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HPV16 ctDNA assay predicts treatment response in metastatic head and neck cancer

Oncotarget published "Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma" which reported that despite the rising incidence of human papillomavirus related oropharyngeal squamous cell carcinoma, treatment of metastatic disease remains palliative.

2 Aug 2021

Study explains how SARS-CoV-2 variants differ in binding to ACE2 receptor

The current study explored ACE2-RBD interactions with four VoCs including the Alpha, Beta, Gamma, and Delta variants.

29 Jul 2021

New integrative NGS panel for analysis of standard and novel biomarkers in lymphoid neoplasms

Increasing knowledge about genomic biomarkers has facilitated better monitoring and personalized management of patients with B-cell malignant tumors.

29 Jul 2021

Spike-containing virus-like particles induce robust sterilizing immunity against SARS-CoV-2 in macaques

A team of international scientists has recently developed virus-like particles (VLPs) by coating liposomes with the synthetic spike glycoprotein of SARS-CoV-2.

28 Jul 2021

SARS-CoV-2 variants of concern employ different strategies of antibody escape

A recent study in the field of fluid analysis reveals a diverse set of strategies utilized by alpha and beta variants of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) in order to evade antibodies generated during an earlier infection with this virus. The paper is currently available on the bioRxiv* preprint server while it undergoes a peer-review process.

28 Jul 2021

Immunity to SARS-CoV-2 in renal transplant and dialysis patients using Pfizer/BioNTech and Moderna vaccines

A study analyzes the immune responses of medical personnel, as well as immunocompromised DP and immunosuppressed KTR patients.

27 Jul 2021

Impaired immune response to SARS-CoV-2 mRNA vaccination in immunocompromised patients

A new study describes how immunocompromised vaccine recipients may not always respond as expected to the COVID-19 vaccine.

27 Jul 2021

Higher temperatures could limit the spread of dengue infection

Infection with dengue virus makes mosquitoes more sensitive to warmer temperatures, according to new research led by Penn State researchers.

27 Jul 2021

Genomic test may help identify prostate cancer patients at high risk of disease progression

After a biopsy comes back positive for prostate cancer, patients and their doctors are often left with a choice between taking a watch-and-wait approach, known as active surveillance, or proceeding with surgery or radiation.

27 Jul 2021

Monoclonal antibody CT-P59 demonstrates potent antiviral efficacy against SARS-CoV-2 delta variant

A Korean study has recently demonstrated antiviral potency of monoclonal antibody CT-P59 against the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The experiments conducted in animals infected with the delta variant have shown that CT-P59 is able to reduce symptom intensity and viral replication in the respiratory tract. The study is currently available on the bioRxiv* preprint server.

27 Jul 2021

Budesonide’s antiviral effect against SARS-CoV-2

A new study examines the in vitro antiviral effect of pure budesonide and Pulmicort® against the SARS-CoV-2 WT and two VoCs.

26 Jul 2021

A novel interferon-γ release assay for detection of SARS-CoV-2 specific T-cell response

A new study evaluates a commercially available IFN‐γ release assay (IGRA) to determine T-cell responses targeted against SARS-CoV-2.

26 Jul 2021

5.6% seroprevalence of SARS-CoV-2 antibodies in England during second wave

A recent study conducted as a part of the Real-Time Assessment of Community Transmission-2 (REACT-2) program has estimated the seroprevalence of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies among adult populations in England.

25 Jul 2021

Researchers discover camelid-derived two nanobodies that target SARS-CoV-2

A new study has been published on the bioRxiv* preprint server, which has identified and characterized two RBD-targeting neutralizing nanobodies, namely, DL4 and DL28.

23 Jul 2021

Clinical trials during a pandemic – lessons from COVID-19

In this interview, Dr. Benedicte Roquebert, Dr. Stephanie Haim-Boukobza and Dr. Souad Mehlal discuss how COVID-19 has resulted in new ways to think about clinical trials during a pandemic.

From Cerba Research 23 Jul 2021

Researchers identify an unexpected effect for already characterized active substances

Every innovative drug starts with the search for an active substance targeting key players in disease-related processes.

23 Jul 2021

SARS-COV-2 infection leads to neutralizing and protective serological responses in over 70% of DPs

Iain Chapple, University of Birmingham, England, presented the oral session "Longitudinal Serological and Vaccination Responses to SARS-COV-2 in Dental Professionals" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021.

23 Jul 2021

Efficacy of mRNA vaccine-induced memory B cells against SARS-CoV-2 variants

A new study characterizes the functional humoral immunity post-COVID-19 mRNA-based vaccination.

22 Jul 2021

Virginia Tech's in-house development of novel SARS-CoV-2 test shows the power of academic labs

In the early days of the pandemic, scientists at Virginia Tech created a COVID-19 testing laboratory and novel test for the virus from scratch.

21 Jul 2021

New study disproves suspicion that dengue raises risk of zika-related microcephaly

A pregnant woman infected by zika virus does not face a greater risk of giving birth to a baby with microcephaly if she has previously been exposed to dengue virus, according to a Brazilian study that compared data for pregnant women in Rio de Janeiro and Manaus.

20 Jul 2021

Assay News and Research

HPV16 ctDNA assay predicts treatment response in metastatic head and neck cancer

Study explains how SARS-CoV-2 variants differ in binding to ACE2 receptor

New integrative NGS panel for analysis of standard and novel biomarkers in lymphoid neoplasms

Spike-containing virus-like particles induce robust sterilizing immunity against SARS-CoV-2 in macaques

SARS-CoV-2 variants of concern employ different strategies of antibody escape

Immunity to SARS-CoV-2 in renal transplant and dialysis patients using Pfizer/BioNTech and Moderna vaccines

Impaired immune response to SARS-CoV-2 mRNA vaccination in immunocompromised patients

Higher temperatures could limit the spread of dengue infection

Genomic test may help identify prostate cancer patients at high risk of disease progression

Monoclonal antibody CT-P59 demonstrates potent antiviral efficacy against SARS-CoV-2 delta variant

Budesonide’s antiviral effect against SARS-CoV-2

A novel interferon-γ release assay for detection of SARS-CoV-2 specific T-cell response

5.6% seroprevalence of SARS-CoV-2 antibodies in England during second wave

Researchers discover camelid-derived two nanobodies that target SARS-CoV-2

Clinical trials during a pandemic – lessons from COVID-19

Researchers identify an unexpected effect for already characterized active substances

SARS-COV-2 infection leads to neutralizing and protective serological responses in over 70% of DPs

Efficacy of mRNA vaccine-induced memory B cells against SARS-CoV-2 variants

Virginia Tech's in-house development of novel SARS-CoV-2 test shows the power of academic labs

New study disproves suspicion that dengue raises risk of zika-related microcephaly

Understanding the DNA Damage Response in Innate Immunity eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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