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Structure function analysis of potent antibodies against Beta SARS-CoV-2 variant

A team of researchers from UK and US institutions created a large panel of mAbs derived from memory B cells of convalescent Beta subjects to better understand the antigenic landscape of Beta.

1 Dec 2021

Custom Biofluid & Tissue Procurement Service

Global provider of human and animal biospecimens - AMSBIO offers a custom procurement service enabling researchers to source specific biofluid and tissue samples which are not already available in their extensive biorepository.

From AMS Biotechnology 1 Dec 2021

New method helps correct genetic alterations in the cultured patient cells rapidly

Researchers in the University of Helsinki and University Hospital Helsinki have developed a method to precisely and rapidly correct genetic alterations in the cultured patient cells.

30 Nov 2021

SARS-CoV-2 Delta spike increases viral virulence and inflammatory cytokine production

In a new study published on the bioRxiv* preprint server, scientists investigated several virological features of the Delta spike protein.

29 Nov 2021

New phenotype of LRP6 mutation reported for the first time in patients with tooth agenesis

A group led by Prof. Han Dong of Peking University School of Stomatology reported for the first time hand preaxial polydactyly in patients with tooth agenesis carrying a previously unknown mutation of low-density lipoprotein receptor-related protein 6 (LRP6).

29 Nov 2021

Error rate of bacterial DNA polymerase is consistently higher under microgravity, study shows

On 22 May 2019, scientists from Queen's University boarded a modified Falcon 20 aircraft at Ottawa airport. Scheduled was a 'vomit comet' flight, where the plane repeatedly climbs to 8km in a steep parabola, alternating with a descent in freefall.

29 Nov 2021

Extended host range for SARS-CoV-2 variants of concern

Researchers used viral pseudotyping to examine whether variants of concern had different host ACE2 receptor usage patterns.

29 Nov 2021

Tomosyn protein's key contribution to heterogeneity of neurons revealed

The versatility of the nervous system comes from not only the diversity of ways in which neurons communicate in circuits, but also their "plasticity," or ability to change those connections when new information has to be remembered, when their circuit partners change, or other conditions emerge.

29 Nov 2021

Study uncovers mechanism for insensitivity to key antimalarial drug in new pathogen variant

Malaria is one of the most dangerous infectious diseases. The causative pathogens are microorganisms of the genus Plasmodium.

29 Nov 2021

Study suggests making COVID vaccines based on Mu variant

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Mu variant (B.1.621, B.1.621.1) has been tagged as a Variant Being Monitored (VBM), and as of August 30, 2021, it had been detected in 39 countries.

28 Nov 2021

Identifying the spread of novel B.1.1.523 SARS-CoV-2

In their recent study, researchers from Lithuania have reported the emergence of a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant lineage B.1.1.523 containing a set of mutations associated with immune escape, including deletion 156_158del, substitution E484K and S494P in Spike (S) protein.

28 Nov 2021

Low neutralizing antibody titers against SARS-CoV-2 Mu in BNT162b2 vaccinated

Researchers assess the neutralizing antibody titers in BNT162b2-vaccinated people against SARS-CoV-2 isolates from the Mu, Gamma, and B.1.111 lineages.

28 Nov 2021

The introduction and rapid spread of SARS-CoV-2 Gamma in Venezuela

Researchers from the Instituto Venezolano de Investigaciones Científica investigate the introduction of one of the VOCs into Venezuela.

28 Nov 2021

SARS-CoV-2 Omicron variant: What we know so far

On November 24, 2021, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron (B.1.1.529) variant was first reported to the World Health Organization (WHO) from South Africa.

28 Nov 2021

Prediction of severe infection based on SARS-CoV-2 genomic analysis

A group of researchers have used these SARS-CoV-2 sequence data and developed an algorithm to predict severity based upon viral mutations.

26 Nov 2021

Discovering a new gene in monkeys that could help to develop new antivirals

We spoke to Dr. Nels Elde about his latest research that led to the discovery of a new gene in monkeys that could help to develop new antivirals.

26 Nov 2021

Combination of two targeted drugs shows "clinically meaningful" activity in some malignant brain tumors

A combination of two targeted cancer drugs showed unprecedented, "clinically meaningful" activity in patients with highly malignant brain tumors that carried a rare genetic mutation, according to a clinical trial report by investigators from Dana-Farber Cancer Institute.

25 Nov 2021