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UIC researchers describe role of unique pressure-sensing protein in lung edema

Researchers at the University of Illinois at Chicago describe for the first time the role of a unique, pressure-sensing protein in the development of lung edema -- a condition in which chronic high vascular pressure in the lungs causes fluid from the bloodstream to enter the air spaces of the lungs.

11 Jun 2019

Researchers succeed in conquering chronic infection with hepatitis B virus

Researchers at Helmholtz Zentrum München and the Technical University of Munich, working in collaboration with researchers at the University Medical Center Hamburg-Eppendorf and the University Hospital Heidelberg, have for the first time succeeded in conquering a chronic infection with the hepatitis B virus in a mouse model.

11 Jun 2019

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

Patients with chronic myeloid leukemia can be treated with tyrosine kinase inhibitors. While these effective drugs lead to deep remission and prolonged survival, primitive leukemia stem cells resist elimination during the remission and persist as a major barrier to cure.

11 Jun 2019

Bacteriophage can have a profound impact on the dynamics of gut microbiome, study finds

The gut microbiome is a complex, interconnected ecosystem of species. And, like any ecosystem, some organisms are predators and some are prey.

7 Jun 2019

CAPON protein may facilitate link between two most well-known Alzheimer's culprits

A new protein involved in Alzheimer's disease has been identified by researchers at the RIKEN Center for Brain Science.

7 Jun 2019

Rettsyndrome.org funds research that will benefit boys and girls with MECP2-related disorders

Rettsyndrome.org announced their funding of two new research projects today. Jeannie T. Lee, MD, Ph.D. of Massachusetts General Hospital is awarded a two-year ANGEL Grant for $600,000 to focus on reactivating the silent X chromosome for Rett syndrome and Davut Pehlivan, MDof Baylor College of Medicine is awarded a two-year Mentored Clinical Fellowship for $250,000 to study MECP2 Duplication syndrome.

6 Jun 2019

Study offers hope to slow down or prevent progression of Parkinson’s

Results from a study published today looking at a molecule targeting clumps of alpha-synuclein, a key protein linked to Parkinson’s, offers hope that it may be possible to slow down or prevent the progression of the condition in humans.

6 Jun 2019

Texas Biomed awarded $2 million DOD grant to study promising Zika vaccine

The emerging Zika virus is a particular threat to pregnant women. The disease can be transmitted by the bite of an infected mosquito and is associated with devastating birth defects, like microcephaly. No approved vaccine against the virus exists.

3 Jun 2019

Gut bacteria linked to metabolic changes and autism in new study

Researchers have made an important discovery that may explain how gut bacteria could contribute to autism-like behaviors.

31 May 2019

UAB study reveals how enzyme lipoxygenase drives heart failure after heart attacks

Heart failure after a heart attack is a global epidemic leading to chronic heart failure pathology. About 6 million people in the United States and 23 million worldwide suffer from this end-stage disease that involves dysfunction of the heart, a change that clinicians call cardiac remodeling.

31 May 2019

Concussion symptoms can be reversed by magnetic stimulation

Concussion symptoms--such as loss of balance, hazy comprehension, sleep disturbance and ability to walk straight--can be reversed by a new type of magnetic stimulation, research at the University of Saskatchewan shows.

30 May 2019

Dysfunctional neurons repaired in dementia mouse model

Dysfunctional neurons in the hippocampus of adult female mice modeling dementia can be repaired and reconnected to distant parts of the brain, reports a new study published in JNeurosci.

From Society for Neuroscience 28 May 2019

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own genetically modified T cells equipped to mount a potent anti-tumor attack.

28 May 2019

UAB study reveals detrimental role of neutrophils in multiple sclerosis

Multiple sclerosis is an autoimmune disease that damages the insulating sheaths of nerve cells of the central nervous system. People with the disease can lose vision, suffer weak limbs, show degenerative symptoms and exhibit impaired cognition.

26 May 2019

Study demonstrates the concept of systemic gene therapy treatment for gamma-sarcoglycanopathy

Gamma-sarcoglycanopathy is one of the most common limb-girdle myopathies.

25 May 2019

Cell scientist receives $1.9 million NIH grant to study muscle regeneration

As people age, their muscle regeneration capacity declines in part because they can no longer make enough muscle stem cells to replace damaged tissue.

24 May 2019

Researchers map bone-marrow microenvironment to shed new light on leukemia

Stem cells are surrounded and protected by the stem-cell niche - the microenvironment - of the tissue in which they are found.

24 May 2019

EU-funded project works to better understand human and parasite interactions

Whipworms are parasitic roundworms that live preferentially in the human cecum, the blind pouch at the beginning of the large intestine. They tunnel through epithelial cells and cause inflammation, potentially resulting in trichuriasis, an infection similar to colitis.

23 May 2019

Study reveals hidden changes that happen to female heart during perimenopause

It's known the female heart changes after menopause, but a new University of Guelph study is the first to reveal hidden changes that are happening during perimenopause- the stage before menopause sets in.

23 May 2019

Genetic variation in heart valve cells of developing fetus creates mitral valve prolapse

Genetic variation in heart valve cells of the developing fetus create the blueprint for the later development of mitral valve prolapse, according to the cover story of today's Science Translational Medicine.

23 May 2019

Mouse Model News and Research

UIC researchers describe role of unique pressure-sensing protein in lung edema

Researchers succeed in conquering chronic infection with hepatitis B virus

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

Bacteriophage can have a profound impact on the dynamics of gut microbiome, study finds

CAPON protein may facilitate link between two most well-known Alzheimer's culprits

Rettsyndrome.org funds research that will benefit boys and girls with MECP2-related disorders

Study offers hope to slow down or prevent progression of Parkinson’s

Texas Biomed awarded $2 million DOD grant to study promising Zika vaccine

Gut bacteria linked to metabolic changes and autism in new study

UAB study reveals how enzyme lipoxygenase drives heart failure after heart attacks

Concussion symptoms can be reversed by magnetic stimulation

Dysfunctional neurons repaired in dementia mouse model

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

UAB study reveals detrimental role of neutrophils in multiple sclerosis

Study demonstrates the concept of systemic gene therapy treatment for gamma-sarcoglycanopathy

Cell scientist receives $1.9 million NIH grant to study muscle regeneration

Researchers map bone-marrow microenvironment to shed new light on leukemia

EU-funded project works to better understand human and parasite interactions

Study reveals hidden changes that happen to female heart during perimenopause

Genetic variation in heart valve cells of developing fetus creates mitral valve prolapse

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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