Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Which biomarkers can help predict adverse outcomes in COVID-19?

A team of researchers has conducted a systematic review to identify laboratory factors that can predict the risk of severe and critical COVID-19 as well as associated mortality rates. The team – from institutions in India and the USA – recently published their findings in the Journal of Clinical Medicine Research.

24 May 2021

Researchers are developing first prognostic, therapeutic epigenetic biomarker for pancreatic cancer patients

By 2030, pancreatic ductal adenocarcinoma (PDAC), the most lethal form of pancreatic cancer, is projected to become the second leading cause of cancer-related deaths in the United States.

24 May 2021

New global study highlights vast under-treatment of diabetes

Nearly half a billion people on the planet have diabetes, but most of them aren't getting the kind of care that could make their lives healthier, longer and more productive, according to a new global study of data from people with the condition.

22 May 2021

FDA approves Rybrevant for treating subset of non-small cell lung cancer

Today, the U.S. Food and Drug Administration approved Rybrevant (amivantamab-vmjw) as the first treatment for adult patients with non-small cell lung cancer whose tumors have specific types of genetic mutations: epidermal growth factor receptor (EGFR) exon 20 insertion mutations.

21 May 2021

Emotional support animals can provide quantifiable benefits to people with serious mental illness

A team led by a social work researcher at The University of Toledo has published the first empirical evidence that emotional support animals can provide quantifiable benefits to individuals with serious mental illness who are experiencing depression, anxiety and loneliness.

21 May 2021

Phase 3 trial: New biologic therapy improves outcomes in adults, adolescents with severe asthma

Results from the NAVIGATOR study of tezepelumab showed that the new biologic therapy significantly reduced exacerbations requiring hospital stays and emergency department (ED) visits for adults and adolescents with severe, uncontrolled asthma, according to research presented at the ATS 2021 International Conference.

20 May 2021

Tobacco smoke exposure in utero and during early childhood can affect children's lung function

Environmental tobacco smoke exposure in utero and during early childhood - especially secondhand smoke - is associated with decreased childhood lung function, according to research presented at the ATS 2021 International Conference.

20 May 2021

Expert panel provides guidance for optimized design of early drug trials for Alzheimer's, related dementias

An expert panel convened by the Alzheimer's Drug Discovery Foundation (ADDF) and The Association for Frontotemporal Degeneration (AFTD) provides guidance on best practices for the design of early drug trials for Alzheimer's disease, frontotemporal degeneration (FTD), and other neurodegenerative dementias.

19 May 2021

Owlstone Medical Launches Breath Testing for Digestive Health in Collaboration with Functional Gut Diagnostics and Functional Gut Clinic

Owlstone Medical today announced agreements with Functional Gut Clinic ("FGC") and Functional Gut Diagnostics (“FGD”).

From Owlstone Medical Ltd 18 May 2021

Researchers use special "micro-grid" recording device to measure hippocampus activity

Researchers at UC San Francisco have observed a new feature of neural activity in the hippocampus - the brain's memory hub - that may explain how this vital brain region combines a diverse range of inputs into a multi-layered memories that can later be recalled.

17 May 2021

Simple sugar could play a key role in the development of progressive MS

Multiple sclerosis, or MS for short, manifests itself slightly differently in each person - which is why some call it "the disease of a thousand faces."

12 May 2021

LLNL-developed thin-film electrodes generate never-before-seen recordings of brain activity

Thin-film electrodes developed at Lawrence Livermore National Laboratory have been used in human patients at the University of California, San Francisco, generating never-before-seen recordings of brain activity in the hippocampus, a region responsible for memory and other cognitive functions.

12 May 2021

Covid-19 patients show reduced gray matter volume in the brain

Covid-19 patients who receive oxygen therapy or experience fever show reduced gray matter volume in the frontal-temporal network of the brain, according to a new study led by researchers at Georgia State University and the Georgia Institute of Technology.

12 May 2021

3D printing technique extends the possibilities of lateral flow tests

Researchers at KU Leuven (Belgium) have developed a 3D printing technique that extends the possibilities of lateral flow testing.

10 May 2021

Researchers identify first biomarker to predict severity of COVID-19

Severe cases of COVID-19 can now be detected at an early stage. Researchers at the University of Zurich have identified the first biomarker that can reliably predict which patients will develop severe symptoms.

10 May 2021

Vegetarians may have a healthier biomarker profile than meat-eaters, indicates study

Vegetarians appear to have a healthier biomarker profile than meat-eaters, and this applies to adults of any age and weight, and is also unaffected by smoking and alcohol consumption, according to a new study in over 166,000 UK adults, being presented at this week's European Congress on Obesity (ECO), held online this year.

10 May 2021

Study provides new insight on how HER2-low tumors may evolve in breast cancer patients

The finding that breast tumors can evolve to express low HER2 potentially widens the number of patients who can benefit from new investigational agents, typically novel antibody-drug conjugate therapies, that are currently in clinical trials for HER2-low tumors.

8 May 2021

Novel biomarker discovered to identify male COVID-19 patients at greatest risk for ICU admission

Researchers have discovered a novel biomarker to identify male COVID-19 patients most at risk for ICU admission.

7 May 2021

New $10.7 million project aims to study the genetic underpinnings of Alzheimer's disease

Despite decades of research and investment, the genetic underpinnings of Alzheimer's disease are still largely unknown, stymieing drug development and early diagnosis efforts.

5 May 2021

$Mild depression may predict postoperative delirium in older adults undergoing hip fracture repair$

Mild depression may predict postoperative delirium in older adults undergoing hip fracture repair

Screening for even mild depressive symptoms before hip fracture repair may be helpful in predicting which patients are at higher risk of developing delirium after emergency surgery, according to results of a new study by researchers from Johns Hopkins Medicine.

4 May 2021

Biomarker News and Research

Further Reading

Which biomarkers can help predict adverse outcomes in COVID-19?

Researchers are developing first prognostic, therapeutic epigenetic biomarker for pancreatic cancer patients

New global study highlights vast under-treatment of diabetes

FDA approves Rybrevant for treating subset of non-small cell lung cancer

Emotional support animals can provide quantifiable benefits to people with serious mental illness

Phase 3 trial: New biologic therapy improves outcomes in adults, adolescents with severe asthma

Tobacco smoke exposure in utero and during early childhood can affect children's lung function

Expert panel provides guidance for optimized design of early drug trials for Alzheimer's, related dementias

Owlstone Medical Launches Breath Testing for Digestive Health in Collaboration with Functional Gut Diagnostics and Functional Gut Clinic

Researchers use special "micro-grid" recording device to measure hippocampus activity

Simple sugar could play a key role in the development of progressive MS

LLNL-developed thin-film electrodes generate never-before-seen recordings of brain activity

Covid-19 patients show reduced gray matter volume in the brain

3D printing technique extends the possibilities of lateral flow tests

Researchers identify first biomarker to predict severity of COVID-19

Vegetarians may have a healthier biomarker profile than meat-eaters, indicates study

Study provides new insight on how HER2-low tumors may evolve in breast cancer patients

Novel biomarker discovered to identify male COVID-19 patients at greatest risk for ICU admission

New $10.7 million project aims to study the genetic underpinnings of Alzheimer's disease

Mild depression may predict postoperative delirium in older adults undergoing hip fracture repair

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