Cell Death News and Research

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Drug used to treat bipolar disorder may help prevent brain cell damage in TBI patients

A drug used to treat bipolar disorder and other forms of depression may help to preserve brain function and prevent nerve cells from dying in people with a traumatic brain injury, according to a new Rutgers University study.

8 May 2017

Researchers pinpoint gene that plays crucial role in formation of neural tube defects

Researchers have identified a gene that plays a key role in the formation of neural tube defects, a problem commonly found in infants of pregnant women with diabetes.

5 May 2017

TSRI scientists uncover regulatory machinery underlying the function of cancer protein

Despite intense research, there's been much confusion regarding the exact role of a protein in a critical cancer-linked pathway. On one hand, the protein is described as a cell proliferation inhibitor, on the other, a cell proliferation activator, a duality that has caused a great deal of scientific head scratching.

5 May 2017

Easing cellular traffic jams in Huntington’s disease may save brain cells

Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center - the nucleus- appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.

5 May 2017

Researchers identify biomarker that could predict disease severity in glaucoma patients

Glaucoma, a leading cause of blindness worldwide, most often is diagnosed during a routine eye exam. Over time, elevated pressure inside the eye damages the optic nerve, leading to vision loss. Unfortunately, there's no way to accurately predict which patients might lose vision most rapidly.

4 May 2017

New research uncovers role of mysterious molecule in skin cancer

New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) at Lake Nona uncovers the modus operandi of a mysterious molecule called SPRIGHTLY that has been previously implicated in colorectal cancer, breast cancer, and melanoma.

3 May 2017

IDIBELL researchers reveal role of endoplasmic reticulum in cell death process due to starvation

Researchers from the Cell death group of the Bellvitge Biomedical Research Institute, led by Dr. Cristina Muñoz-Pinedo, have characterized the cell death process due to starvation, in which the endoplasmic reticulum plays a leading role.

3 May 2017

Researchers show how Epstein-Barr virus manages to persist inside immune system's B cells

Viruses are notorious for taking over their host's operations and using them to their own advantage. But few human viruses make themselves quite as cozy as the Epstein-Barr virus, which can be found in an estimated nine out of ten humans without causing any ill effects.

3 May 2017

Combination therapy may be effective option for treating some women with ovarian cancer

Researchers have been trying to understand why up to 85 percent of women experience recurrence of high-grade serous ovarian cancer -- the most common subtype of ovarian cancer -- after standard treatment with the chemotherapy drug carboplatin.

2 May 2017

Simple eye test can diagnose early signs of glaucoma

A SIMPLE eye test could help solve the biggest global cause of irreversible blindness, glaucoma. In clinical trials, the pioneering diagnostic -- developed by researchers at University College London and the Western Eye Hospital -- allowed doctors to see individual nerve cell death in the back of the eye.

27 Apr 2017

Study underscores need for genetic screening to improve safety of experimental stem cell treatments

Regenerative medicine using human pluripotent stem cells to grow transplantable tissue outside the body carries the promise to treat a range of intractable disorders, such as diabetes and Parkinson's disease.

26 Apr 2017

Engineered nanosponges can reduce severity of infections caused by group A Streptococcus

In a new study, researchers show that engineered nanosponges that are encapsulated in the membranes of red blood cells can reduce the severity of infections caused by group A Streptococcus, the bacteria responsible for strep throat and life-threatening infections such as necrotizing fasciitis, or flesh-eating disease.

25 Apr 2017

Researchers discover cancer-fighting properties in beta blockers

A new study finds that carvedilol, a drug typically used to treat high blood pressure, can protect against the sun-induced cell damage that leads to skin cancer. Researchers serendipitously discovered the beta blocker's cancer-fighting properties after making an error in the lab.

24 Apr 2017

Researchers show how fish oil component helps in survival of injured retina, brain cells

A team of researchers led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health New Orleans School of Medicine, has shown for the first time that NDP1, a signaling molecule made from DHA, can trigger the production of a protective protein against toxic free radicals and injury in the brain and retina.

21 Apr 2017

Johns Hopkins study shows that healthy adult gut loses and regenerates nerve cells

Johns Hopkins researchers today published new evidence refuting the long-held scientific belief that the gut nerve cells we're born with are the same ones we die with.

19 Apr 2017

TUM study shows link between zinc supply in the body and cardiac function

In addition to essential metabolic functions, the level of zinc in the body also affects the heart muscle. When oxidative stress occurs, it may be due to a shortage of zinc, which can be determined by examining the heart muscle.

18 Apr 2017

Combination of anti-angiogenic and immune-stimulating therapies can lead to effective cancer treatments

Scientists from VIB and KU Leuven, together with colleagues from the University of California and the Swiss Institute for Experimental Cancer Research have demonstrated that, anti-angiogenic therapy can improve immune boosting treatments.

13 Apr 2017

Study may provide insight into how R-LA promotes death of hepatoma cells

A new study that measured metabolite levels over time in starved rat liver cancer cells showed that treatment with a form of alpha-lipoic acid (LA) inhibited glucose uptake and glycolysis, and led to decreased cellular glucose production from non-carbohydrate sources, which may help explain how the naturally occurring R enantiomeric form of LA (R-LA) promotes the death of hepatoma cells.

12 Apr 2017

New study finds link between neural tube defects in infants and neurodegenerative diseases

A new study has found a link between neurological birth defects in infants commonly found in pregnant women with diabetes and several neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases.

10 Apr 2017

Research finding could offer new way to fight deadly pancreatic cancer

Pancreatic cancer, most frequently pancreatic ductal adenocarcinoma (PDAC), is the most lethal and aggressive of all cancers. Unfortunately, there are not many effective therapies available other than surgery, and that is not an option for many patients.

10 Apr 2017

Cell Death News and Research

Drug used to treat bipolar disorder may help prevent brain cell damage in TBI patients

Researchers pinpoint gene that plays crucial role in formation of neural tube defects

TSRI scientists uncover regulatory machinery underlying the function of cancer protein

Easing cellular traffic jams in Huntington’s disease may save brain cells

Researchers identify biomarker that could predict disease severity in glaucoma patients

New research uncovers role of mysterious molecule in skin cancer

IDIBELL researchers reveal role of endoplasmic reticulum in cell death process due to starvation

Researchers show how Epstein-Barr virus manages to persist inside immune system's B cells

Combination therapy may be effective option for treating some women with ovarian cancer

Simple eye test can diagnose early signs of glaucoma

Study underscores need for genetic screening to improve safety of experimental stem cell treatments

Engineered nanosponges can reduce severity of infections caused by group A Streptococcus

Researchers discover cancer-fighting properties in beta blockers

Researchers show how fish oil component helps in survival of injured retina, brain cells

Johns Hopkins study shows that healthy adult gut loses and regenerates nerve cells

TUM study shows link between zinc supply in the body and cardiac function

Combination of anti-angiogenic and immune-stimulating therapies can lead to effective cancer treatments

Study may provide insight into how R-LA promotes death of hepatoma cells

New study finds link between neural tube defects in infants and neurodegenerative diseases

Research finding could offer new way to fight deadly pancreatic cancer

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