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Chemical drug safely controls side effects associated with haploidentical stem cell transplantation

Researchers in the Center for Cell and Gene Therapy at Baylor College of Medicine, Houston Methodist and Texas Children's Hospital have found that a single dose of an otherwise harmless drug can safely control the severe and often lethal side effects associated with haploidentical stem cell transplantation.

15 May 2015

Researchers explore how low-level electrical stimulation reduces inflammation

The Feinstein Institute for Medical Research, the research arm of the North Shore-LIJ Health System, and SetPoint Medical Inc., a biomedical technology company, today released the results of research on the therapeutic potential of vagus nerve stimulation. In a paper published by Bioelectronic Medicine, Kevin J. Tracey, MD, and his colleagues at the Feinstein Institute, explore how low-level electrical stimulation interacts with the body's nerves to reduce inflammation, a fundamental goal of bioelectronic medicine.

15 May 2015

APS announces recipients of prestigious achievement awards during annual scientific meeting

The American Pain Society (APS), www.americanpainsociety.org, today announced the recipients of its prestigious achievement awards during the organization's annual scientific meeting.

14 May 2015

Immune system plays surprising role in the progression of Rett syndrome

New research by investigators at the University of Massachusetts Medical School suggests the immune system plays an unsuspected and surprising role in the progression of Rett syndrome, a severe neurological disorder affecting children. Immune cells known as macrophages are unable to perform their normal function and are instead amplifying the disease.

11 May 2015

Small ion pump gives new hope for severe nerve pain sufferers

A small ion pump in organic electronics is giving new hope to people suffering from severe nerve pain. Researchers at Swedish Linköping University and the Karolinska Institute are the first in the world with technology that can stop pain impulses in living, freely moving rats using the body's own pain relief signals.

11 May 2015

Gene therapy is key to addressing Sanfilippo Syndrome, say Ohio scientists and clinicians

Gene therapy is the delivery of DNA into a patient's cells to replace faulty or missing genes—or adds new genes—in an attempt to cure cancer or make changes so the body is better able to fight off disease. Scientists and clinicians have identified a number of different ways to do this, in an effort to correct malfunctioning or mutated genes. Many gene therapy clinical trials are ongoing to assess the safety and potential benefits in patients with rare diseases.

8 May 2015

Obesity and depression play role in excessive daytime sleepiness

Obesity and depression -- not only lack of sleep -- are underlying causes for regular drowsiness, according to Penn State College of Medicine researchers. They say these findings could lead to more personalized sleep medicine for those with excessive daytime sleepiness (EDS).

8 May 2015

Proteomics helps identify previously unrecognized proteins and pathways in nerve regeneration

Using proteomics techniques to study injured optic nerves, researchers at Boston Children's Hospital have identified previously unrecognized proteins and pathways involved in nerve regeneration. Adding back one of these proteins--the oncogene c-myc--they achieved unprecedented optic nerve regeneration in mice when combined with two other known strategies.

5 May 2015

Scientists report that enzyme that alters testosterone to estrogen has big impact in healthy, injured brain

An enzyme that converts testosterone to estrogen appears to have significant impact in a healthy and injured brain, scientists report.

5 May 2015

DelMar to present new data on development of VAL-083 at 2015 ASCO Annual Meeting

DelMar Pharmaceuticals, Inc., today announced that it will be presenting new data related to the development of lead product candidate VAL-083 (dianhydrogalactitol) at the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, being held May 29-June 2, 2015, in Chicago, Illinois.

30 Apr 2015

ITIM-containing receptor crucial for development of acute myeloid leukemia

UT Southwestern Medical Center scientists have discovered that a certain class of receptors that inhibit immune response are crucial for the development of acute myeloid leukemia (AML), the most common acute leukemia affecting adults.

30 Apr 2015

Cytokine GM-CSF likely plays important role in MS

Multiple sclerosis (MS) is caused by immune cells that activate a cascade of chemicals in the brain, attacking and degrading the insulation that keeps neuronal signals moving. These chemicals, called cytokines, drive the inflammation in the brain, attracting more immune cells, and causing the debilitating disease marked by loss of neurological function.

