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Johns Hopkins scientists safely use immune cells to treat multiple myeloma

In a report on what is believed to be the first small clinical trial of its kind, researchers at the Johns Hopkins Kimmel Cancer Center say they have safely used immune cells grown from patients' own bone marrow to treat multiple myeloma, a cancer of white blood cells.

21 May 2015

Magstim Announces FDA (510k) Clearance of rTMS (repetitive Transcranial Magnetic Stimulation) Therapy System

Magstim is the pioneer of TMS technology, having built a reputation for developing leading medical devices in the research field for over 25 years. ..

From Magstim 21 May 2015

SARIL-RA-TARGET trial: Sarilumab meets co-primary efficacy endpoints in RA patients

Regeneron Pharmaceuticals, Inc. and Sanofi announced today that a Phase 3 study of sarilumab, an investigational, fully human IL-6 receptor antibody, met its co-primary efficacy endpoints of a greater improvement in signs and symptoms of rheumatoid arthritis (RA) at 24 weeks and physical function at 12 weeks, compared to placebo.

21 May 2015

RepliCel's autologous cell treatment for Achilles tendinosis to be presented at ISCT 2015

RepliCel Life Sciences Inc., a clinical stage regenerative medicine company focused on the development of autologous cell therapies, announced today an upcoming poster presentation at the International Society for Cellular Therapy on RepliCel's autologous cell treatment for chronic Achilles tendinosis currently in a Phase 1/2 clinical trial.

21 May 2015

New research project aims to improve music listening experiences in people with hearing impairments

Beethoven composed some of his most famous works after he became profoundly deaf. More recently, musicians such as Ozzy Osbourne, Brian Wilson and Phil Collins have encountered problems with their hearing. Tinnitus affects many more, from Eric Clapton and Neil Young to will.i.am.

21 May 2015

Novel drug target identified for treating rheumatoid arthritis

Researchers at the La Jolla Institute for Allergy and Immunology, in collaboration with colleagues the University of California, San Diego, identified a novel drug target for the treatment of rheumatoid arthritis that focuses on the cells that are directly responsible for the cartilage damage in affected joints.

21 May 2015

Researchers find that blocking MCAM molecule could slow progression of multiple sclerosis

A drug that could halt the progression of multiple sclerosis may soon be developed thanks to a discovery by a team at the CHUM Research Centre and the University of Montreal. The researchers have identified a molecule called MCAM, and they have shown that blocking this molecule could delay the onset of the disease and significantly slow its progression.

21 May 2015

Non-coding micro RNA molecule may control chemotherapy resistance among ovarian cancer patients

A molecule that helps control gene expression may play a role in controlling chemotherapy resistance among patients with the most common form of ovarian cancer.

21 May 2015

Scripps Proton Therapy Center reports exceptional results in treating patients with pencil-beam scanning

The nation's first and only proton therapy center to treat patients exclusively with pencil-beam scanning is reporting exceptional results in delivering cancer treatment since opening for patient care just more than a year ago.

21 May 2015

Anti-VEGF therapy benefits in wet AMD not sustained

Real-world experience of anti-vascular endothelial growth factor therapy for patients with wet age-related macular degeneration suggests that initial improvements in visual acuity are not maintained over time.

20 May 2015

Stereotactic body radiotherapy appears to be safe, effective for some pancreatic cancer patients

Two studies from Johns Hopkins Kimmel Cancer Center researchers add to preliminary evidence that high-dose radiation treatment, called stereotactic body radiotherapy, appears to be safe and as effective as standard radiation treatment for certain patients with pancreatic cancer whose tumors are advanced but have not spread.

20 May 2015

Zona Plus isometric handgrip device now available in Canada for patients with high blood pressure

The Zona Plus isometric handgrip device ("Zona Plus") which combines personalized technology and an easy-to-follow 12 minutes per day, five days per week routine for patients with high blood pressure is now available in Canada.

20 May 2015

Johns Hopkins researchers identify new therapy to treat lung cancer

A multidisciplinary team led by Johns Hopkins researcher Venu Raman, Ph.D., with notable contributions from Guus Bol, Farhad Vesuna and Phuoc Tran of Johns Hopkins, has identified a new therapy for lung cancer, the most common cancer worldwide. The therapy has been in development for six years and involves a first-in-class molecule designed by the team.

