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Scientists discover key age-related biological shifts at 40 and 60

Researchers uncover the nonlinear dynamics of aging, revealing significant biological shifts at ages 40 and 60, offering new insights into age-related diseases.

16 Aug 2024

Saliva test offers hope for head and neck cancer patients

But what if a mouthwash-based test to detect biomarkers can help physicians predict disease recurrence in head and neck cancer patients?

16 Aug 2024

Neoadjuvant immunotherapy yields comparable outcomes in high-risk liver cancer surgery

Patients with liver cancer who received immune checkpoint inhibitors (ICIs) before surgery - including those who would not have been eligible for surgery by conventional criteria - had similar outcomes to patients who received surgery upfront, according to results from a retrospective study.

15 Aug 2024

Groundbreaking study uncovers new genetic variants linked to normal pressure hydrocephalus

A new study by the University of Eastern Finland and partners identified new genetic variants associated with normal pressure hydrocephalus (NPH).

15 Aug 2024

The FDA calls them ‘recalls,’ yet the targeted medical devices often remain in use

In 2016, medical device giant Abbott issued a recall for its MitraClip cardiac device — "a Class I recall, the most serious type," the FDA said.

15 Aug 2024

Early detection key to beating ovarian cancer

'Symptom triggered testing', prompted by symptoms such as pain, abdominal bloating/swelling, and feeling full soon after starting to eat, can pick up early stage aggressive ovarian cancer in 1 in 4 of those affected, finds a data analysis, published online in the International Journal of Gynecological Cancer.

14 Aug 2024

World's first rapid TBI blood test debuts at Orlando Health

Orlando Health Orlando Regional Medical Center (ORMC) is the first hospital in the world to use a new, groundbreaking blood test to help assess patients with suspected mild traumatic brain injuries (TBIs), or concussions.

13 Aug 2024

IU research sheds light on urea cycle defects and fatty liver disease

An Indiana University School of Medicine physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States.

13 Aug 2024

Early detection of cardiovascular diseases using advanced machine learning

How can diseases of the cardiovascular system be detected before symptoms appear? Researchers at Graz University of Technology (TU Graz) have found a way to track them down at an early stage.

13 Aug 2024

New antibody treatment shows promise in preventing heart transplant rejection

A new study from scientists at Cincinnati Children's suggests there may be a way to further protect transplanted hearts from rejection by preparing the donor organ and the recipient with an anti-inflammatory antibody treatment before surgery occurs.

12 Aug 2024

Novel exosome-based drug delivery system for synergistic cancer treatment

Ovarian cancer is one of the most common malignancies in women worldwide. Unlike breast cancer, ovarian cancer lacks early diagnostic markers and does not show noticeable symptoms until cancer metastases, leading to a low survival rate for ovarian cancer patients.

12 Aug 2024

Engineered NK cells with IL-21 show strong antitumor activity against glioblastoma

Natural killer (NK) cells engineered to express interleukin-21 (IL-21) demonstrated sustained antitumor activity against glioblastoma stem cell-like cells (GSCs) both in vitro and in vivo, according to new research from The University of Texas MD Anderson Cancer Center.

12 Aug 2024

Does cannabis use disorder increase the risk of head and neck cancer?

Researchers determine whether cannabis use disorder increases the risk of head and neck cancer.

12 Aug 2024

Salpingectomy during sterilization can be a safe option to reduce ovarian cancer risk

Women whose Fallopian tubes are removed during sterilization via laparoscopy have only marginally more surgical complications than those whose tubes are simply cut, a study shows.

11 Aug 2024

VA Disrupted Care National Project reveals ongoing decline in vascular surgeries post-pandemic

Recently published findings from the VA Disrupted Care National Project (DCNP) revealed the number of vascular surgeries performed across the United States continued to decline even after large drops during the COVID-19 pandemic.

9 Aug 2024

Medi-Cal’s dental care gap: Getting a tooth pulled is easy — much harder to get an implant

When Bobby Moske went to a community clinic a few years ago with a toothache, he couldn't find a dentist in Marin County willing to take Medicaid to do a root canal.

9 Aug 2024

Discovery of progenitor exhausted T cells offers hope for cancer patients

Tumor immunotherapy leverages the body's immune system to target and eradicate cancer cells, offering a crucial treatment for patients unresponsive to surgery or conventional therapies. Despite its potential, the effectiveness of immunotherapy is often hindered by T cell exhaustion within the tumor microenvironment, leading to diminished immune response and tumor progression. Based on these challenges, exploring the role of progenitor exhausted T cells (Tpex) in overcoming immune resistance is essential for advancing immunotherapeutic strategies and improving clinical outcomes.

8 Aug 2024

Insilico Medicine's pan-TEAD inhibitor ISM6331 receives FDA IND clearance for mesothelioma treatment

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced ISM6331, potential best-in-class pan-TEAD inhibitor, has received the U.S. Food and Drug Administration (FDA) Investigational New Drug (IND) clearance for the treatment of mesothelioma, following the grant of Orphan Drug Designation (ODD) in June 2024. It brings the total number of IND-approved molecules of Insilico to nine.

8 Aug 2024

Alcohol use in older adults linked to increased risk of severe head trauma after falls

Nationally, falls remain the leading cause of both fatal and non-fatal injuries in older adults and are the leading cause of traumatic brain injury.

8 Aug 2024

Drug shows new promise in treating breast cancer with brain metastases or recurrent glioblastoma

A drug effective in treating breast cancer shows new promise in addressing breast cancer with brain metastases or recurrent glioblastoma, as reported by results of a prospective window-of-opportunity trial at the University of Texas Health Science Center at San Antonio (UT Health San Antonio).

8 Aug 2024

Surgery News and Research

Scientists discover key age-related biological shifts at 40 and 60

Saliva test offers hope for head and neck cancer patients

Neoadjuvant immunotherapy yields comparable outcomes in high-risk liver cancer surgery

Groundbreaking study uncovers new genetic variants linked to normal pressure hydrocephalus

The FDA calls them ‘recalls,’ yet the targeted medical devices often remain in use

Early detection key to beating ovarian cancer

World's first rapid TBI blood test debuts at Orlando Health

IU research sheds light on urea cycle defects and fatty liver disease

Early detection of cardiovascular diseases using advanced machine learning

New antibody treatment shows promise in preventing heart transplant rejection

Novel exosome-based drug delivery system for synergistic cancer treatment

Engineered NK cells with IL-21 show strong antitumor activity against glioblastoma

Does cannabis use disorder increase the risk of head and neck cancer?

Salpingectomy during sterilization can be a safe option to reduce ovarian cancer risk

VA Disrupted Care National Project reveals ongoing decline in vascular surgeries post-pandemic

Medi-Cal’s dental care gap: Getting a tooth pulled is easy — much harder to get an implant

Discovery of progenitor exhausted T cells offers hope for cancer patients

Insilico Medicine's pan-TEAD inhibitor ISM6331 receives FDA IND clearance for mesothelioma treatment

Alcohol use in older adults linked to increased risk of severe head trauma after falls

Drug shows new promise in treating breast cancer with brain metastases or recurrent glioblastoma

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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