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Study explains how bacterial biofilms expand to form slimy mats on teeth, surgical instruments

New research at Harvard explains how bacterial biofilms expand to form slimy mats on teeth, pipes, surgical instruments, and crops.

23 Jan 2012

Researchers discover 13 new regions of genome associated with timing of menopause

An international team of researchers has discovered 13 new regions of the genome associated with the timing of menopause. These genes shed light on the biological pathways involved in reproductive lifespan and will provide insights into conditions connected to menopause, such as breast cancer and heart disease.

23 Jan 2012

Scientists discover finely tuned mechanism associated with CHD

Scientists at the Gladstone Institutes have identified a finely tuned mechanism by which fetal heart muscle develops into a healthy and fully formed beating heart-offering new insight into the genetic causes of congenital heart disease and opening the door to one day developing therapies to fight this chronic and potentially fatal disorder.

23 Jan 2012

Chronic inflammation combines with DNA methylation to promote development of colorectal cancer

Chronic inflammation combines with DNA methylation, a process that shuts down cancer-fighting genes, to promote development of colorectal cancer, scientists at The University of Texas MD Anderson Cancer Center report today in the advance online publication of the journal Nature Medicine.

23 Jan 2012

Genes may predict maintenance of intelligence over lifetime: Study

A Scottish study that began 80 years ago has shown that genes may play a role in maintaining intelligence till old age. The study participants joined when they were 11 years old. Researchers have long been interested in understanding how cognition changes with age, and why these changes are more rapid in some people than in others. But, in the past, studies of age-related intelligence changes were often performed when the subjects were already elderly.

22 Jan 2012

Three-parent children may be born in near future in an effort to combat mitochondrial diseases

In the next couple of years the scientific community may witness creation of children with genetic material from three parents. British scientists want to start testing a new IVF technique to try to eradicate incurable genetic diseases such as muscular dystrophy. The concept took a leap forward yesterday after the Government announced a public consultation on whether the law should be changed to allow the technique.

22 Jan 2012

First genome-wide study of high-altitude adaptations in Ethiopians

Over many generations, people living in the high-altitude regions of the Andes or on the Tibetan Plateau have adapted to life in low-oxygen conditions. Living with such a distinct and powerful selective pressure has made these populations a textbook example of evolution in action, but exactly how their genes convey a survival advantage remains an open question. Now, a University of Pennsylvania team has made new inroads to answering this question with the first genome-wide study of high-altitude adaptations within the third major population to possess them: the Amhara people of the Ethiopian Highlands.

21 Jan 2012

New tool to improve ease of oral fluid collection

Researchers are constantly finding new ways to figure out what makes us human beings tick, and one of the newer methods makes you want to spit—literally. Saliva is full of analytes and biomarkers that create a biological journal of exposure to chemicals and disease, and genetic variability. However, the collection of oral fluid has always proved cumbersome, with researchers depending on swabs or collection cups.

21 Jan 2012

Presidential Commission for the Study of Bioethical Issues to hold public meeting in San Francisco

The Presidential Commission for the Study of Bioethical Issues will hold a public meeting February 2-3 in San Francisco, CA.

21 Jan 2012

NCI-funded project aims to shed new light on implications for bone metastasis in prostate cancer

Prostate cancer is the most frequent and second deadliest cancer men face. A team of Wayne State University researchers recently received $363,660 from the National Cancer Institute of the National Institutes of Health for the project - "Bone-induced c-kit in prostate cancer cells: implications for bone metastasis" - that aims to shed new light on implications for bone metastasis in prostate cancer.

21 Jan 2012

ARCA biopharma receives method patent for treatment with bucindolol based on genetic targeting

ARCA biopharma, Inc., a biopharmaceutical company developing genetically targeted therapies for cardiovascular diseases, today announced that the U.S. Patent and Trademark Office has issued a patent on methods for determining whether to administer or prescribe bucindolol to a patient based on whether the patient has a specific genotype - homozygous for the arginine 389 polymorphism in the beta-1 adrenergic receptor.