20 May 2015

Magstim Rapid2 Therapy System receives FDA clearance for treatment of drug resistant MDD

The Magstim Company Ltd, an innovative and award winning Wales-based medical device manufacturer, has received FDA 510(k) clearance to market its Magstim Rapid2 Therapy System for the treatment of drug resistant Major Depressive Disorder (MDD) in the United States. The clearance enables Magstim to significantly increase access to cutting-edge Repetitive Transcranial Magnetic Stimulation (rTMS) technology for patients and clinicians.

From Magstim 20 May 2015

Similar diabetic macular oedema outcomes with deferred vs prompt laser therapy

Visual acuity outcomes are comparable in diabetic macular oedema patients who receive laser treatment 24 weeks or more after initiation of ranibizumab injections and those for whom laser therapy is initiated concurrently, show the 5-year results of a US study.

19 May 2015

MedVantx launches MedStart Formulary Connect program for health systems and ACOs

MedVantx, Inc., a leading provider of point-of-care medication access, adherence and direct-to-patient consumer engagement programs, today announced the Company's MedStart Formulary Connect program. This innovative program equips leading health systems and ACOs with new formulary management tools that are designed to build greater alignment and advance the traditional medication formulary program upstream in the value chain to the point of care.

19 May 2015

DNAtrix signs agreement to utilize Alcyone's MEMS platform for direct drug delivery into glioblastoma

Alcyone Lifesciences, Inc., a leader in neural intervention systems for neurological conditions and targeted drug delivery, and DNAtrix Inc., a privately held biotechnology company and a leader in oncolytic virus therapy, have entered into an exclusive clinical collaboration. Under the agreement, DNAtrix will utilize Alcyone's MEMS Cannula (AMC) targeted delivery platform for the intratumoral delivery of DNX-2401, an oncolytic adenovirus and DNAtrix's lead product for the treatment of the most aggressive form of brain cancer, glioblastoma (GBM).

19 May 2015

Vitamin E helps build strong muscles

Body builders have it right: vitamin E does help build strong muscles, and scientists appear to have figured out one important way it does it.

19 May 2015

Current menopausal hormone therapy users at increased risk of experiencing GI bleeding

Current users of menopausal hormone therapy (MHT) are more than twice as likely than non-users to develop lower gastrointestinal bleeding and ischemic colitis, especially if they use the therapy for longer durations, according to a study at Digestive Disease Week 2015.

19 May 2015

Naldemedine shows promise in treating OIC in patients with chronic non-cancer pain.

Shionogi Inc. today announced data from a Phase IIb study that showed 0.2 mg and 0.4 mg of naldemedine demonstrated statistically significant efficacy in treating opioid-induced constipation (OIC) in patients with chronic non-cancer pain.

19 May 2015

Therapy News and Research

Johns Hopkins scientists safely use immune cells to treat multiple myeloma

Magstim Announces FDA (510k) Clearance of rTMS (repetitive Transcranial Magnetic Stimulation) Therapy System

SARIL-RA-TARGET trial: Sarilumab meets co-primary efficacy endpoints in RA patients

RepliCel's autologous cell treatment for Achilles tendinosis to be presented at ISCT 2015

New research project aims to improve music listening experiences in people with hearing impairments

Novel drug target identified for treating rheumatoid arthritis

Researchers find that blocking MCAM molecule could slow progression of multiple sclerosis

Non-coding micro RNA molecule may control chemotherapy resistance among ovarian cancer patients

Scripps Proton Therapy Center reports exceptional results in treating patients with pencil-beam scanning

Anti-VEGF therapy benefits in wet AMD not sustained

Stereotactic body radiotherapy appears to be safe, effective for some pancreatic cancer patients

Zona Plus isometric handgrip device now available in Canada for patients with high blood pressure

Johns Hopkins researchers identify new therapy to treat lung cancer

Magstim Rapid2 Therapy System receives FDA clearance for treatment of drug resistant MDD

Similar diabetic macular oedema outcomes with deferred vs prompt laser therapy

MedVantx launches MedStart Formulary Connect program for health systems and ACOs

DNAtrix signs agreement to utilize Alcyone's MEMS platform for direct drug delivery into glioblastoma

Vitamin E helps build strong muscles

Current menopausal hormone therapy users at increased risk of experiencing GI bleeding

Naldemedine shows promise in treating OIC in patients with chronic non-cancer pain.

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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