Immune System News and Research

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Volunteers in AIDS vaccine trial may be at greater risk of infection

Following the aborting of two international trials of an experimental AIDS vaccine, thousands of volunteers have been told the vaccine may have actually raised their risk of infection.

14 Nov 2007

Placenta uses a cloaking device similar to that used by parasites

The placenta uses a cloaking device similar to that used by parasites to avoid detection by the mother's immune system. MRC funded scientists looking to develop a diagnostic test for pre-eclampsia, a major and potentially fatal cause of fetal and maternal illness, made the amazing discovery which could have far reaching implications.

13 Nov 2007

New genetic lineage of Ebola virus discovered in great apes

The Zaire species of Ebolavirus (ZEBOV) remains the most virulent of the various known species. It alone is responsible for 88% of human deaths from haemorrhagic fever recorded since Ebola's discovery in 1976.

13 Nov 2007

Most UK citizens susceptible to hep B infection

The failure of the UK to introduce universal hepatitis B immunisation means that most UK citizens are susceptible to infection, warns an infectious diseases expert in this week's BMJ.

13 Nov 2007

Anti-inflammation molecule helps fight MS-like disease

An immune system messenger molecule that normally helps quiet inflammation could be an effective tool against multiple sclerosis (MS). Neurology researchers led by Abdolmohamad Rostami, M.D., Ph.D., professor and chair of the Department of Neurology at Jefferson Medical College of Thomas Jefferson University and the Jefferson Hospital for Neuroscience in Philadelphia, have found that the protein interkeukin-27 (IL-27) helped block the onset or reverse symptoms in animals with an MS-like disease.

13 Nov 2007

Factor key to severity of community-associated methicillin-resistant staph infections identified

Newly described proteins in drug-resistant strains of the Staphylococcus aureus bacterium attract and then destroy protective human white blood cells - a key process ensuring that S. aureus survives and causes severe disease, according to scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

13 Nov 2007

Antivirals reduce deaths from flu in hospitalized patients

Adults with influenza infections serious enough to require hospitalization are much less likely to die from the disease if they are given antiviral medications, according to a new study published in the December 15 issue of Clinical Infectious Diseases, currently available online.

13 Nov 2007

Could a new vaccine be the key to stopping Alzheimer's disease?

A new study from the Oklahoma Medical Research Foundation (OMRF) shows that immunization could offer a way to blunt or even prevent the deadly, memory-robbing disease.

13 Nov 2007

Abnormal immune cells may cause unprovoked idiopathic anaphylaxis

Two new clinical reports shed light on why some people suffer from recurrent episodes of idiopathic anaphylaxis--a potentially life-threatening condition of unknown cause characterized by a drop in blood pressure, fainting episodes, difficulty in breathing, and wheezing.

13 Nov 2007

Seattle Post-Intelligencer examines reactions of people who participated in Merck's canceled HIV vaccine

The Seattle Post-Intelligencer on Friday examined the reaction of volunteers in the Seattle arm of Merck's recently halted HIV vaccine trial. According to the Post-Intelligencer, participants who were interviewed on the condition of anonymity have voiced "decidedly mixed feelings" about participating in the trial because of safety concerns (Paulson, Seattle Post-Intelligencer, 11/9).

12 Nov 2007

Newly completed genome sequence may provide new treatment options for dandruff

Scientists from P&G Beauty announced that they successfully sequenced the complete genome for Malassezia globosa (M. globosa) , a naturally occurring fungus responsible for the onset of dandruff and other skin conditions in humans.

6 Nov 2007

Researchers neutralise the HIV virus

With the latest advances in treatment, doctors have discovered that they can successfully neutralise the HIV virus.

6 Nov 2007

Lungs' pressure needn't threaten heart transplant survival

Heart surgeons at Johns Hopkins say people who need heart transplants can largely avoid transplant failure due to elevated blood pressure in their lungs with the help of proper drug treatment.

6 Nov 2007

Inflammation causes insulin resistance not obesity

Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered that inflammation provoked by immune cells called macrophages leads to insulin resistance and Type 2 diabetes.

6 Nov 2007

Bavarian Nordic updates on vaccine project pipeline

In a business update, Danish-based biopharmaceutical company Bavarian Nordic, reported a number of developments in its vaccine project pipeline.

6 Nov 2007

BCG vaccine causing illness, death among HIV-positive infants, report says

The BCG vaccine, which aims to prevent tuberculosis among children in developing countries, might be causing illness and death among some HIV-positive infants, researchers said on Friday, the Los Angeles Times reports.

6 Nov 2007

Common painkillers may prevent Parkinson's disease

Researchers in the U.S. are suggesting that painkillers such as ibuprofen and naproxen can cut the risk of Parkinson's disease by as much as 60%.

6 Nov 2007

Blood-incompatible infant heart transplants safe, may save more lives

ABO-incompatible heart transplantation (heart transplantation among non-compatible blood groups) can be safely performed in infants a year old or younger, researchers reported at the American Heart Association's Scientific Sessions 2007.

6 Nov 2007

Osteopontin-c is a good biomarker of breast cancer.

Researchers have identified a molecule that may be more accurate than existing biological signposts used to predict which breast cancers will develop into advanced forms of the disease.

6 Nov 2007

Medical causes of iatrogenic renal disorders

Nephrologists and other health care providers need to be aware of certain medications and diagnostic test preparations that, in some patients, can cause damage to the kidneys, according to a special clinical update being presented at the American Society of Nephrology's 40th Annual Meeting and Scientific Exposition in San Francisco.

5 Nov 2007