30 Apr 2015

Oncologists need to screen tumor patients for depression

Because depression in brain cancer patients is a common but often overlooked condition, oncologists should regularly screen tumor patients for depression, according to an article in the current issue of CNS Oncology. The journal is published by Future Medicine, an imprint of Future Science Group.

30 Apr 2015

Plastic surgeons find association between carpal tunnel syndrome and migraine headache

Plastic surgeons at UT Southwestern Medical Center have demonstrated for the first time an association between migraines and carpal tunnel syndrome, with migraines more than twice as prevalent in those with carpal tunnel syndrome as those without, according to the study.

28 Apr 2015

UC Davis researchers settle long-standing controversy surrounding Canavan disease

UC Davis investigators have settled a long-standing controversy surrounding the molecular basis of an inherited disorder that historically affected Ashkenazi Jews from Eastern Europe but now also arises in other populations of Semitic descent, particularly families from Saudi Arabia.

28 Apr 2015

Increasing radiotherapy can significantly improve survival for children with intracranial ependymoma

Two studies to be presented today (Sunday) at the 3rd ESTRO Forum in Barcelona, Spain, show that increasing the dose of radiotherapy given to children with an intracranial ependymoma, a form of cancer of the central nervous system, can significantly improve their survival.

27 Apr 2015

Dr. Mike O. Karl awarded EYEnovative Research Award for retina research

Dr. Mike O. Karl, group leader at the German Center for Neurodegenerative Diseases and the DFG Research Center for Regenerative Therapies Dresden - Cluster of Excellence at the TU Dresden, was awarded the “EYEnovative Förderpreis” of the Novartis Pharma GmbH already for the second time.

25 Apr 2015

Several drugs could lead to new MS treatment options

New research published this week in Nature has found several drugs could lead to new treatment options for multiple sclerosis (MS), including two drugs that effectively treat MS at the source, in vivo. When administered at the peak of disease, these two drugs showed a striking reversal of disease severity.

23 Apr 2015

New research examines what happens when MS patients discontinue their medication

New research led by NYU Langone Medical Center examines what happens when a patient with multiple sclerosis (MS) who is clinically stable stops taking their medication.

22 Apr 2015

Statistical analyses identifies higher-than-expected rates of pediatric cancers in 2 Florida areas

Higher-than-expected rates of pediatric cancers have been identified in the Miami metro area and an area west of the Everglades in a series of five statistical analyses conducted for Science and Public Policy, an open-access, online public-policy journal published by the American Statistical Association.

21 Apr 2015

Central Nervous System News and Research

Chemical drug safely controls side effects associated with haploidentical stem cell transplantation

Researchers explore how low-level electrical stimulation reduces inflammation

APS announces recipients of prestigious achievement awards during annual scientific meeting

Immune system plays surprising role in the progression of Rett syndrome

Small ion pump gives new hope for severe nerve pain sufferers

Gene therapy is key to addressing Sanfilippo Syndrome, say Ohio scientists and clinicians

Obesity and depression play role in excessive daytime sleepiness

Proteomics helps identify previously unrecognized proteins and pathways in nerve regeneration

Scientists report that enzyme that alters testosterone to estrogen has big impact in healthy, injured brain

DelMar to present new data on development of VAL-083 at 2015 ASCO Annual Meeting

ITIM-containing receptor crucial for development of acute myeloid leukemia

Cytokine GM-CSF likely plays important role in MS

Oncologists need to screen tumor patients for depression

Plastic surgeons find association between carpal tunnel syndrome and migraine headache

UC Davis researchers settle long-standing controversy surrounding Canavan disease

Increasing radiotherapy can significantly improve survival for children with intracranial ependymoma

Dr. Mike O. Karl awarded EYEnovative Research Award for retina research

Several drugs could lead to new MS treatment options

New research examines what happens when MS patients discontinue their medication

Statistical analyses identifies higher-than-expected rates of pediatric cancers in 2 Florida areas

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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