Immune System News and Research

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Long term antiretroviral therapy may restore CD4 cell counts in HIV positive patients

HIV positive patients who take combination antiretroviral therapy (cART) to combat HIV infection could see the numbers of CD4 cells in their immune system rise to concentrations found in HIV negative individuals, if they remain on the therapy for long enough and their HIV viral load load is suppressed to below 50 copies per ml.

20 Jul 2007

Three gene variants discovered that help fight HIV

An international team of researchers has identified three gene variants in the DNA of 486 people infected with HIV that appear to have helped some of the patients fight off the virus and delay the onset of full-blown AIDS.

20 Jul 2007

Clearer picture of host responses to HIV virus

The first genome-wide association study of an infectious disease, conducted by an international group of researchers through the Center for HIV/AIDS Vaccine Immunology (CHAVI), has yielded a new understanding of why some people can suppress virus levels following HIV infection.

20 Jul 2007

Clue to preventing Alzheimer's found in Vindaloo

A new study by researchers in the United States has found during laboratory tests that tumeric, a spice used in curries may offer protection against Alzheimer's disease.

19 Jul 2007

Obesity a risk factor for multiple myeloma

An obese person is more likely than a lean person to develop multiple myeloma, according to researchers from Brigham and Women’s Hospital, Harvard Medical School, and Harvard School of Public Health.

19 Jul 2007

Affiris alzheimer's vaccine in clinical trial

The Alzheimer's vaccine known as Affitope AD01 from Affiris has now entered the clinical phase of its development. All relevant regulatory and statutory approvals have been secured and this innovative treatment is now being tested on humans for the first time.

19 Jul 2007

Protecting HIV patients from Hep B

Since the transmission of HIV and Hepatitis B virus (HBV) are so similar, individuals infected with one of these viruses are at a significantly increased risk for contracting the other.

19 Jul 2007

GSK's Cervarix receives positive opinion in Europe

GlaxoSmithKline has announced that its cervical cancer candidate vaccine received a positive opinion from the European Committee for Human Medicinal Products (CHMP) for the prevention of precancerous lesions (high grade cervical intraepithelial neoplasia - CIN grades 2 and 3) and cervical cancer causally related to human papillomavirus types 16 and 18.

19 Jul 2007

C3 gene variant increases risk of blindness

Researchers have found a gene variant that can more than double the risk of developing the degenerative eye disease, age-related macular degeneration.

19 Jul 2007

Discovery of gene variant that increases risk for Crohn's disease

Pediatrics researchers have identified a gene variant that raises a child's risk of Crohn's disease, a chronic and painful condition attributed to inflammation of the gastrointestinal tract.

19 Jul 2007

Protein kinase G holds promise for cancer treatment

An enzyme that cancer cells eliminate, apparently so they can keep proliferating, may hold clues to more targeted, effective cancer treatment, scientists say.

19 Jul 2007

Orchestra Therapeutics discontinues HIV vaccine program

Orchestra Therapeutics, Inc. has announced the discontinuation of its HIV Vaccine Development Program.

18 Jul 2007

Test of universal influenza vaccine

A universal influenza vaccine that has been pioneered by researchers from VIB and Ghent University is being tested for the first time on humans by the British-American biotech company Acambis.

18 Jul 2007

Obesity and asthma often go together

Scientists in Britain say they have discovered a link between obesity and asthma and they believe the connection may explain why overweight people are up to twice as likely to develop the respiratory condition.

17 Jul 2007

Curry chemical bisdemethoxycurcumin may clear amyloid beta plaques

FINDINGS: Researchers isolated bisdemethoxycurcumin, the active ingredient of curcuminoids – a natural substance found in turmeric root – that may help boost the immune system in clearing amyloid beta, a peptide that forms the plaques found in Alzheimer's disease.

17 Jul 2007

Biota and MedImmune announce clinical trial for respiratory syncytial virus antiviral drug

Biota Holdings Limited and MedImmune Inc. today announced the start of a Phase Ia clinical trial for their respiratory syncytial virus (RSV) antiviral drug, BTA9881, with the goal of providing a treatment for RSV-infected infants and adults.

17 Jul 2007

Researchers identify new combination therapy that promotes cancer cell death

Researchers at the University of Pennsylvania School of Medicine identified a combination therapy as a way to sensitize resistant human cancer cells to a treatment currently being tested in clinical trials They propose that the therapy may help to selectively eliminate cancer cells while leaving healthy cells intact, providing a cancer treatment with fewer side effects.

17 Jul 2007

Latest in HIV/TB research

With HIV infection driving a deadly resurgence of tuberculosis (TB), a new publication provides up-to-date recommendations for clinicians facing the many challenges of treating patients with both of these two complex diseases.

17 Jul 2007

Myeloid-derived suppressor cells suppress anti-tumor response to cancer

Scientists at Johns Hopkins and elsewhere say they have mapped out an escape route that cancers use to evade the body's immune system, allowing the disease to spread unchecked.

17 Jul 2007

Diabetics experience more complications during hospitalization for trauma

Individuals with diabetes appear to spend more days in the intensive care unit, use more ventilator support and have more complications during hospitalization for trauma than non-diabetics, according to a report in the July issue of Archives of Surgery.

17 Jul 2007