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Genomic sequencing reveals the course of COVID-19 in Africa

A new study explores the contribution of genomic sequencing to the scientific understanding of COVID-19, and on the introduction of global public health measures via the ability to pick up new variants early enough.

16 Sep 2022

Study shows differences in treatment outcomes for Black vs. white women with hormone receptor-positive breast cancer

A study led by City of Hope, one of the largest cancer research and treatment organizations in the United States, found that Black women with Stage 1 or 2 breast cancer were almost three times more likely than white women to have tumor shrinkage from hormone therapy delivered prior to surgery, yet Black women were more likely than their white counterparts to have worse outcomes when this type of endocrine therapy before surgery was used at a later stage of disease.

16 Sep 2022

Higher levels of microbiota engraftment linked to greater chances of transplantation success

From incurable intestinal infections to metabolic syndrome, from melanoma, to chronic inflammatory bowel disease, such as irritable bowel syndrome, to Tourette's syndrome: many diseases can potentially be cured by Fecal Microbiota Transplantation (FMT), and researchers from the Catholic University, Rome and the University of Trento have shown that the greater the level of engraftment of the transplanted microorganisms, the greater the chances of success of the therapy.

15 Sep 2022

NIH researchers identify specific network of proteins critical to restore hearing in zebrafish

National Institutes of Health researchers have discovered a specific network of proteins that is necessary to restore hearing in zebrafish through cell regeneration.

14 Sep 2022

CDC Health Alert Network provides recommendations to manage the recent increase in severe respiratory illness among children

The US CDC’s HAN has provided certain recommendations to inform healthcare providers, infection control professionals, clinical laboratories, and public health departments about the recent increase in pediatric cases of severe respiratory illness in several regions of the USA.

14 Sep 2022

Study highlights role of tumor-infiltrating B cells, plasma cells in cancer development and treatment outcomes

Through extensive single-cell analysis, researchers at The University of Texas MD Anderson Cancer Center have created a spatial map of tumor-infiltrating B cells and plasma cells in early-stage lung cancers, highlighting previously unappreciated roles these immune cells play in tumor development and treatment outcomes.

13 Sep 2022

Researchers join forces to 'map' specific variations in more than 25 key cardiac disease genes

One in 100 people have genetic variations that can cause potentially life-threatening heart conditions, including high cholesterol (lipid disorders), heart muscle disease (cardiomyopathies), and abnormal heart rhythms (arrhythmias).

13 Sep 2022

First report of a SARS-CoV-2 variant with an ORF7a deletion that dominated an outbreak

In a recent study posted to the medRxiv* preprint server, researchers in Australia determined whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta-ORF7aΔ17del [open reading frame 7a protein with 17-nucleotide (nt) frameshift-inducing deletion] variant has a fitness advantage over the Delta variant lacking the ORF7aΔ17del deletion (Delta-ORF7aintact) and/or the SARS-CoV-2 lineage (A.2.2).

12 Sep 2022

Self-replicating intradermal RNA vaccine against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers assessed the efficiency of a controllable self-replicating ribonucleic acid (c-srRNA) vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

12 Sep 2022

Vaccinia virus-based vaccines mount a robust immune response against the monkeypox virus

New research has suggested that recommended vaccinia virus (VACV)-based vaccines will mount a robust immune response against the monkeypox virus observed in the current outbreak (MPXV-2022).

12 Sep 2022

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

A team of researchers from the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) has designed in silico "molecular probes" able to track the progress of a protein that misbehaves in different neurodegenerative diseases, such as Amyotrophic Lateral Sclerosis (ALS) and Fronto-Temporal Dementia (FTD).

9 Sep 2022

Scientists reverse the effects of lysosomal storage disorders in patient cells and mice

Scientists at the Icahn School of Medicine at Mount Sinai in New York, the National Center for Advancing Translational Sciences (NCATS), and elsewhere have reversed the effects of several life-threatening inherited neurodegenerative diseases called lysosomal storage disorders (LSDs) in patient cells and mice.

