Immune System News and Research

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New regulatory mechanism for critical protein signaling domain

The study is being published in Science Express, an advanced online edition of the journal Science, on April 5. It will appear in the print version of Science later this spring.

7 Apr 2007

Researchers show blood-brain barrier damage could affect multiple sclerosis severity

Immunology researchers at the Kimmel Cancer Center at Jefferson studying a multiple sclerosis (MS)-like disease in mice have shown that the amount of "damage" to the central nervous system's protective blood-brain barrier, in essence, opening it, almost always correlates to the severity of the disease.

7 Apr 2007

Method for making new molecules based on flavonoids - implications for cancer therapeutics

You've heard of them -- the good-for-your-health compounds found in plants that we enjoy in red wine, dark chocolate, green tea and citrus fruits.

5 Apr 2007

Severe reduction of Treg cells may be involved in development of pemphigus vulgaris

Several T cell subsets with immunosuppressive functions have been reported to demonstrate their suppressive capabilities to the acquired immune system in animal autoimmune disease models.

5 Apr 2007

FDA issues Salmonella alert for Pet Chews - potential for cross contamination, in people, especially children

The Food and Drug Administration (FDA) today warned consumers not to use American Bullie A.B. Bull Pizzle Puppy Chews and Dog Chews manufactured and distributed by T.W. Enterprises, Ferndale, WA, because they have the potential to be contaminated with Salmonella, which can cause serious infections in dogs and cats, and, if there is cross contamination, in people, especially children, the aged, and people with compromised immune systems.

5 Apr 2007

Hepatitis C virus can block other hepatitis C variants from infecting the same cell

There's infection and then there's superinfection - when a cell already infected by a virus gets a second viral infection. But some viruses don't like to share their cells.

5 Apr 2007

St. Jude Children's Research Hospital designated as Center of Excellence for Influenza Research and Surveillance

St. Jude Children's Research Hospital has been designated one of six Centers of Excellence for Influenza Research and Surveillance funded by the National Institute of Allergy and Infectious Diseases (NIAID), a part of the National Institutes of Health.

4 Apr 2007

CD4 Initiative to develop easy to use device that can measure CD4+ T-lymphocytes in HIV+ patients

Researchers at Rush University Medical Center have been selected to participate in a collaborative initiative to develop a simple, affordable and rapid test to measure the immune systems of people infected with HIV/AIDS in developing countries.

4 Apr 2007

New blood test to rapidly detect levels of radiation exposure

In the event of a nuclear or radiological catastrophe -- such as a nuclear accident or a "dirty bomb" -- thousands of people would be exposed to radiation, with no way of quickly determining how much of the deadly substance has seeped inside their bodies.

4 Apr 2007

FDA approves Twinrix

GlaxoSmithKline has announced that the U.S. Food and Drug Administration (FDA) has approved Twinrix [Hepatitis A Vaccine (Inactivated) and Hepatitis B (Recombinant) Vaccine], for an accelerated dosing schedule that consists of three doses given within three weeks followed by a booster dose at 12 months.

4 Apr 2007

Scientists take a close look at early events in immune response

A Sandia National Laboratories research team led by Anup Singh is taking a new approach to studying how immune cells respond to pathogens in the first few minutes and hours of exposure.

4 Apr 2007

Connection found between allergic diseases and autoimmune diseases

A new study by researchers at Children's Hospital and Regional Medical Center and the University of Washington (UW) identifies a connection between allergic diseases such as atopic dermatitis, also known as eczema, and autoimmune diseases. The study was published in the April 1, 2007 edition of Nature Immunology.

4 Apr 2007

Researchers document rare case of hepatitis B virus transmission

Researchers have documented a case of hepatitis B virus (HBV) transmission between two patients at a dentist's office in the United States.

4 Apr 2007

Targeted therapies improve colon cancer survival rates

People diagnosed with advanced colorectal cancer that has spread to distant organs, such as White House spokesman Tony Snow, are much more likely to survive today than even just a few years ago, due to the recent and continued emergence of improved therapies, say cancer experts.

3 Apr 2007

Rabies vaccine approach against HIV shows promise

Rabies, a relentless, ancient scourge, may hold a key to defeating another implacable foe: HIV. Scientists at Jefferson Medical College in Philadelphia have used a drastically weakened rabies virus to ferry HIV-related proteins into animals, in essence, vaccinating them against an AIDS-like disease.

3 Apr 2007

Children who get frequent infections may have immunodeficiency

Children who get frequent infections, such as ear infections, sinusitis or pneumonia, may have a more severe condition called immunodeficiency, according to the American Academy of Allergy, Asthma & Immunology (AAAAI).

3 Apr 2007

Filtering white cells from donor blood before transfusion is much safer for patients

The practice of removing the white cells from blood is called leukoreduction. But despite the recommendations of two national advisory committees in 10 years that voted in favor of all patients in the United States receiving leukoreduced blood, ("universal leukoreduction"), the practice is still not wholly supported in the medical community, nor recommended by the Food and Drug Administration. Part of the reason is fear of increased cost.

3 Apr 2007

Antisocial behaviour in boys leads to poor health in men

A study of over 500 men born in the early 70s in Dunedin reveals that the costs associated with antisocial behaviour may be much higher than previously thought. The research led by scientists from the MRC Social, Genetic and Developmental Psychiatry Centre based at the Institute of Psychiatry, King's College London is published in Archives of General Psychiatry.

3 Apr 2007

Key protein identified in immune response to malaria and TB

An international team of researchers has identified a key protein involved in the immune system's response to malaria, tuberculosis (TB) and a number of other infectious diseases.

3 Apr 2007

We need to balance out our intake of omega-6 and omega-3 fatty acids

A new study suggests that people whose diets contain dramatically more of one kind of polyunsaturated fatty acid than another may be at greater risk for both clinical depression and certain inflammatory diseases.

3 Apr 2007

Immune System News and Research

New regulatory mechanism for critical protein signaling domain

Researchers show blood-brain barrier damage could affect multiple sclerosis severity

Method for making new molecules based on flavonoids - implications for cancer therapeutics

Severe reduction of Treg cells may be involved in development of pemphigus vulgaris

FDA issues Salmonella alert for Pet Chews - potential for cross contamination, in people, especially children

Hepatitis C virus can block other hepatitis C variants from infecting the same cell

St. Jude Children's Research Hospital designated as Center of Excellence for Influenza Research and Surveillance

CD4 Initiative to develop easy to use device that can measure CD4+ T-lymphocytes in HIV+ patients

New blood test to rapidly detect levels of radiation exposure

FDA approves Twinrix

Scientists take a close look at early events in immune response

Connection found between allergic diseases and autoimmune diseases

Researchers document rare case of hepatitis B virus transmission

Targeted therapies improve colon cancer survival rates

Rabies vaccine approach against HIV shows promise

Children who get frequent infections may have immunodeficiency

Filtering white cells from donor blood before transfusion is much safer for patients

Antisocial behaviour in boys leads to poor health in men

Key protein identified in immune response to malaria and TB

We need to balance out our intake of omega-6 and omega-3 fatty acids

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