Clinical Trial News and Research

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Study highlights global fertility decline and its implications for the future

The world is approaching a low-fertility future. Although by 2100 more than 97% of countries and territories will have fertility rates below what is necessary to sustain population size over time, comparatively high fertility rates in numerous low-income countries, predominantly in western and eastern sub-Saharan Africa, will continue to drive population increases in these locations throughout the century.

21 Mar 2024

Low-dose boost of radiotherapy keeps young breast cancer patients recurrence-free

The vast majority of young patients given a low-dose boost of radiotherapy to the site where their breast cancer was removed in addition to whole breast radiotherapy, remained free of local recurrence after ten years, according to results of the 'Young boost trial' presented at the 14th European Breast Cancer Conference.

21 Mar 2024

Researchers develop AI tool to predict side effects of treatment in breast cancer patients

A team of international researchers have developed an artificial intelligence (AI) tool that can predict which breast cancer patients may be at risk of side effects after surgery and radiotherapy.

21 Mar 2024

Advancing precision personalized medicine for gastric cancer with 3D bioprinting

Gastric cancer ranks among the most widespread diseases in Asian populations, with South Koreans experiencing the third-highest incidence globally in 2020, as reported by the International Agency for Research on Cancer.

21 Mar 2024

Exploring the role of iodine in obesity, diabetes, and other metabolic conditions

The metabolic implications of iodine consumption and elucidated the underlying mechanisms.

21 Mar 2024

Investigational gene therapy shows promise for rare childhood neurodegenerative disease

An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy (GAN), was well tolerated and showed signs of therapeutic benefit in a clinical trial led by the National Institutes of Health.

20 Mar 2024

New treatment approach improves recurrence-free survival in early breast cancer patients

A new treatment approach that combines a targeted therapy drug with hormone therapy significantly increased the amount of time a person with stage 2 or 3 HR-positive, HER2-negative early breast cancer lives without the cancer returning, according to a new study co-led by UCLA Health Jonsson Comprehensive Cancer Center investigators.

20 Mar 2024

Skin biopsy test shows promise in diagnosing Parkinson's disease and synucleinopathies

In a paper published in the Journal of the American Medical Association (JAMA), neurologists at Beth Israel Deaconess Medical Center (BIDMC) showed that a simple skin biopsy test detects an abnormal form of alpha-synuclein, the pathological hallmark of Parkinson's disease and the subgroup of neurodegenerative disorders known as synucleinopathies, at high positivity rates.

20 Mar 2024

AI-based mobile app can diagnose melanoma with very high precision

A mobile app that uses artificial intelligence, AI, to analyze images of suspected skin lesions can diagnose melanoma with very high precision.

20 Mar 2024

Genetic test can identify how patients with triple negative early-stage breast cancer will respond to immunotherapy

Researchers have developed a genetic test that can identify how patients with triple negative early-stage breast cancer will respond to immunotherapy drugs.

20 Mar 2024

Pembrolizumab enhances breast cancer treatment regardless of age or menopausal status

New data from the KEYNOTE-756 phase 3 clinical trial show that adding the immunotherapy drug, pembrolizumab, to chemotherapy before and after surgery for breast cancer leads to better outcomes for patients regardless of their age or menopausal status.

20 Mar 2024

SolasCure Awarded £405K Innovate UK Biomedical Catalyst Grant to Advance Chronic Wound Care

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From SolasCure 20 Mar 2024

Tracking circulating tumor DNA could indicate gastroesophageal cancer treatment response

Monitoring levels of DNA shed by tumors and circulating in the bloodstream could help doctors accurately assess how gastroesophageal cancers are responding to treatment, and potentially predict future prognosis, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

19 Mar 2024

Web-based decision aid helps pregnant women to make informed decisions about sterilization

Researchers at the University of Pittsburgh have developed a simple, web-based decision aid called My Decision/Mi Decisión that helps empower pregnant individuals who are considering tubal sterilization to make informed decisions about their reproductive health, according to a new study published today in JAMA Network Open.

19 Mar 2024

Discovery could revolutionize stem cell-based brain repair therapy for Parkinson's disease

Neuroscientists at University of Galway have made an exciting discovery that could revolutionize stem cell-based brain repair therapy for Parkinson's disease.

19 Mar 2024

Ownership-based text messages boost COVID booster uptake

New research published in Nature Human Behavior suggests that text nudges encouraging people to get the COVID-19 vaccine, which had proven effective in prior real-world field tests, are also effective at prompting people to get a booster.

18 Mar 2024

Peer coaching effective in controlling high blood pressure in young Black patients

For younger Black patients living in rural parts of the Southeastern United States, peer coaching is more effective than traditional clinical care in controlling high blood pressure, according to a new study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian.

18 Mar 2024

Apple cider vinegar shows promise for weight management in overweight and obese individuals

Small daily quantities of apple cider vinegar for 12 weeks aid weight management in people who are overweight or obese, suggest the results of a small comparative clinical trial, published in the open access journal BMJ Nutrition, Prevention & Health.

18 Mar 2024

Dosing software accelerates antibiotic effects in ICU patients treated for sepsis

University of Queensland researchers have used dosing software to accelerate the effects of antibiotics in patients being treated for sepsis in Intensive Care Units.

18 Mar 2024

Clinical trial aims to provide a surgical solution for patients with 'inoperable' pancreatic tumors

A clinical trial from Keck Medicine of USC aims to provide a surgical solution for patients with a form of advanced pancreatic cancer previously considered inoperable.

18 Mar 2024

Clinical Trial News and Research

Study highlights global fertility decline and its implications for the future

Low-dose boost of radiotherapy keeps young breast cancer patients recurrence-free

Researchers develop AI tool to predict side effects of treatment in breast cancer patients

Advancing precision personalized medicine for gastric cancer with 3D bioprinting

Exploring the role of iodine in obesity, diabetes, and other metabolic conditions

Investigational gene therapy shows promise for rare childhood neurodegenerative disease

New treatment approach improves recurrence-free survival in early breast cancer patients

Skin biopsy test shows promise in diagnosing Parkinson's disease and synucleinopathies

AI-based mobile app can diagnose melanoma with very high precision

Genetic test can identify how patients with triple negative early-stage breast cancer will respond to immunotherapy

Pembrolizumab enhances breast cancer treatment regardless of age or menopausal status

SolasCure Awarded £405K Innovate UK Biomedical Catalyst Grant to Advance Chronic Wound Care

Tracking circulating tumor DNA could indicate gastroesophageal cancer treatment response

Web-based decision aid helps pregnant women to make informed decisions about sterilization

Discovery could revolutionize stem cell-based brain repair therapy for Parkinson's disease

Ownership-based text messages boost COVID booster uptake

Peer coaching effective in controlling high blood pressure in young Black patients

Apple cider vinegar shows promise for weight management in overweight and obese individuals

Dosing software accelerates antibiotic effects in ICU patients treated for sepsis

Clinical trial aims to provide a surgical solution for patients with 'inoperable' pancreatic tumors

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