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U.S. Marshals seize nearly 90,000 bottles of dietary supplements containing kratom

The U.S. Food and Drug Administration announced today that U.S. Marshals, at the agency's request, seized nearly 90,000 bottles of dietary supplements labeled as containing kratom. The product, manufactured for and held by Dordoniz Natural Products LLC, located in South Beloit, Illinois, is marketed under the brand name RelaKzpro and worth more than $400,000.

7 Jan 2016

Drexel biomedical engineer identifies immune cell as potential strategy for growing blood vessels

In what could be a pivotal step toward repairing non-healing wounds and damaged organs, a Drexel University biomedical engineer has identified an immune cell as a potential strategy for growing blood vessels.

7 Jan 2016

CUMC study reveals statins may help reduce heart disease risk in people with sleep apnea

A new study conducted at Columbia University Medical Center has revealed some of the underlying mechanisms that may increase the risk of heart disease in people with sleep apnea. The study also found that statins -- the cholesterol-lowering medications commonly prescribed to combat heart disease -- may help reverse this process.

7 Jan 2016

Discovery may pave way for more effective treatments for pandemics, seasonal flu

Scientists at Imperial College London have discovered how flu viruses 'hijack' cell machinery when they infect the body. The findings, published in the journal Nature, may pave the way for more effective antiviral treatments for pandemics and for seasonal flu, which infects over 800 million people worldwide every year.

7 Jan 2016

Statins could be effective against metastatic small cell lung cancer

In a recent study, researchers at Cancer Treatment Centers of America at Western Regional Medical Center (Western), in collaboration with international colleagues, found that statins could be an effective therapeutic against metastatic small cell lung cancer (SCLC).

7 Jan 2016

More than half of primary care physicians provide nonessential specialty referrals upon patient request

A study recently published in the American Journal of Managed Care found that more than half of primary care providers reported that they made what they considered unnecessary referrals to a specialist because patients requested it. Many physicians said they yielded to patient requests for brand-name drug prescriptions when cheaper generics were available.

7 Jan 2016

Leukaemia drug could slow progression of Duchenne muscular dystrophy

A drug commonly used to treat leukaemia is showing potential as a treatment that could slow the progression of the muscle-wasting condition, Duchenne muscular dystrophy.

6 Jan 2016

Rani Therapeutics, MedImmune collaborate to evaluate novel oral drug delivery platform

Rani Therapeutics announced today that it has entered into a collaboration with MedImmune, the global biologics research and development arm of AstraZeneca, to evaluate Rani's novel oral drug delivery platform. The companies have agreed to conduct feasibility studies over the next two years, in which Rani will test select biologic molecules in the area of metabolic disease to evaluate the oral delivery of these molecules.

6 Jan 2016

DURECT reports successful completion of DUR-928 Phase 1 study for acute use indications

DURECT Corporation today announced the successful completion of a Phase 1 clinical trial with an injectable formulation of DUR-928 intended for acute use indications. DUR-928 is an endogenous, small-molecule, new chemical entity (NCE), which may have broad applicability in metabolic diseases such as nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH), and in acute organ injuries such as acute kidney injury (AKI).

6 Jan 2016

Vtesse receives FDA's Breakthrough Therapy designation for VTS-270

Vtesse, Inc. announced today that the U.S. Food and Drug Administration has granted its drug candidate, VTS-270 for treatment of Niemann-Pick Type C1 Disease (NPC), Breakthrough Therapy designation status. Both the FDA and the European Medicines Agency (EMA) had previously granted Orphan Drug status to VTS-270, which is currently in a pivotal Phase 2b/3 clinical trial.

6 Jan 2016

Buprenorphine superior to methadone in reducing duration of treatment for babies born in drug withdrawal

A study of two opioids used to wean babies born in withdrawal from drugs their mothers have taken shows that buprenorphine is superior to methadone in reducing duration of treatment and length of hospital stay.

6 Jan 2016

Researchers identify mechanism that allows cancer cells to grow rapidly when blood sugar levels rise

Researchers have identified a mechanism that allows cancer cells to respond and grow rapidly when levels of sugar in the blood rise. This may help to explain why people who develop conditions in which they have chronically high sugar levels in their blood, such as obesity, also have an increased risk of developing certain types of cancer.