9 Sep 2022

NIH funds $3.35 million to enhance diversity in genomics training

The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, will fund $3.35 million over five years to launch the Genome Research Experiences to Attract Talented Undergraduates into the Genomics Field to Enhance Diversity (GREAT) program.

9 Sep 2022

Individual COVID-19 infections include multiple variants of the SARS-CoV-2 virus, research shows

Researchers at Case Western Reserve University found wide genetic variation in SARS-CoV-2 viruses among 360 patients whose viral infections were genetically sequenced, showing that all individual infections include multiple variants of the virus.

9 Sep 2022

New data analysis approach could help uncover the genetic basis of many diseases

In the era of Big Data, obtaining a huge amount of information is the easy part; knowing what to do with it is another story entirely.

9 Sep 2022

A single genomic change may have given modern humans an advantage over Neanderthals

A single amino acid change in the transketolase-like 1 (TKTL1) protein may have given modern humans an advantage over more ancient contemporaries like Neanderthals by enabling increased neocortical neurogenesis, researchers report.

9 Sep 2022

Can preclinical COVID-19 models help unlock mystery of long-COVID?

In a recently published article in the journal PLOS PATHOGENS, scientists have summarized acute and prolonged clinical manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The review also provides an overview of the potency and utility of preclinical animal models to understand the mechanistic details of acute and long coronavirus disease 2019 (COVID-19).

8 Sep 2022

Comprehensive genetic architecture atlas compiled for mutant RAS genes in cancers

Researchers at the Johns Hopkins Kimmel Cancer Center, three other cancer centers and the Johns Hopkins Bloomberg School of Public Health compiled a comprehensive genetic architecture atlas for mutant RAS genes in human cancers.

8 Sep 2022

How can Legionella pneumophila transmit through the hot water plumbing of residences and office buildings?

Researchers investigate the transmission of the causative agent of legionellosis, Legionella pneumophila, through hot water plumbing systems in commercial and residential buildings.

8 Sep 2022

MD Anderson and Virogin Biotech partner to accelerate the development of investigational treatments for advanced cancers

The University of Texas MD Anderson Cancer Center and Virogin Biotech today announced a strategic collaboration to accelerate the development of investigational treatments, including oncolytic viruses and immunotherapies, for patients with advanced cancers.

7 Sep 2022

Genomic News and Research

Genomic sequencing reveals the course of COVID-19 in Africa

Study shows differences in treatment outcomes for Black vs. white women with hormone receptor-positive breast cancer

Higher levels of microbiota engraftment linked to greater chances of transplantation success

NIH researchers identify specific network of proteins critical to restore hearing in zebrafish

CDC Health Alert Network provides recommendations to manage the recent increase in severe respiratory illness among children

Study highlights role of tumor-infiltrating B cells, plasma cells in cancer development and treatment outcomes

Researchers join forces to 'map' specific variations in more than 25 key cardiac disease genes

First report of a SARS-CoV-2 variant with an ORF7a deletion that dominated an outbreak

Self-replicating intradermal RNA vaccine against SARS-CoV-2

Vaccinia virus-based vaccines mount a robust immune response against the monkeypox virus

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

Scientists reverse the effects of lysosomal storage disorders in patient cells and mice

NIH funds $3.35 million to enhance diversity in genomics training

Individual COVID-19 infections include multiple variants of the SARS-CoV-2 virus, research shows

New data analysis approach could help uncover the genetic basis of many diseases

A single genomic change may have given modern humans an advantage over Neanderthals

Can preclinical COVID-19 models help unlock mystery of long-COVID?

Comprehensive genetic architecture atlas compiled for mutant RAS genes in cancers

How can Legionella pneumophila transmit through the hot water plumbing of residences and office buildings?

MD Anderson and Virogin Biotech partner to accelerate the development of investigational treatments for advanced cancers

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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