20 Jan 2012

RHBDF2 gene plays a key role in growth of oesophageal cancer

New research from Queen Mary, University of London has uncovered a gene which plays a key role in the development of oesophageal cancer.

20 Jan 2012

MSC-mediated RNAi transfer holds promise for Huntington's disease

A team of researchers at the UC Davis Institute for Regenerative Cures has developed a technique for using stem cells to deliver therapy that specifically targets the genetic abnormality found in Huntington's disease, a hereditary brain disorder that causes progressive uncontrolled movements, dementia and death.

20 Jan 2012

Defect in neuronal RNA splicing process may contribute to neurological disease

A Jackson Laboratory research team led by Professor and Howard Hughes Medical Investigator Susan Ackerman, Ph.D., has discovered a defect in the RNA splicing process in neurons that may contribute to neurological disease.

20 Jan 2012

Distal-less gene plays a critical role in development of fruit fly olfactory system

Fruit flies don't have noses, but a huge part of their brains is dedicated to processing smells. Flies probably rely on the sense of smell more than any other sense for essential activities such as finding mates and avoiding danger. UW-Madison researchers have discovered that a gene called distal-less is critical to the fly's ability to receive, process and respond to smells.

20 Jan 2012

Researchers reveal role of micronuclei in cancer process

They are the Robinson Crusoes of the intracellular world -- lone chromosomes, whole and hardy, stranded outside the nucleus where their fellow chromosomes reside. Such castaways, each confined to its own "micronucleus," are often found in cancer cells, but scientists haven't known what role, if any, they play in the cancer process.

20 Jan 2012

Study explains gender-related incidence of liver cancer

Men are four times more likely to develop liver cancer compared to women, a difference attributed to the sex hormones androgen and estrogen. Although this gender difference has been known for a long time, the molecular mechanisms by which estrogens prevent -- and androgens promote -- liver cancer remain unclear.

20 Jan 2012

Birth weight plays a role in autism spectrum disorder

Although the genetic basis of autism is now well established, a growing body of research also suggests that environmental factors may play a role in this serious developmental disorder affecting nearly one in 100 children. Using a unique study design, a new study suggests that low birth weight is an important environmental factor contributing to the risk of autism spectrum disorder.

20 Jan 2012

Anabolic steroids do not appear to contribute to CTE

Anabolic steroids don't appear to contribute to degenerative brain disease caused by repeated head trauma in athletes, according to a study in the January issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

20 Jan 2012

Earlier detection of Fragile X syndrome made possible

Now families children with fragile X syndrome may have a chance of earlier detection and intervention. The Murdoch Children's Research Institute breakthrough could allow newborn screening of the world's most common cause of inherited developmental disability. The research findings were published in the journal Clinical Chemistry.

19 Jan 2012

Genetic News and Research

Study explains how bacterial biofilms expand to form slimy mats on teeth, surgical instruments

Researchers discover 13 new regions of genome associated with timing of menopause

Scientists discover finely tuned mechanism associated with CHD

Chronic inflammation combines with DNA methylation to promote development of colorectal cancer

Genes may predict maintenance of intelligence over lifetime: Study

Three-parent children may be born in near future in an effort to combat mitochondrial diseases

First genome-wide study of high-altitude adaptations in Ethiopians

New tool to improve ease of oral fluid collection

Presidential Commission for the Study of Bioethical Issues to hold public meeting in San Francisco

NCI-funded project aims to shed new light on implications for bone metastasis in prostate cancer

ARCA biopharma receives method patent for treatment with bucindolol based on genetic targeting

RHBDF2 gene plays a key role in growth of oesophageal cancer

MSC-mediated RNAi transfer holds promise for Huntington's disease

Defect in neuronal RNA splicing process may contribute to neurological disease

Distal-less gene plays a critical role in development of fruit fly olfactory system

Researchers reveal role of micronuclei in cancer process

Study explains gender-related incidence of liver cancer

Birth weight plays a role in autism spectrum disorder

Anabolic steroids do not appear to contribute to CTE

Earlier detection of Fragile X syndrome made possible

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