Central Nervous System News and Research

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International consensus panel reviews new diagnostic criteria for neuromyelitis optica spectrum disorder

New diagnostic criteria were introduced this week for neuromyelitis optica, now called neuromyelitis optica spectrum disorder, which is an inflammatory disease of the central nervous system that is sometimes mistaken for multiple sclerosis.

9 Jul 2015

New NEI study shows that microglia can accelerate damage wrought by blinding eye disorders

Spider-like cells inside the brain, spinal cord and eye hunt for invaders, capturing and then devouring them. These cells, called microglia, often play a beneficial role by helping to clear trash and protect the central nervous system against infection. But a new study by researchers at the National Eye Institute (NEI) shows that they also accelerate damage wrought by blinding eye disorders, such as retinitis pigmentosa.

2 Jul 2015

Wayne State University awarded grant to explore new MS pathology model

The National Multiple Sclerosis Society has provided a grant to a Wayne State University School of Medicine professor to explore a new model of MS pathology.

2 Jul 2015

Robert G. Miller awarded $1.5 million grant to help fund Neuraltus' Phase 2 clinical study of NP001 for ALS

Neuraltus Pharmaceuticals, Inc., a privately-held biopharmaceutical company focused on the development of groundbreaking drugs to treat neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), announced today that Robert G. Miller, M.D., Director of the Forbes Norris MDA/ALS Research Center at Sutter Health's California Pacific Medical Center in San Francisco, has been awarded a grant from The ALS Association for $1.5 million to help fund a Phase 2 clinical study of the company's investigational therapy for ALS, NP001.

1 Jul 2015

Pharma Two B reports positive results from P2B001 Phase IIb study for treatment of early stage PD

Pharma Two B Ltd., a privately held company developing innovative therapeutics based on previously approved drugs, announced today the successful results of the company's Phase IIb pivotal study of P2B001 for the treatment of early stage Parkinson's Disease (PD).

30 Jun 2015

TSRI scientists find five different miRNAs involved in memory formation

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have found that a type of genetic material called “microRNA” plays surprisingly different roles in the formation of memory in animal models. In some cases, these RNAs increase memory, while others decrease it.

30 Jun 2015

Inhibikase Therapeutics receives Phase II SBIR grant to advance novel RAMP medicinal chemistry program

Inhibikase Therapeutics, Inc. announces the receipt of a Phase II SBIR grant in the amount of $1.54 million dollars from the U.S. National Institutes of Health to advance its novel Re-engineering with Metabolism Preserved (RAMP) medicinal chemistry program.

29 Jun 2015

Spinifex Pharmaceuticals enters into agreement to be acquired by Novartis

Spinifex Pharmaceuticals, Inc., a company focused on the development of new drugs for the treatment of chronic pain, today announces that it has agreed to the sale of Spinifex to Novartis International AG, for an upfront cash consideration of US$200 million plus undisclosed clinical development and regulatory milestone payments.

29 Jun 2015

Neuralstem's HK532-IGF-1 neural stem cells therapy for Alzheimer's disease presented at ISSCR Annual Meeting

Neuralstem, Inc., a biopharmaceutical company using neural stem cell technology to develop small molecule and cell therapy treatments for central nervous system diseases, announced that the poster "Human Neural Stem Cells Expressing IGF-1: A Novel Cellular Therapy for Alzheimer's Disease" was presented yesterday at the International Society for Stem Cell Research (ISSCR) Annual Meeting in Stockholm, Sweden.

27 Jun 2015

Hartmuth Kolb named recipient of 2015 Alzheimer Award

The Journal of Alzheimer's Disease is proud to announce that Hartmuth Kolb, PhD, Head of Neuroscience Biomarkers, Johnson & Johnson, San Diego, CA, has been chosen as the recipient of the 2015 Alzheimer Award presented by the Journal of Alzheimer's Disease in recognition of his outstanding work on the importance and imaging of neurofibrillary tangles (NFTs) and Alzheimer's disease (AD).

