Membrane News and Research

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Vaccines and drugs must be adapted to combat emerging SARS-CoV-2 variants, says study

A new review of the emerging variants of concern (VOCs) of the SARS-CoV-2, which has caused the COVID-19 pandemic, shows that there is a major need to constantly re-evaluate the utility of existing therapeutics and vaccines against the virus and to develop new ones.

28 Jun 2021

Why SARS-CoV-2 delta variant is more infectious

German experts recently explained why the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant is more infectious and pathogenic than its ancestor. By conducting a series of in vitro experiments, they have revealed that increased ability to induce cell-to-cell fusion (syncytia) and reduced susceptibility to vaccine and infection-induced antibodies make the delta variant more infectious than previously circulating variants. The study is currently available on the bioRxiv* preprint server.

28 Jun 2021

Researchers determine molecular structure of bacterial protein complex critical for tuberculosis

Tuberculosis is one of the top ten causes of death worldwide, infecting about one-quarter of the world's population. Although it is treatable, the rise of multidrug-resistant tuberculosis poses a major threat to global health security, and has been declared by the World Health Organization as a global health emergency.

25 Jun 2021

Fundamental insights on key protein can help strengthen plants against environmental stress

An international study led by Helmholtz Zentrum München has revealed the structure of a membrane-remodeling protein that builds and maintains photosynthetic membranes. These fundamental insights lay the groundwork for bioengineering efforts to strengthen plants against environmental stress, helping to sustaining human food supply and fight against climate change.

25 Jun 2021

Surprising similarities found in membrane proteins of bacteria and humans

The cells of simple organisms, such as bacteria, as well as human cells are surrounded by a membrane, which fulfills various tasks including protecting the cell from stress.

24 Jun 2021

Scientists identify new virulence mechanism for a surface protein on pneumonia-causing bacteria

A bout with flu virus can be hard, but when Streptococcus pneumonia enters the mix, it can turn deadly.

24 Jun 2021

SARS-CoV-2 causes ER-stress-activated unfolded protein response leading to cell death

A new study describes the varying ways in which the virus co-opts the machinery of the host cell following infection to evade or modulate the host immune response, alter the pattern of translation of viral proteins, and the release of new viral particles.

24 Jun 2021

Study finds no evidence for remdesivir's benefit in severe COVID-19 patients

A new analysis of current data indicates that remdesivir does not show efficacy in regulating the severity of the illness.

23 Jun 2021

Researchers study COVID-19 immune dysfunction in relation to phosphatidylserine

Often patients suffering from COVID-19 (coronavirus disease) show striking immune dysregulation - causing increased morbidity and mortality. Mechanisms for adaptive immune disturbance, lymphopenia, and thromboinflammation in COVID-19 are still poorly understood.

23 Jun 2021

Researchers review the origins of SARS-CoV-2 and present treatment methods

A million more questions arise for every answer we have against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Where did it come from? And will it ever go away? A recent article published in Frontiers in Cellular and Infection Microbiology reviews what scientists currently know about the origin, SARS-CoV-2 structure, and potential treatments against this new virus.

23 Jun 2021

Repligen Corporation Announces Agreement to Acquire Polymem S.A.

Repligen Corporation today announced that it has entered into an agreement to acquire Toulouse, France-based Polymem S.A., a leading industrial expert.

23 Jun 2021

Study determines the mechanism behind respiratory inflammation and finds effective treatment

Applied Biological Laboratories (Applied Bio), a biopharmaceutical company focused on the respiratory disease market, announced that its study published online in Immunology, Inflammation and Disease was able to determine the mechanism behind respiratory inflammation and treat it effectively with Biovanta(TM), a 100% naturally derived, over-the-counter (OTC) drug for cold, cough and sore throat.

22 Jun 2021

Upper airway model derived from iPSCs paves the way for broader studies of viral lung infections

A team led by researchers at Newcastle University, UK has successfully created a model of the cells found in the lungs that can be used to replicate how COVID-19 infects the airways.

21 Jun 2021

University of Louisville receives NIH funding to support research into liver-related illness

The University of Louisville Hepatobiology and Toxicology Center of Biomedical Research Excellence has received $11.3 million in funding from the National Institutes of Health to support its research into liver-related illness for an additional five years.

21 Jun 2021

Targeting lung inflammation with cell membrane-based dexamethasone nanodelivery platform

Recently, researchers discuss their development of cell membrane-based nanoparticles that successfully delivered dexamethasone directly to inflamed lung cells.

21 Jun 2021

Gasdermin D plays a key role in the maturation and release of IL-1α

Interluekin-1α (IL-1α) is an important part of the immune response, but until now it has been unclear how this molecule is processed from its precursor, pro-IL-1α, and exits the cell during inflammasome activation.

21 Jun 2021

Scientists develop low-cost lab-on-paper device for rapid and accurate detection of SARS-CoV-2

A team of scientists from the University of Connecticut, USA, has developed a low-cost lab-on-paper technology to rapidly and easily detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The work has recently been published in a Royal Society of Chemistry’s Lab on a Chip journal.

18 Jun 2021

Fighting the good fight –a new protein found in red blood cells linked to limiting cognitive decline

A new study shows that depleting mouse blood of the protein ADORA2B led to faster declines in memory, and increased brain inflammation.

18 Jun 2021

Study examines SARS-CoV-2 replication in cells using super-resolution microscopy

Despite tremendous efforts by the global scientific community to curb the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), by developing more efficient testing protocols, therapies, and vaccines at a rapid pace, relatively little is known about the dynamics of SARS-CoV-2 replication within cells.

18 Jun 2021

Nanodecoys made from human lung spheroid cells can neutralize SARS-CoV-2

Nanodecoys made from human lung spheroid cells (LSCs) can bind to and neutralize SARS-CoV-2, promoting viral clearance and reducing lung injury in a macaque model of COVID-19.

18 Jun 2021

Membrane News and Research

Vaccines and drugs must be adapted to combat emerging SARS-CoV-2 variants, says study

Why SARS-CoV-2 delta variant is more infectious

Researchers determine molecular structure of bacterial protein complex critical for tuberculosis

Fundamental insights on key protein can help strengthen plants against environmental stress

Surprising similarities found in membrane proteins of bacteria and humans

Scientists identify new virulence mechanism for a surface protein on pneumonia-causing bacteria

SARS-CoV-2 causes ER-stress-activated unfolded protein response leading to cell death

Study finds no evidence for remdesivir's benefit in severe COVID-19 patients

Researchers study COVID-19 immune dysfunction in relation to phosphatidylserine

Researchers review the origins of SARS-CoV-2 and present treatment methods

Repligen Corporation Announces Agreement to Acquire Polymem S.A.

Study determines the mechanism behind respiratory inflammation and finds effective treatment

Upper airway model derived from iPSCs paves the way for broader studies of viral lung infections

University of Louisville receives NIH funding to support research into liver-related illness

Targeting lung inflammation with cell membrane-based dexamethasone nanodelivery platform

Gasdermin D plays a key role in the maturation and release of IL-1α

Scientists develop low-cost lab-on-paper device for rapid and accurate detection of SARS-CoV-2

Fighting the good fight –a new protein found in red blood cells linked to limiting cognitive decline

Study examines SARS-CoV-2 replication in cells using super-resolution microscopy

Nanodecoys made from human lung spheroid cells can neutralize SARS-CoV-2

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

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