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Primate brain cell atlas provides molecular and cellular basis for neural circuit research

A team of nearly 100 scientists recently mapped the cell-type taxonomy in the macaque cortex and revealed the relationship between cell-type composition and various primate brain regions by using the self-developed spatial transcriptome sequencing technology Stereo-seq and snRNA-seq technology, which provides a molecular and cellular basis for further investigation into neural circuits.

14 Jul 2023

Unveiling the key defender: PLSCR1 identified as a potent anti-SARS-CoV-2 factor in COVID-19 immunity

Researchers identified the anti-SARS-CoV-2 function of phospholipid scramblase 1 (PLSCR1).

14 Jul 2023

INTEGRA pipetting solutions accelerate crucial viral genomics research

The Center for Emerging Viral Threats (CEVT) in Louisiana, USA, is using INTEGRA Biosciences’ liquid handling solutions for COVID-19 testing and viral genomics studies.

From INTEGRA Biosciences 14 Jul 2023

Using CRISPR gene-editing system to build a more sustainable forest

Researchers at North Carolina State University used a CRISPR gene-editing system to breed poplar trees with reduced levels of lignin, the major barrier to sustainable production of wood fibers, while improving their wood properties.

13 Jul 2023

Study finds highly specific polygenic signatures across multidimensional symptoms of bipolar disorder

Researchers analyzed the relationships between polygenic liability for bipolar disorder, schizophrenia, and major depressive disorder.

13 Jul 2023

Researchers develop a chemical approach to reverse aging

In a groundbreaking study, researchers have unlocked a new frontier in the fight against aging and age-related diseases.

12 Jul 2023

Plant cell study reveals new role for enzyme in lipid metabolism

A new study by Rice University bioscientists explains how basic cellular structures common to most life forms collaborate to fuel growth in a model plant organism. The findings could shed light on corresponding mechanisms in human cells.

12 Jul 2023

New heart cell atlas reveals detailed structure of the human heart

In a new study, published today (12 July) in Nature, researchers have produced the most detailed and comprehensive human Heart Cell Atlas to date, including the specialised tissue of the cardiac conduction system - where the heartbeat originates.

12 Jul 2023

Retrotransposons hijack cell's dna repair machinery to form circular DNA

Like its viral cousins, a somewhat parasitic DNA sequence called a retrotransposon has been found borrowing the cell's own machinery to achieve its goals.

12 Jul 2023

African cancer genome registry seeks to understand disparities in prostate, breast cancer risk and outcomes

"Please, please do it (cancer screening), if not for yourself, then for the next generation. We need to see the day when we end cancer."

11 Jul 2023

Whole genome sequencing shows promise for early diagnosis of genetic disorders in newborns, infants

A new national study, led by researchers at Tufts Medical Center in Boston, has found whole genome sequencing (WGS) to be nearly twice as effective as a targeted gene sequencing test at identifying abnormalities responsible for genetic disorders in newborns and infants.

11 Jul 2023

The genetics of neurogenic inflammation in rosacea

Researchers identify rare genetic variants in families with rosacea.

11 Jul 2023

PacBio's Revio long-read sequencing system to help Bioscientia solve complex genetic cases

PacBio, a leading developer of high-quality, highly accurate sequencing solutions, today announced that Bioscientia is using its Revio long-read sequencing system to expand its genomics research projects and sequence several thousand human genomes per year.

10 Jul 2023

Study traces the natural evolution of earliest stages of human cancers

Cancer cells-to-be accumulate a series of specific genetic changes in a predictable and sequential way years before they are identifiable as pre-malignancies, researchers at Stanford Medicine have found.

7 Jul 2023

MTB offers precision oncology strategy for advanced cancer patients

The collaborative group led by the Department of Clinical Oncology, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed) and the Division of Clinical Pathology & Molecular Pathology, Hong Kong Sanatorium & Hospital (HKSH), have recently published their findings on the clinical importance of the Multidisciplinary Molecular Tumour Board (MTB) in delivering a Precision Cancer Medicine service.

7 Jul 2023

Children with mitochondrial disorders have weaker antibody response to viral infections, study finds

In a new study, National Institutes of Health (NIH) researchers found that altered B cell function in children with mitochondrial disorders led to a weaker and less diverse antibody response to viral infections.

7 Jul 2023

Researchers show how communication networks in the tumor microenvironment promote cancer growth

Tumors consist of both the actual, malignant cancer cells and healthy, non-transformed cells in the immediate environment.

7 Jul 2023

Researchers identify an enzyme that plays a critical role in the late stages of HIV replication

Researchers at Johns Hopkins Medicine, in collaboration with researchers at the National Institutes of Health, report that two new studies in mice with a humanized immune system and human cell lines have identified an enzyme that plays a critical role in the late stages of HIV replication.

6 Jul 2023

COST Connect: A platform for collaboration and progress in cancer research

Beating cancer is a major challenge for research and innovation in the coming years. By 2030, it is estimated that over 1.5 million people in the EU will succumb to cancer.

6 Jul 2023

Sphere Fluidics expands Cyto-Mine capabilities to meet cGMP requirements for drug manufacture workflows

Sphere Fluidics, a company developing single cell analysis systems underpinned by its patented picodroplet technology, today announced updates to its flagship platform, Cyto-Mine®, enabling it to be compliant with current Good Manufacturing Practice (cGMP) regulations enforced by the US FDA.

From Fluidic Sciences and Sphere Bio 6 Jul 2023

Genome News and Research

Primate brain cell atlas provides molecular and cellular basis for neural circuit research

Unveiling the key defender: PLSCR1 identified as a potent anti-SARS-CoV-2 factor in COVID-19 immunity

INTEGRA pipetting solutions accelerate crucial viral genomics research

Using CRISPR gene-editing system to build a more sustainable forest

Study finds highly specific polygenic signatures across multidimensional symptoms of bipolar disorder

Researchers develop a chemical approach to reverse aging

Plant cell study reveals new role for enzyme in lipid metabolism

New heart cell atlas reveals detailed structure of the human heart

Retrotransposons hijack cell's dna repair machinery to form circular DNA

African cancer genome registry seeks to understand disparities in prostate, breast cancer risk and outcomes

Whole genome sequencing shows promise for early diagnosis of genetic disorders in newborns, infants

The genetics of neurogenic inflammation in rosacea

PacBio's Revio long-read sequencing system to help Bioscientia solve complex genetic cases

Study traces the natural evolution of earliest stages of human cancers

MTB offers precision oncology strategy for advanced cancer patients

Children with mitochondrial disorders have weaker antibody response to viral infections, study finds

Researchers show how communication networks in the tumor microenvironment promote cancer growth

Researchers identify an enzyme that plays a critical role in the late stages of HIV replication

COST Connect: A platform for collaboration and progress in cancer research

Sphere Fluidics expands Cyto-Mine capabilities to meet cGMP requirements for drug manufacture workflows

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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