26 Jun 2015

Innovative gene transfer-based treatment for kids with giant axonal neuropathy

University of North Carolina School of Medicine researchers have developed an innovative, experimental gene transfer-based treatment for children with giant axonal neuropathy (GAN).

26 Jun 2015

Cytokine levels may help distinguish patients with suicidality

One American dies from suicide every 12.8 minutes, making suicide the tenth leading cause of death in the United States according to the American Foundation for Suicide Prevention.

25 Jun 2015

Researchers develop new implantable drug-delivery system using nanowire

A team of researchers has created a new implantable drug-delivery system using nanowires that can be wirelessly controlled.

24 Jun 2015

Iowa's advanced driving simulator to help assess newly developed artificial lens for cataract patients

A miniature version of the University of Iowa's advanced driving simulator will participate in a clinical trial later this year to assess a patient's driving ability after cataract surgery.

17 Jun 2015

Researchers find lymphatic vessels in the central nervous system

In a study published in The Journal of Experimental Medicine, researchers working at the Wihuri Research Institute and the University of Helsinki report a surprising finding that challenges current anatomy and histology textbook knowledge: Lymphatic vessels are found in the central nervous system where they were not known to exist.

16 Jun 2015

LMU clinicians reveal mechanism involved in determining lifetime of antibody-producing cells

Clinicians at Ludwig-Maximilians-Universitaet in Munich have elucidated a mechanism involved in determining the lifespan of antibody-producing cells, and identified a promising new biomarker for monitoring autoimmune diseases like multiple sclerosis and lupus erythematosus.

15 Jun 2015

Scientists identify gene mutation linked to anaplastic oligodendroglioma

Scientists have identified a gene mutation linked to the development of an aggressive form of brain cancer. Researchers found that errors in a gene known as TCF12 - which plays a key role in the formation of the embryonic brain are associated with more aggressive forms of a disease called anaplastic oligodendroglioma.

12 Jun 2015

α-synuclein conformation may underlie neurodegenerative variability

Varying structural conformations of α-synuclein may explain how one protein can give rise to distinct forms of neurodegeneration, say researchers.

12 Jun 2015

Promising results for multi-source DBS in Parkinson’s disease

Deep-brain stimulation targeting the subthalamic nucleus with a multiple-source constant-current device effectively suppresses motor symptoms in patients with advanced Parkinson’s disease, report researchers.

12 Jun 2015

Scientists find new way of classifying brain cancers

Not all brain cancers are the same but together they represent a deadly disease that has been difficult to identify and treat. Scientists at multiple institutions have found a new way of classifying brain cancers that could very well change how the illness is diagnosed and treated.

11 Jun 2015

Central Nervous System News and Research

International consensus panel reviews new diagnostic criteria for neuromyelitis optica spectrum disorder

New NEI study shows that microglia can accelerate damage wrought by blinding eye disorders

Wayne State University awarded grant to explore new MS pathology model

Robert G. Miller awarded $1.5 million grant to help fund Neuraltus' Phase 2 clinical study of NP001 for ALS

Pharma Two B reports positive results from P2B001 Phase IIb study for treatment of early stage PD

TSRI scientists find five different miRNAs involved in memory formation

Inhibikase Therapeutics receives Phase II SBIR grant to advance novel RAMP medicinal chemistry program

Spinifex Pharmaceuticals enters into agreement to be acquired by Novartis

Neuralstem's HK532-IGF-1 neural stem cells therapy for Alzheimer's disease presented at ISSCR Annual Meeting

Hartmuth Kolb named recipient of 2015 Alzheimer Award

Innovative gene transfer-based treatment for kids with giant axonal neuropathy

Cytokine levels may help distinguish patients with suicidality

Researchers develop new implantable drug-delivery system using nanowire

Iowa's advanced driving simulator to help assess newly developed artificial lens for cataract patients

Researchers find lymphatic vessels in the central nervous system

LMU clinicians reveal mechanism involved in determining lifetime of antibody-producing cells

Scientists identify gene mutation linked to anaplastic oligodendroglioma

α-synuclein conformation may underlie neurodegenerative variability

Promising results for multi-source DBS in Parkinson’s disease

Scientists find new way of classifying brain cancers

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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