6 Jan 2016

UC San Diego School of Medicine study compares payments among different specialties

The Physician Payments Sunshine Act, passed under the Affordable Care Act, requires all pharmaceutical and medical device companies to report payments to physicians, including consulting fees, gifts, speaking fees, meals, travel and research grants. This information is searchable to the public on a database called Open Payments, managed by the Centers for Medicare & Medical Services.

6 Jan 2016

Lipoprotein nanoplatelets important for imaging biological molecules and cells

An interdisciplinary research team from the University of Illinois at Urbana-Champaign has developed a new material composite derived from quantum dots. These lipoprotein nanoplatelets are rapidly taken up by cells and retain their fluorescence, making them particularly well-suited for imaging cells and understanding disease mechanisms.

6 Jan 2016

New report raises questions about potential risks of chromium therapies

Chromium supplements are widely consumed for their antidiabetic activity as chromium(III) enhances the insulin sensitivity of cells. In particular, orthomolecular practitioners believe in the beneficial effects of providing the body with extra amounts of essential trace elements.

6 Jan 2016

Purified cannabinoid reduces seizures in children and young adults with treatment-resistant epilepsy

Children and young adults with severe forms of epilepsy that does not respond to standard antiepileptic drugs have fewer seizures when treated with purified cannabinoid, according to a multi-center study led by researchers from UCSF Benioff Children's Hospital San Francisco.

6 Jan 2016

Using antidepressant drug during first trimester of pregnancy may increase risk of birth defects

Using paroxetine--a medication prescribed to treat conditions including depression, obsessive-compulsive disorder, anxiety and posttraumatic stress disorder--during the first trimester of pregnancy may increase newborns' risk of congenital malformations and cardiac malformations. That's the conclusion of a recent analysis published in the British Journal of Clinical Pharmacology.

6 Jan 2016

Millendo signs license agreement, secures funding to test new drugs for treatment of endocrine disorders

Millendo Therapeutics, a University of Michigan startup company, announced an exclusive license agreement with AstraZeneca for the worldwide development and commercialization rights to test a new compound, MLE4901, for the treatment of polycystic ovary syndrome.

6 Jan 2016

FDA permits Sound Pharmaceuticals to start SPI-1005 clinical trial for treatment of Meniere's Disease

Sound Pharmaceuticals is pleased to announce that it began enrolling a clinical trial to test SPI-1005 in the treatment of Meniere's Disease (MD). MD or idiopathic endolymphatic hydrops is an inner ear disease that involves episodic vertigo, sensorineural hearing loss, and tinnitus.

5 Jan 2016

Epigenetics in Drug Discovery

Chromatrap®, a business unit of Porvair Sciences, has announced that it will be the Lead Sponsor at the prestigious “Epigenetics in Drug Discovery” conference to be held in Cambridge, UK from 26th-27th January 2016.

From Chromatrap® - Porvair Sciences Ltd 5 Jan 2016

Drugs News and Research

U.S. Marshals seize nearly 90,000 bottles of dietary supplements containing kratom

Drexel biomedical engineer identifies immune cell as potential strategy for growing blood vessels

CUMC study reveals statins may help reduce heart disease risk in people with sleep apnea

Discovery may pave way for more effective treatments for pandemics, seasonal flu

Statins could be effective against metastatic small cell lung cancer

More than half of primary care physicians provide nonessential specialty referrals upon patient request

Leukaemia drug could slow progression of Duchenne muscular dystrophy

Rani Therapeutics, MedImmune collaborate to evaluate novel oral drug delivery platform

DURECT reports successful completion of DUR-928 Phase 1 study for acute use indications

Vtesse receives FDA's Breakthrough Therapy designation for VTS-270

Buprenorphine superior to methadone in reducing duration of treatment for babies born in drug withdrawal

Researchers identify mechanism that allows cancer cells to grow rapidly when blood sugar levels rise

UC San Diego School of Medicine study compares payments among different specialties

Lipoprotein nanoplatelets important for imaging biological molecules and cells

New report raises questions about potential risks of chromium therapies

Purified cannabinoid reduces seizures in children and young adults with treatment-resistant epilepsy

Using antidepressant drug during first trimester of pregnancy may increase risk of birth defects

Millendo signs license agreement, secures funding to test new drugs for treatment of endocrine disorders

FDA permits Sound Pharmaceuticals to start SPI-1005 clinical trial for treatment of Meniere's Disease

Epigenetics in Drug Discovery

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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