Proliferation News and Research

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Scientists discover new target in the treatment of pulmonary hypertension

In a recent study, scientists found that eliminating the FoxM1 gene could improve outcomes for patients with pulmonary hypertension.

1 May 2018

Researchers recommend anti-cancer immunotherapies for treatment of thyroid cancer

University of Colorado Cancer Center researchers recently completed the largest-ever study of thyroid cancer genetics, mining the data of 583 patient samples of advanced differentiated thyroid cancer and 196 anaplastic thyroid cancers.

27 Apr 2018

Researchers uncover the mystery of B cell receptors

When a pathogen evades or overcomes our innate immune defenses, the adaptive immune system kicks into action. There are two types of adaptive immune responses: cell-mediated immunity mediated by T cells and humoral immunity mediated by antibodies produced by B cells.

27 Apr 2018

Scientists discover potential therapeutic target for devastating premature aging disease

Scientists from the University of Cambridge have identified a potential therapeutic target in the devastating genetic disease Hutchinson-Gilford Progeria Syndrome (HGPS), which is characterized by premature aging.

27 Apr 2018

Specific type of RNA editing plays key role in protein variation in cancer cells, shows research

A multi-center study led by The University of Texas MD Anderson Cancer Center has shed light on why proteins, the seedlings that serve as the incubator for many cancers, can vary from cancer to cancer and even patient to patient, a discovery that adds to a growing base of knowledge important for developing more effective precision therapies.

27 Apr 2018

Research leads to new potential treatment for Hereditary Hemorrhagic Telangiectasia

The work of researchers Francesc Viñals and Mariona Graupera at the Bellvitge Biomedical Research Institute - Catalan Institute of Oncology - University of Barcelona, together with Dr. Antoni Riera-Mestre, has led to a new potential treatment for Hereditary Hemorrhagic Telangiectasia or Rendu-Osler Syndrome, a rare disease that affects blood vessels and had no described treatment.

26 Apr 2018

Researchers target telomerase for killing NRAS-mutant melanoma cells

Targeting telomerase was effective at killing NRAS-mutant melanoma cells, and the impact was further enhanced when the strategy was paired with an inhibitor of mitochondrial function, according to study results by The Wistar Institute published in Oncogene.

26 Apr 2018

Study explains how colon cancer cells spread to the liver

Colorectal cancer is the third most common cancer worldwide and the third-leading cause of cancer-related deaths. The main cause of death in patients with colorectal cancer is liver metastasis, with nearly 70% of patients eventually developing a liver tumor.

25 Apr 2018

Hippo pathway plays essential role in embryonic development of the mouse heart

Using a technology that provides a 'high-resolution view' of the status of individual cells, a team of researchers has gained new insights into the embryonic development of the mouse heart.

24 Apr 2018

GPs must embrace digital technologies to make healthcare access easier for patients

Few now question that harnessing technology and digital innovation is critical to the future of the NHS. The model of booking a face-to-face appointment with your GP has barely changed since 1948 but the pressure on patients and doctors has changed beyond recognition.

24 Apr 2018

New initiative launched to support goals of Human Cell Atlas

Uri Laserson, PhD, Assistant Professor in the Department of Genetics and Genomics Sciences at the Icahn School of Medicine at Mount Sinai, and collaborators have been awarded one of 85 grants announced today from the Chan Zuckerberg Initiative DAF (CZI), an advised fund of Silicon Valley Community Foundation.

20 Apr 2018

New insight may allow researchers to design drugs that improve immune responses to vaccines

Memory T cells are a critical element of our immune system's historical archive. To prevent repeat infections, these cells retain a record of germs they've fought before.

19 Apr 2018

Researchers use 'top-down proteomics' strategy to get new insights into cancer

When a RAS gene operates normally, it acts as an on/off switch for cell signaling to control cell proliferation. But when the gene mutates, the switch jams into the "on" position, allowing cells to proliferate uncontrollably.

18 Apr 2018

New 'lymphoma micro-reactor' device targets chemo-resistant tumors

Non-Hodgkin lymphoma, a cancer that is diagnosed in the U.S. more than 70,000 times annually, arises from overly proliferating immune cells within the body's lymph nodes, which are connected to a network of lymph vessels through which lymphatic fluid flows.

12 Apr 2018

Targeting metabolism of key nutrients could be effective in treating squamous cell carcinoma

Researchers from UCLA and Long Beach Memorial Medical Center have found that two targeted therapies could be more effective if used in combination to treat squamous cell carcinomas of the lung.

12 Apr 2018

Transcription factor Sp7 found to play key role in tooth development

Amjad Javed, Ph.D., and University of Alabama at Birmingham colleagues have found a key role in tooth development for the transcription factor Specificity protein 7, or Sp7.

11 Apr 2018

Researchers discover key enzyme driving breast cancer

Looking to identify new strategies to prevent breast cancer recurrence, a research team led by Subhamoy Dasgupta, PhD, Assistant Professor of Oncology in the Department of Cell Stress Biology at Roswell Park Comprehensive Cancer Center, has identified two key proteins involved in glucose metabolism that could be targeted to prevent breast cancer metastasis and recurrence. The team's findings were published today in the journal Nature.

11 Apr 2018

Finding new drug target for common form of lung cancer

Research by Rutgers Cancer Institute of New Jersey investigators has identified novel functions of the superoxide dismutase 1 (SOD1) enzyme providing support that it could serve as a therapeutic target in the most common type of lung cancer.

10 Apr 2018

Vascular stabilization biomarker helps optimize timing of anticancer therapies

Angiogenesis, the formation of new blood vessels, is essential for tumor growth. A new study reported in The American Journal of Pathology describes a vascular stabilization biomarker that can visualize blood vessel activity, thus optimizing the timing of anticancer therapies including anti-angiogenics.

9 Apr 2018

Researchers discover a new molecular cause for aggressive leukemia in children

Around 600 children under the age of 15 are diagnosed with leukemia each year in Germany. The effects are especially dramatic if this severe illness develops at birth or shortly afterwards.

4 Apr 2018

Proliferation News and Research

Scientists discover new target in the treatment of pulmonary hypertension

Researchers recommend anti-cancer immunotherapies for treatment of thyroid cancer

Researchers uncover the mystery of B cell receptors

Scientists discover potential therapeutic target for devastating premature aging disease

Specific type of RNA editing plays key role in protein variation in cancer cells, shows research

Research leads to new potential treatment for Hereditary Hemorrhagic Telangiectasia

Researchers target telomerase for killing NRAS-mutant melanoma cells

Study explains how colon cancer cells spread to the liver

Hippo pathway plays essential role in embryonic development of the mouse heart

GPs must embrace digital technologies to make healthcare access easier for patients

New initiative launched to support goals of Human Cell Atlas

New insight may allow researchers to design drugs that improve immune responses to vaccines

Researchers use 'top-down proteomics' strategy to get new insights into cancer

New 'lymphoma micro-reactor' device targets chemo-resistant tumors

Targeting metabolism of key nutrients could be effective in treating squamous cell carcinoma

Transcription factor Sp7 found to play key role in tooth development

Researchers discover key enzyme driving breast cancer

Finding new drug target for common form of lung cancer

Vascular stabilization biomarker helps optimize timing of anticancer therapies

Researchers discover a new molecular cause for aggressive leukemia in children

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