Apoptosis News and Research

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Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

Study links a novel protein pathway to the aggressive progression of breast cancer

Cytogen Corporation today announced the publication of a study linking a novel protein pathway to the aggressive progression of breast cancer.

24 Nov 2004

Acetaminophen shows positive cardioprotective effects In heart attack, arrhythmia

Long an under-studied yet widely-used over-the-counter medication, acetaminophen over the last few years is becoming recognized for a range of potential therapeutic uses beyond headache and pain.

16 Nov 2004

Enzyme that normally alters the activity of other protein molecules in cells may also help prevent cancer

The enzyme is known as PTPRO (for “protein tyrosine phosphatase receptor-type O”). When the gene responsible for producing PTPRO is silenced, as can happen in lung cancer, for example, the amount of the enzyme drops, allowing the cells to grow when they shouldn’t.

11 Nov 2004

Researchers have developed a new algorithm that can lead to more accurate detection of cancer genes

Researchers at New York University's Courant Institute of Mathematical Sciences have developed a new algorithm that can lead to more accurate detection of cancer genes than previous versions.

8 Nov 2004

Autophagy may even provide a clue to the mythical fountain of youth

The cells of higher organisms have an internal mechanism for chewing up and recycling parts of themselves, particularly in times of stress, like starvation and disease. But nobody is quite sure yet whether this recently discovered process protects cells, or causes damage.

5 Nov 2004

Celebrex may one day be used to prevent and even treat breast tumors

The anti-inflammatory drug Celebrex, or celecoxib, reduces tumor mass by encouraging cell death and discouraging both cell proliferation and the sprouting of new blood vessels that feed growing tumors, according to a study reported in the November issue of Molecular Cancer Research.

5 Nov 2004

FDA fast tracks investigational anti-cancer drug, phenoxodiol

Marshall Edwards today announced that the U.S. Food and Drug Administration (FDA) has granted the investigational anti-cancer drug, phenoxodiol, Fast Track status for its intended use in patients with recurrent ovarian cancer.

4 Nov 2004

Maxim Pharmaceuticals to withdraw NDA for advanced malignant melanoma

Maxim Pharmaceuticals has announced that based upon the negative outcome of it's confirmatory Phase 3 clinical trial (M0104) studying Ceplene(TM) (histamine dihydrochloride) in combination with Interleukin-2 (IL-2) in advanced malignant melanoma patients with liver metastases, it plans to close the treatment protocol approved by the FDA earlier this year.

2 Nov 2004

Common antibacterial and antifungal ingredient used in tooth paste may protect against skin cancer

According to new studies, sanguinarine was shown to enhance production of proteins that induce cell death, or apoptosis, in cells damaged by ultraviolet-B (UVB) radiation.

21 Oct 2004

Cyclopamine, derived from the corn lily may treat and prevent basal cell carcinoma

Researchers at the University of Texas Medical Branch at Galveston (UTMB) have demonstrated in laboratory animals that a compound derived from a common plant can be used to treat and prevent the most widespread form of cancer in people

18 Oct 2004

Researchers stimulate the body to repair tissue damaged by peripheral arterial obstructive disease

Duke University Medical Center researchers have shown that they can stimulate the body to produce its own naturally occurring growth factors to promote blood vessel growth into tissue damaged by peripheral arterial obstructive disease (PAOD).

13 Oct 2004

Lithium can protect the brain cells involved in learning and memory from radiation damage

Patients who undergo radiation for treatment of brain tumors may survive their cancer only to have lasting memory and learning deficiencies, the impact of which can be particularly devastating for children.

10 Oct 2004

FDA fast tracks Genaera's drug for the treatment of wet age-related macular degeneration

Genaera Corporation has announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to squalamine, an intravenously administered, first in class, small molecule anti-angiogenic drug for the treatment of "wet" age-related macular degeneration (AMD).

4 Oct 2004

Novel compound that resembles vitamin E halves the size of tumors and the ability of cancer to spread

By studying cancer in mice, researchers at The University of Texas at Austin have gained preliminary evidence that a novel compound that resembles vitamin E halves the size of tumors and the ability of cancer to spread to other body sites.

30 Sep 2004

Researchers show gossypol – a drug refined from cottonseed oil is a cancer treatment booster

New research has opened up the prospect that gossypol – a drug refined from cottonseed oil and previously tried and abandoned as a male contraceptive – could boost the effectiveness of treatment for prostate tumours and possibly other common cancers as well.

30 Sep 2004

Phase II trials of the first second-generation antisense cancer drug to be used in patients soon to be underway

Phase II trials of the first second-generation antisense cancer drug to be used in patients are soon to be underway in the wake of a successful Phase I study, which has demonstrated that the new drug blocks its target gene in exactly the way it is designed to do.

28 Sep 2004

Apoptosis News and Research

Study links a novel protein pathway to the aggressive progression of breast cancer

Acetaminophen shows positive cardioprotective effects In heart attack, arrhythmia

Enzyme that normally alters the activity of other protein molecules in cells may also help prevent cancer

Researchers have developed a new algorithm that can lead to more accurate detection of cancer genes

Autophagy may even provide a clue to the mythical fountain of youth

Celebrex may one day be used to prevent and even treat breast tumors

FDA fast tracks investigational anti-cancer drug, phenoxodiol

Maxim Pharmaceuticals to withdraw NDA for advanced malignant melanoma

Common antibacterial and antifungal ingredient used in tooth paste may protect against skin cancer

Cyclopamine, derived from the corn lily may treat and prevent basal cell carcinoma

Researchers stimulate the body to repair tissue damaged by peripheral arterial obstructive disease

Lithium can protect the brain cells involved in learning and memory from radiation damage

FDA fast tracks Genaera's drug for the treatment of wet age-related macular degeneration

Novel compound that resembles vitamin E halves the size of tumors and the ability of cancer to spread

Researchers show gossypol – a drug refined from cottonseed oil is a cancer treatment booster

Phase II trials of the first second-generation antisense cancer drug to be used in patients soon to be underway

Arsenic trioxide - invented as a treatment for a rare type of leukaemia

Four or more glasses of red wine per week may reduce risk of prostate cancer by 50 percent

New link in the growth of Ewing’s sarcoma

Scientists have corrected a flaw in cancer cells that lets them evade the normal cell-death process

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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