Central Nervous System News and Research

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Obstructive hydrocephalus produces significant decrease in brain neurogenesis

In a group of mice, has been identified that their brain presents degenerative changes similar to aging after two months that their cerebrospinal fluid (CSF) stopped circulating normally within the body and starts to accumulate, as reported by a Mexican group of researchers at the University of Colima.

18 Aug 2015

MGH papers reveal the way anesthetics affect brains of older patients and children

Recent Massachusetts General Hospital (MGH) investigations into the neurobiology underlying the effects of general anesthesia have begun to reveal the ways different anesthetic agents alter specific aspects of the brain's electrical signals, reflected by EEG (electroencephalogram) signatures. While those studies have provided information that may lead to improved techniques for monitoring the consciousness of patients receiving general anesthesia, until now they have been conducted in relatively young adult patients.

14 Aug 2015

Amyloid-beta kinetics reveal link between aging and AD risk

Slowed amyloid-beta turnover may explain aging’s association with increased amyloidosis and Alzheimer’s disease, say researchers.

12 Aug 2015

New study launched to find impact of vasculitis on employment, income

The Vasculitis Patient-Powered Research Network and the Vasculitis Clinical Research Consortium launched a study entitled "Impact of vasculitis on employment and income" or "VascWork." The purpose of this study is to learn about the impact of vasculitis on employment and income in patients with different systemic vasculitides.

12 Aug 2015

Structural brain changes found in chemoradiation-treated glioblastoma patients

US researchers find evidence of marked and progressive brain atrophy during standard chemoradiation therapy in patients with glioblastoma.

5 Aug 2015

First drug produced by 3D printing is approved by FDA

Levetiracetam manufactured using three-dimensional (3D) printing has been approved by the US Food and Drug Administration (FDA) for the treatment of epilepsy.

5 Aug 2015

New MS therapies associated with risks and side effects, require active management strategy

Advances in the treatment of Multiple Sclerosis have been good news for patients, but side effects and risks mean that an active management strategy and constant monitoring are essential.

3 Aug 2015

Natural protein fragment produced in the brain can inhibit enzyme implicated in Alzheimer's disease

For the first time, UCLA researchers have shown that a natural protein fragment produced in the brain can act as an inhibitor of a key enzyme implicated in the onset of Alzheimer's disease, a finding that could lead to the development of new drugs to treat the disease.

30 Jul 2015

New analysis examines pharmacy expenditures for publicly insured children with serious chronic illness

In an analysis of expenditures for outpatient pharmacy products used by publicly insured children with serious chronic illness in California, treating hemophilia accounted for about 40 percent of expenditures but included just 0.4 percent of the group studied, suggesting a need to improve pricing for this and other effective yet high-cost medications, according to a study in the July 28 issue of JAMA.

29 Jul 2015

TSRI scientists awarded grant to explore therapeutic potential of protein receptors in Parkinson's disease, other disorders

Scientists from the Florida campus of The Scripps Research Institute have been awarded nearly $1.5 million from the National Institute of General Medical Sciences of the National Institutes of Health to explore the therapeutic potential of a class of proteins that play essential roles in the regulation and maintenance of human health.

28 Jul 2015

Multiple sclerosis relapse management: an interview with Gina Remington

MS relapses are typically reflective of new neurological symptoms. However, it can be a worsening of neurologic symptoms that begins after a patient has been stable (generally for about 30 days), but relapses are persistent and consistent changes in symptoms that occur for more than 24 to 48 hours.

26 Jul 2015

Lupin signs strategic asset purchase agreement with Temmler

Pharma Major Lupin Limited today announced that it has entered into a strategic asset purchase agreement with TEMMLER PHARMA GMBH & CO. KG, a part of the Aenova Group, one of the world's largest pharmaceutical contract manufacturers, to acquire Temmler's specialty product portfolio subject to certain closing conditions.

