Immune System News and Research

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Discovery of mobile regulatory T cells could revolutionize disease treatment

Scientists at the University of Cambridge have discovered that a type of white blood cell - called a regulatory T cell - exists as a single large population of cells that constantly move throughout the body looking for, and repairing, damaged tissue.

18 Jun 2024

Personalized medicine approaches for sepsis based on immune response profiling

Sepsis patients could be treated based on their immune system's response to infection, not their symptoms.

18 Jun 2024

Existing cancer drug shows promise in blocking alpha-synuclein spread in Parkinson's mice

In studies with genetically engineered mice, Johns Hopkins Medicine researchers say they have identified a potentially new biological target involving Aplp1, a cell surface protein that drives the spread of Parkinson's disease-causing alpha-synuclein.

18 Jun 2024

Innovative bread formulation shows promise in preventing asthma

Brazilian researchers have developed functional bread with the potential to prevent asthma, a respiratory disorder responsible for some 350,000 hospitalizations per year in the SUS (Sistema Único de Saúde), the nation's public healthcare network.

17 Jun 2024

Global Omega-3 Index map update reveals persistent data gaps and low levels

A study in Progress in Lipid Research updated the global Omega-3 Index map, revealing improvements in some regions but highlighting significant data gaps and low levels in many countries, stressing the need for global intervention.

16 Jun 2024

St. Jude researchers uncover NLRC5's role in immune response and cell death

The innate immune system is responsible for protecting the human body from threats that could cause disease or infection.

14 Jun 2024

TIMP-1 protein found to boost immune system's fight against cancer

Researchers at the University of Turku in Finland have found a new function for an existing protein.

14 Jun 2024

Case study sheds light on CAR-T therapy-related secondary cancers

A new detailed analysis of a patient's second cancer after receiving CAR-T therapy for the initial cancer provides rare but important insights intended to offer helpful guidance for oncologists and pathologists about the clinical presentation and pathologic features involved in a CAR-T related second cancer.

13 Jun 2024

Pre-surgery GLP-1 agonists reduce post-operative risks in extreme obesity

A combination of GLP-1 agonists taken before metabolic and bariatric surgery may help patients with extreme obesity lower the risk of post-operative complications, according to a new study presented today at the American Society for Metabolic and Bariatric Surgery 2024 Annual Scientific Meeting.

13 Jun 2024

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Scientists at Weill Cornell Medicine discovered a previously unknown link between two key pathways that regulate the immune system in mammals - a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD).

12 Jun 2024

Study identifies drug target to prevent autonomic dysfunction after spinal cord injury

In response to stressful or dangerous stimuli, nerve cells in the spinal cord activate involuntary, autonomic reflexes often referred to as "fight or flight" responses.

12 Jun 2024

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

A large study by researchers at Stanford Medicine has found that the risk of secondary blood cancers after CAR-T cell therapy - a cell-based cancer treatment that exploded on the scene in 2017 as a treatment for intractable blood cancers - is low, despite a Food and Drug Administration warning.

12 Jun 2024

Gastric bypass maintains weight loss and diabetes remission over 15 years, study shows

Roux-en-Y gastric bypass, a type of weight-loss surgery, kept type 2 diabetes in remission for up to 15 years and most of the weight off for up to 20 years in one of the largest long-term studies of patients undergoing the procedure.

12 Jun 2024

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

Tokyo Medical and Dental University (TMDU) researchers harness long-read RNA sequencing to decode genetic intricacies and disease links.

12 Jun 2024

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

Engineers at the University of California San Diego have developed microscopic robots, known as microrobots, capable of swimming through the lungs to deliver cancer-fighting medication directly to metastatic tumors.

12 Jun 2024

Macrophages play an unexpected role in the complicated obesity-cancer connection

Immune system cells called macrophages play an unexpected role in the complicated connection between obesity and cancer, a Vanderbilt University Medical Center-led research team has discovered.

12 Jun 2024

Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

Attenuated virus helps eliminate cancer in mice

Northwestern Medicine scientists have discovered that an attenuated (weakened) virus can help eliminate cancer in mice.

11 Jun 2024

Study highlights metabolic surgery's role in diabetes prevention

Patients with pre-diabetes and severe obesity who had metabolic and bariatric surgery were 20-times less likely to develop full-blown type 2 diabetes over the course of 15 years than patients with the condition who did not have surgery, according to a new study presented today at the American Society for Metabolic and Bariatric Surgery (ASMBS) 2024 Annual Scientific Meeting.

11 Jun 2024

Metabolic surgery proven most effective for sustained weight loss over GLP-1 drugs and lifestyle interventions

Systematic reviews of medical literature between 2020 to 2024 show bariatric surgery, also known as metabolic or weight-loss surgery, produces the greatest and most sustained weight loss compared to GLP-1 receptor agonists and lifestyle interventions.

11 Jun 2024

Immune System News and Research

Discovery of mobile regulatory T cells could revolutionize disease treatment

Personalized medicine approaches for sepsis based on immune response profiling

Existing cancer drug shows promise in blocking alpha-synuclein spread in Parkinson's mice

Innovative bread formulation shows promise in preventing asthma

Global Omega-3 Index map update reveals persistent data gaps and low levels

St. Jude researchers uncover NLRC5's role in immune response and cell death

TIMP-1 protein found to boost immune system's fight against cancer

Case study sheds light on CAR-T therapy-related secondary cancers

Pre-surgery GLP-1 agonists reduce post-operative risks in extreme obesity

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Study identifies drug target to prevent autonomic dysfunction after spinal cord injury

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

Gastric bypass maintains weight loss and diabetes remission over 15 years, study shows

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

Macrophages play an unexpected role in the complicated obesity-cancer connection

Enhancing CAR-T cell therapy with biodegradable scaffolds

Attenuated virus helps eliminate cancer in mice

Study highlights metabolic surgery's role in diabetes prevention

Metabolic surgery proven most effective for sustained weight loss over GLP-1 drugs and lifestyle interventions

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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