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Breakthrough menopause drug for hot flashes and night sweats gains FDA approval

The federal Food and Drug Administration today approved a new menopause drug that reduces hot flashes and night sweats after the drug was successfully tested at UVA Health and other sites in the United States and around the world.

24 Oct 2025

Enhancing early diagnosis of developmental delays in Pennsylvania's children

Children who are mistreated at a young age are more likely to experience a wide range of developmental delays and health problems, according to Christian Connell, Ken Young Family Professor in Healthy Children and professor of human development and family studies at Penn State.

24 Oct 2025

Researchers reveal how maternal stress reshapes fetal growth and brain development

Maternal stress, encompassing physical, emotional, and psychological distress, remains a widespread yet underestimated risk during pregnancy.

24 Oct 2025

Boston Children's Hospital secures $8.1M for spastic paraplegia research

Boston Children's Hospital has received $8.1M in NIH funding to support and expand the Spastic Paraplegia Centers of Excellence Research Network (SP-CERN). Darius Ebrahimi-Fakhari, M.D., Ph.D., Director of the Movement Disorders Program at Boston Children's, and his team will lead this multi-center effort.

24 Oct 2025

Advancements and clinical translation of intelligent nanodrugs for breast cancer treatment

A comprehensive review in "Biofunct. Mater." meticulously details the most recent advancements and clinical translation of intelligent nanodrugs for breast cancer treatment.

24 Oct 2025

New database transforms evidence-based care for children with lower respiratory tract infections

Lower respiratory tract infections (LRTIs) remain the most common illnesses in children, accounting for up to two-thirds of pediatric outpatient and inpatient cases in China.

24 Oct 2025

Leveraging the power of T cells for more effective and durable cancer immunotherapies

T cells play central roles in the adaptive immune response against cancer. Their functional inactivation is a primary driver of tumor progression, making the reactivation of T cell function a main goal in immunotherapy.

24 Oct 2025

Advancements in organoids could transform treatment of spinal cord injury and peripheral nerve injury

A recent review published in Engineering explores the construction and potential applications of spinal cord and peripheral nerve organoids for regenerative medicine in neurotrauma.

24 Oct 2025

Revolutionizing lipid nanoparticle formulations for targeted treatments

Lipid nanoparticles (LNPs) are the delivery vehicles of modern medicine, carrying cancer drugs, gene therapies and vaccines into cells.

24 Oct 2025

Researchers uncover and inhibit a key cell death pathway in severe cutaneous adverse reactions

A collaborative research group led by Haruna Kimura (graduate student), Dr. Akito Hasegawa (Assistant Professor), and Prof. Riichiro Abe from the Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, together with Prof. Takemasa Ozawa from the Department of Chemistry, School of Science, The University of Tokyo, and Dr. Yoichi Ogawa (Lecturer) from the Department of Dermatology, Faculty of Medicine, University of Yamanashi, has developed a novel therapeutic candidate that may improve the prognosis of severe cutaneous adverse reactions such as Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).

24 Oct 2025

Psilocybin and mindfulness offer new hope for depressive healthcare workers

Frontline healthcare workers struggling with depression after the COVID-19 pandemic experienced significant relief from a treatment combining psilocybin group therapy with mindfulness training, according to a new study from Huntsman Mental Health Institute at University of Utah Health.

23 Oct 2025

Breakthrough combo therapy lowers death risk in recurrent prostate cancer

Men whose prostate cancer returns after surgery or radiation therapy may now benefit from a new drug combination shown in clinical trials to cut the risk of death by more than 40%.

23 Oct 2025

How COVID mRNA vaccines may make cancer treatments more effective

Researchers found that COVID-19 mRNA vaccines, when given within 100 days of starting immune checkpoint inhibitors, were linked to significantly longer survival in lung and melanoma cancer patients. The vaccines trigger a powerful type-I interferon response that primes tumors to become more responsive to immunotherapy.

23 Oct 2025

Les Turner Symposium on ALS brings researchers and clinicians to discuss new research findings

The 15th annual Les Turner Symposium on ALS will be held on Monday, Nov. 3, 2025 in Chicago. Hosted by the Les Turner ALS Foundation and the Les Turner ALS Center at Northwestern Medicine, this event will gather leading ALS researchers and clinicians to discuss the latest research and perspectives on the disease.

23 Oct 2025

Cervical cancer patients treated with radiation and chemotherapy report greater short-term decline in quality of life

A new study co-led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that women with early-stage cervical cancer who received radiation plus chemotherapy reported a greater short-term decline in quality of life compared to those who received radiation alone.

23 Oct 2025

Loneliness interventions can be effective but do not yet offer a complete solution

Interventions designed to reduce loneliness can be effective, but do not yet offer a complete solution to what is becoming a worldwide public health problem, according to research published by the American Psychological Association.

23 Oct 2025

International experts publish guidelines on the administration of gene therapy for hereditary hearing loss

Up to 60% of congenital and early-onset hearing loss is caused by genetic mutations in an inherited gene, and gene therapy has recently emerged as a potential treatment option.

23 Oct 2025

Antibody discovery could provide new treatment options for aggressive breast cancers

A new potential antibody therapy strategy which restricts the growth of treatment-resistant breast cancers has been developed by scientists.

23 Oct 2025

Biodesix announces expanded Bio-Rad Laboratories partnership agreement to develop Droplet Digital™ PCR high complexity assays

Biodesix, Inc., a leading diagnostics solutions company, today announced the signing of an expanded partnership agreement under which Biodesix will conduct the development, clinical validation, and regulatory submissions of in vitro diagnostic (IVD) assays to enable highly sensitive detection of multiple genomic markers focused on oncology applications, utilizing Bio-Rad's Droplet Digital™ PCR (ddPCR™) technology on Bio-Rad's QX600 platform.

23 Oct 2025

Disruption of glial circadian rhythms linked to Alzheimer's disease progression

Alzheimer's disease is notorious for scrambling patients' daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease.

23 Oct 2025

Therapy News and Research

Breakthrough menopause drug for hot flashes and night sweats gains FDA approval

Enhancing early diagnosis of developmental delays in Pennsylvania's children

Researchers reveal how maternal stress reshapes fetal growth and brain development

Boston Children's Hospital secures $8.1M for spastic paraplegia research

Advancements and clinical translation of intelligent nanodrugs for breast cancer treatment

New database transforms evidence-based care for children with lower respiratory tract infections

Leveraging the power of T cells for more effective and durable cancer immunotherapies

Advancements in organoids could transform treatment of spinal cord injury and peripheral nerve injury

Revolutionizing lipid nanoparticle formulations for targeted treatments

Researchers uncover and inhibit a key cell death pathway in severe cutaneous adverse reactions

Psilocybin and mindfulness offer new hope for depressive healthcare workers

Breakthrough combo therapy lowers death risk in recurrent prostate cancer

How COVID mRNA vaccines may make cancer treatments more effective

Les Turner Symposium on ALS brings researchers and clinicians to discuss new research findings

Cervical cancer patients treated with radiation and chemotherapy report greater short-term decline in quality of life

Loneliness interventions can be effective but do not yet offer a complete solution

International experts publish guidelines on the administration of gene therapy for hereditary hearing loss

Antibody discovery could provide new treatment options for aggressive breast cancers

Biodesix announces expanded Bio-Rad Laboratories partnership agreement to develop Droplet Digital™ PCR high complexity assays

Disruption of glial circadian rhythms linked to Alzheimer's disease progression

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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