart disease.

1 Jul 2020

Researchers develop biomedical device for use in regenerative medicine

The UPV/EHU-University of the Basque Country has developed a sustainable biomedical device from food industry by-products for use in regenerative medicine

1 Jul 2020

Alzheimer’s drug could be re-purposed to reverse blood vessel damage in diabetes

Drugs that were developed to treat Alzheimer’s Disease could be re-purposed to prevent - or even reverse - the damage done to the blood vessels in people who are obese or suffer from type 2 diabetes, according to new research.

1 Jul 2020

Irresistin: a ‘poison arrow’ to defeat antibiotic resistance

News-Medical speaks to Dr. James Martin and Dr. Zemer Gitai from Princeton University about their research which led to the discovery of a new antibiotic.

1 Jul 2020

GIRK channel activator can provide potential treatments for brain disorders

Potassium channels play an important role in controlling the electrical activity of neurons in the brain.

1 Jul 2020

Research uncovers malaria's secret to surviving in the blood

New research from the Francis Crick Institute has found how the malaria parasite protects itself from toxic compounds in red blood cells.

30 Jun 2020

Breast milk even more beneficial for baby if mother exercises regularly, finds study

A new study from the Ohio State University Wexner Medical Centre shows that if breastfeeding mothers exercise regularly, they may end up providing more beneficial breast milk. Exercise is known to benefit individuals in various ways, and this new study shows that there are probably more advantages to exercising than previously known.

29 Jun 2020

Innovative technology permits faster, cheaper toxicological screening of drug candidates

Ramot at Tel Aviv University has signed a collaboration agreement with Bayer to develop and validate a platform for in vitro cardiotoxicity screening, using human heart tissues 3D-printed in Prof. Tal Dvir's Laboratory for Tissue Engineering and Regenerative Medicine at Tel Aviv University.

29 Jun 2020

New steroid compounds from deep-water starfish show anticancer activity

Russian scientists from Far Eastern Federal University, G. B. Elyakov Pacific Institute of Bioorganic Chemistry, and A.V. Zhirmunsky National Scientific Center for Marine Biology have discovered four new steroid substances which target cells of human breast cancer, and colorectal carcinoma.

26 Jun 2020

Synoicum adareanum shows new possibilities for developing melanoma-specific drug

Could the cure for melanoma - the most dangerous type of skin cancer - be a compound derived from a marine invertebrate that lives at the bottom of the ocean?

26 Jun 2020

New method spurs production of antibiotic or antiparasitic compounds in actinobacteria

Researchers have developed a method to spur the production of new antibiotic or antiparasitic compounds hiding in the genomes of actinobacteria, which are the source of drugs such as actinomycin and streptomycin and are known to harbor other untapped chemical riches.

25 Jun 2020

Promising treatment does not guard against complication in type 1 diabetes

Historically, half or more of people with type 1 diabetes develop kidney disease, which frequently progresses to kidney failure requiring hemodialysis or a kidney transplant for survival.

25 Jun 2020

G6PD enzyme offers a promising therapeutic target in autoimmune diseases

A team from the University of Valencia, the La Fe Hospital Health Research Institute, and the INCLIVA Institute have participated in the identification of an enzyme (G6PD) as a possible therapeutic target in autoimmune diseases or in controlling exacerbated inflammatory responses such as the one caused by SARS-CoV-2 infection.

25 Jun 2020

High deductible health plans are widening racial health gaps, study says

First-of-its-kind study finds that black cancer survivors on these plans are far more likely to struggle to afford health care and medicine than their white counterparts, while black and white cancer survivors on other types of plans are equally unlikely to face these challenges.

24 Jun 2020

New study to analyze risks posed by heat wave and COVID-19

As the United States nears its hottest time of the year, scientists are launching a research project into whether the public health impacts of extreme heat will be amplified by the COVID-19 pandemic.

23 Jun 2020

Compound News and Research

New vitamin K-based drug eliminates medication-resistant epileptic seizures in mice

New approach could illuminate a critical stage in the life cycle of P. vivax malaria parasite

Repurposed drug for acute lung injury in COVID-19

Common asthma drug may offer potential as treatment for Alzheimer's disease

Novel drug could protect the brain during and after stroke

Study: Even moderate exercise during pregnancy boosts benefits of breastmilk for babies

Researchers develop biomedical device for use in regenerative medicine

Alzheimer’s drug could be re-purposed to reverse blood vessel damage in diabetes

Irresistin: a ‘poison arrow’ to defeat antibiotic resistance

GIRK channel activator can provide potential treatments for brain disorders

Research uncovers malaria's secret to surviving in the blood

Breast milk even more beneficial for baby if mother exercises regularly, finds study

Innovative technology permits faster, cheaper toxicological screening of drug candidates

New steroid compounds from deep-water starfish show anticancer activity

Synoicum adareanum shows new possibilities for developing melanoma-specific drug

New method spurs production of antibiotic or antiparasitic compounds in actinobacteria

Promising treatment does not guard against complication in type 1 diabetes

G6PD enzyme offers a promising therapeutic target in autoimmune diseases

High deductible health plans are widening racial health gaps, study says

New study to analyze risks posed by heat wave and COVID-19

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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