25 Jul 2015

Body fat can send stress signals, say University of Florida Health researchers

The brain's effect on other parts of the body has been well established. Now, a group that includes two University of Florida Health researchers has found that it's a two-way street: Body fat can send a signal that affects the way the brain deals with stress and metabolism.

24 Jul 2015

MetLife Foundation Awards for Medical Research presented at AAIC 2015

At the Alzheimer's Association International Conference 2015 in Washington D.C., MetLife Foundation presented its annual MetLife Foundation Awards for Medical Research. These awards were presented to Randall Bateman, M.D., and Christian Haass, Ph.D., for their contributions in advancing Alzheimer's disease research.

21 Jul 2015

Children recover well from acute central nervous system demyelination

Most children can expect a good and quick physical recovery following acute central nervous system demyelination, study findings suggest.

20 Jul 2015

WSU's Li Yao explores use of electrical signal for treating spinal cord injuries

Wichita State University's Li Yao is taking a special approach to the study of spinal cord injuries through research that uses an electrical signal to repair tissue damage.

17 Jul 2015

Gene therapy used for sight restoration also strengthens visual pathways in the brain

Since 2007, clinical trials using gene therapy have resulted in often-dramatic sight restoration for dozens of children and adults who were otherwise doomed to blindness. Now, researchers from the Perelman School of Medicine at the University of Pennsylvania and The Children's Hospital of Philadelphia, have found evidence that this sight restoration leads to strengthening of visual pathways in the brain, published this week in Science Translational Medicine.

16 Jul 2015

Discovery brings hope for people suffering from Parkinson's disease

Scientists from Singapore's Nanyang Technological University and McLean Hospital and Harvard Medical School in the United States have found that existing anti-malaria drugs could be a potential treatment for Parkinson's disease.

16 Jul 2015

Research could lead to new approaches to treating spinal cord and brain injuries

Many an injury will heal, but the damaged spinal cord is notoriously recalcitrant. There's new hope on the horizon, though. A team of researchers led by the University of South Carolina's Jeff Twiss just reported an innate repair mechanism in central nervous system axons that might be harnessed to regenerate nerves after brain or spinal cord injuries.

16 Jul 2015

Ferrer begins Lorediplon phase IIa trial in patients with insomnia disorder

Ferrer, a privately-held Spanish pharmaceutical company, today announces the first patient has been recruited into a phase IIa clinical trial to test the efficacy, safety and tolerability profile of Lorediplon in adult patients with insomnia disorder. The study is scheduled to be completed by Q4, 2016.

14 Jul 2015

Central Nervous System News and Research

Obstructive hydrocephalus produces significant decrease in brain neurogenesis

MGH papers reveal the way anesthetics affect brains of older patients and children

Amyloid-beta kinetics reveal link between aging and AD risk

New study launched to find impact of vasculitis on employment, income

Structural brain changes found in chemoradiation-treated glioblastoma patients

First drug produced by 3D printing is approved by FDA

New MS therapies associated with risks and side effects, require active management strategy

Natural protein fragment produced in the brain can inhibit enzyme implicated in Alzheimer's disease

New analysis examines pharmacy expenditures for publicly insured children with serious chronic illness

TSRI scientists awarded grant to explore therapeutic potential of protein receptors in Parkinson's disease, other disorders

Multiple sclerosis relapse management: an interview with Gina Remington

Lupin signs strategic asset purchase agreement with Temmler

Body fat can send stress signals, say University of Florida Health researchers

MetLife Foundation Awards for Medical Research presented at AAIC 2015

Children recover well from acute central nervous system demyelination

WSU's Li Yao explores use of electrical signal for treating spinal cord injuries

Gene therapy used for sight restoration also strengthens visual pathways in the brain

Discovery brings hope for people suffering from Parkinson's disease

Research could lead to new approaches to treating spinal cord and brain injuries

Ferrer begins Lorediplon phase IIa trial in patients with insomnia disorder

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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