immunity News and Research

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Researchers use a comparative study to model RSV prevention in children

Using computational modeling, a new paper compares the benefit of maternal vaccines versus the administration of respiratory syncytial virus (RSV)-specific monoclonal antibody (mAb) therapy against RSV.

28 Nov 2022

When malpractice occurs at community health centers, taxpayers pay

Silvia Garcia's 14-year-old son was left permanently disabled and in a wheelchair after a community health center doctor in New Mexico failed to diagnose his appendicitis despite his complaint of severe stomach pain.

28 Nov 2022

Are nasal-spray vaccines the solution to respiratory infectious diseases?

A recent study published in the journal Trends in Molecular Medicine reviewed the current efforts in developing nasal vaccines, delivery systems, and clinical applications for preventing respiratory illnesses.

28 Nov 2022

Memory B and T cells responses differ when induced by SARS-CoV-2 infections or booster vaccinations

In a recent study published in The Journal of Immunology, a team of researchers from Japan examined the memory B and T cell responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein after the booster dose of the coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccine BNT162b2.

27 Nov 2022

Nanoparticles displaying SARS-CoV-1 and SARS-CoV-2 spikes induce broad antibody responses in animal model

A recent study published in the journal iScience reported that nanoparticles (NPs) co-displaying spike proteins from different sarbecoviruses improve the breadth of neutralizing responses.

27 Nov 2022

Study finds increased risk of severe asthma attacks after relaxation of Covid-19 restrictions

Adults with asthma had, at one point, an approximately doubled risk of a severe asthma attack after Covid-19 restrictions were relaxed in the UK, according to new research from Queen Mary University of London, funded by Barts Charity.

25 Nov 2022

Multivalent mRNA-based vaccine may serve as a preventative measure against future flu pandemics

An experimental mRNA-based vaccine against all 20 known subtypes of influenza virus provided broad protection from otherwise lethal flu strains in initial tests, and thus might serve one day as a general preventative measure against future flu pandemics, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

25 Nov 2022

BW.1- a new Omicron subvariant that escapes immunity

Researchers reports the presence of mutations that aid in immune escape in the BW.1 Omicron subvariant.

25 Nov 2022

All eligible people urged to get vaccinated due to higher rates of flu cases than usual

All those eligible for the flu vaccine have been urged to come forward as cases rise to levels not seen since before the pandemic.

24 Nov 2022

Voluntary 'mass testing' associated with 25% reduction in covid-19 related hospitalizations

The first ever voluntary 'mass testing' pilot for people without covid symptoms was associated with an overall 25% reduction in covid-19 related hospital admissions, including an initial 43% reduction with military assistance, finds a study published by The BMJ today.

24 Nov 2022

Do previously infected individuals still benefit from vaccination against COVID-19?

Researchers determined the vaccine effectiveness (VE) of the primary coronavirus disease 2019 (COVID-19) vaccination series.

24 Nov 2022

The relationship between neutralization levels and observed efficacies against asymptomatic and symptomatic infection of ten COVID-19 vaccines

Researchers determined whether neutralizing antibody levels were predictive of the efficacy of fractional vaccine doses against SARS-CoV-2 infection.

24 Nov 2022

Duke researchers find human DNA sequence divergence after split from common ancestor of chimpanzees

A team of Duke researchers has identified a group of human DNA sequences driving changes in brain development, digestion and immunity that seem to have evolved rapidly after our family line split from that of the chimpanzees, but before we split with the Neanderthals.

24 Nov 2022

Single-cell transcriptome analysis provides insights into bat immunity

In a world first, scientists at Duke-NUS Medical School and colleagues in Singapore have sequenced the response to viral infection in colony-bred cave nectar bats (Eonycteris spelaea) at single-cell resolution.

24 Nov 2022

Study demonstrates that Paxlovid protects severe COVID-19–associated outcomes among persons for whom it is recommended

Researchers assessed the association between receiving a prescription for Paxlovid and COVID-19-related hospitalization in the ensuing 30 days.

24 Nov 2022

COVID-19 vaccination provides 60% to 94% protection against reinfection

Individuals previously infected with SARS-CoV-2, the virus that causes COVID-19, still benefit from vaccination, gaining 60% to 94% protection against reinfection, depending on the variant.

23 Nov 2022

CAR T therapy extends its reach beyond oncology

Engineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can do to fight blood cancers.

23 Nov 2022

Bivalent mRNA vaccines could enhance protective efficacy against COVID-19

A new study presents evidence suggestive of restored or increased efficacy from changing the formulation of COVID-19 vaccines to a bivalent one.

23 Nov 2022

Study suggests the behavior of an emergent SARS-CoV-2 variant may be sensitive to the immunologic and demographic context of its location

Researchers characterized the heterogeneity in the speed, magnitude, and timing of 13 SARS-CoV-2 variant transitions/waves.

23 Nov 2022

How did population immunity against SARS-CoV-2 infection and subsequent severe disease change between December 2021 and November 2022?

Researchers explored the alterations in population immunity against SARS-CoV-2 Omicron variant infection and severe disease.

23 Nov 2022

immunity News and Research

Researchers use a comparative study to model RSV prevention in children

When malpractice occurs at community health centers, taxpayers pay

Are nasal-spray vaccines the solution to respiratory infectious diseases?

Memory B and T cells responses differ when induced by SARS-CoV-2 infections or booster vaccinations

Nanoparticles displaying SARS-CoV-1 and SARS-CoV-2 spikes induce broad antibody responses in animal model

Study finds increased risk of severe asthma attacks after relaxation of Covid-19 restrictions

Multivalent mRNA-based vaccine may serve as a preventative measure against future flu pandemics

BW.1- a new Omicron subvariant that escapes immunity

All eligible people urged to get vaccinated due to higher rates of flu cases than usual

Voluntary 'mass testing' associated with 25% reduction in covid-19 related hospitalizations

Do previously infected individuals still benefit from vaccination against COVID-19?

The relationship between neutralization levels and observed efficacies against asymptomatic and symptomatic infection of ten COVID-19 vaccines

Duke researchers find human DNA sequence divergence after split from common ancestor of chimpanzees

Single-cell transcriptome analysis provides insights into bat immunity

Study demonstrates that Paxlovid protects severe COVID-19–associated outcomes among persons for whom it is recommended

COVID-19 vaccination provides 60% to 94% protection against reinfection

CAR T therapy extends its reach beyond oncology

Bivalent mRNA vaccines could enhance protective efficacy against COVID-19

Study suggests the behavior of an emergent SARS-CoV-2 variant may be sensitive to the immunologic and demographic context of its location

How did population immunity against SARS-CoV-2 infection and subsequent severe disease change between December 2021 and November 2022?

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