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Antigen-loaded porous silicon microparticles can boost effectiveness of breast cancer vaccines

The effectiveness of cancer vaccines could be dramatically boosted by first loading the cancer antigens into silicon microparticles, report scientists from Houston Methodist and two other institutions in an upcoming Cell Reports (early online).

6 May 2015

Researchers identify gene variant that affects onset of Huntington's disease

Researchers at Sweden's Karolinska Institutet and the University of British Columbia, Canada, have identified a gene variant that influences whether Huntington's disease breaks out earlier or later than expected. The findings, which are published in the scientific journal Nature Neuroscience, can contribute to improved diagnosis and disease-modifying therapies.

5 May 2015

T cell expansion technology: an interview with Alexander Malykhin, CVPF, University of Pennsylvania

T cells are taken from the patient’s blood and then modified using lentivirus, adenovirus or RNA electroporation.

From Beckman Coulter Life Sciences - Flow Cytometry 5 May 2015

Scientists grow miniature human myelomas in shell-less chicken eggs to study multiple myeloma

Multiple myeloma is an incurable cancer of the bone marrow. To date, no screening systems have been available to examine the effects of new drugs in a 3D environment. Researchers on the EU project OPTATIO might now fill this gap. They succeeded in growing miniature human myelomas in shell-less chicken eggs in order to screen new marine compounds for anti-myeloma activity.

5 May 2015

St. Jude scientists develop new computer tool to find DNA duplications and deletions in tumors

St. Jude Children's Research Hospital scientists have developed a significantly better computer tool for finding genetic alterations that play an important role in many cancers but were difficult to identify with whole-genome sequencing.

5 May 2015

Moderate exercise on a regular basis may improve cancer treatments

Kansas State University kinesiology research offers encouraging information for cancer patients: A brisk walk or a slow jog on a regular basis may be the key to improved cancer treatments.

5 May 2015

New understanding of how Huntington's disease gene works

Huntington's disease is caused by a mutation in the Huntington's disease gene, but it has long been a mystery why some people with the exact same mutation get the disease more severely and earlier than others. A closer look at the DNA around the Huntington's disease (HD) gene offers researchers a new understanding of how the gene is controlled and how this affects the disease.

5 May 2015

Findings provide glimmer of hope for treating diffuse intrinsic pontine gliomas

Using brain tumor samples collected from children in the United States and Europe, an international team of scientists found that the drug panobinostat and similar gene regulating drugs may be effective at treating diffuse intrinsic pontine gliomas (DIPG), an aggressive and lethal form of pediatric cancer.

5 May 2015

Study could provide new approaches to treating meniscal injuries

Within the knee, two specialized, C-shaped pads of tissue called menisci perform many functions that are critical to knee-joint health. The menisci, best known as the shock absorbers in the knee, help disperse pressure, reduce friction and nourish the knee.

5 May 2015

AIDS patients at increased risk of developing intermediate-stage AMD

Patients with acquired immunodeficiency syndrome (AIDS) have a four-fold increase in their risk of developing intermediate-stage age-related macular degeneration (AMD) compared to people of the same age who are not infected with HIV, according to results from the Longitudinal Study of the Ocular Complications of AIDS (LSOCA) presented today at the 2015 ARVO Annual Meeting in Denver, CO.

5 May 2015

IQWiG finds minor added benefit of dulaglutide in combination with short-acting insulin for type 2 diabetes

Since 2014 dulaglutide has been approved alone or in combination with other drugs for the treatment of adults with type 2 diabetes. The German Institute for Quality and Efficiency in Health Care examined in a dossier assessment whether this new drug offers an added benefit over the appropriate comparator therapies.

5 May 2015

Researchers identify multiple types of resistance to new targeted lung cancer drug

After identifying three different types of resistance to a promising investigational lung cancer drug in a phase 1 trial, a team of researchers led by Dana-Farber Cancer Institute scientists say new targeted inhibitors and combinations are urgently needed to stay ahead of tumors' constant and varied molecular shape-shifting.

5 May 2015

Chickenpox virus can cause strokes in patients with compromised immune systems

Patients infected with human immunodeficiency virus (HIV) can, in rare cases, experience bleeding on the brain that causes a type of stroke called intracerebral hemorrhage.

5 May 2015

Study shows how pharmacies may play important role in reducing asthma-related illness

A new study shows how pharmacies might collaborate with physicians and families to reduce asthma-related illness.

4 May 2015

No evidence for cancer risk with growth hormone therapy

There is no evidence that growth hormone (GH) therapy increases the likelihood of neoplasms in children with no additional risk factors, says the Pediatric Endocrine Society Drug and Therapeutics Committee.

1 May 2015

Long-term histrelin implant shows promise for central precocious puberty

Long-term subcutaneous histrelin implant therapy is a viable option for patients with central precocious puberty who require continuous gonadotropin-releasing hormone analogue therapy, say researchers.

1 May 2015

Keynote 24 study explores investigational approach to treating lung cancer

Lung cancer impacts the lives of millions of people worldwide. In nearly 40 percent of people diagnosed with lung cancer, it has metastasized, or spread to other areas of the body, making it difficult to treat. Immunotherapy is a type of therapy that uses the body's own immune system to help fight cancer. Immunotherapy may help the body's immune system target cancer cells.

30 Apr 2015

ResMed launches Lumis series of noninvasive ventilation devices to manage respiratory stability of patients

ResMed today announced its Lumis series of noninvasive ventilation devices that combine personalized, simplified therapy with powerful wireless connected care capabilities. The Lumis series builds upon ResMed's legacy of innovation as a new option for patients with respiratory challenges who are not dependent on continuous ventilation.

From ResMed Corp 30 Apr 2015

HeartWare International's revenue increases 5% to $70.0 million in first quarter 2015

HeartWare International, Inc., a leading innovator of less invasive, miniaturized circulatory support technologies that are revolutionizing the treatment of advanced heart failure, today announced revenue of $70.0 million for the first quarter ended March 31, 2015, a five percent increase compared to $66.5 million in revenue for the same period of 2014.

30 Apr 2015

Neurocrine reports net loss of $1.2 million for first quarter 2015

Neurocrine Biosciences, Inc. today announced its financial results for the quarter ended March 31, 2015. For the first quarter of 2015, the Company reported a net loss of $1.2 million, or $0.01 loss per share, compared to a net loss of $11.8 million, or $0.17 loss per share, for the same period in 2014.

30 Apr 2015

Therapy News and Research

Antigen-loaded porous silicon microparticles can boost effectiveness of breast cancer vaccines

Researchers identify gene variant that affects onset of Huntington's disease

T cell expansion technology: an interview with Alexander Malykhin, CVPF, University of Pennsylvania

Scientists grow miniature human myelomas in shell-less chicken eggs to study multiple myeloma

St. Jude scientists develop new computer tool to find DNA duplications and deletions in tumors

Moderate exercise on a regular basis may improve cancer treatments

New understanding of how Huntington's disease gene works

Findings provide glimmer of hope for treating diffuse intrinsic pontine gliomas

Study could provide new approaches to treating meniscal injuries

AIDS patients at increased risk of developing intermediate-stage AMD

IQWiG finds minor added benefit of dulaglutide in combination with short-acting insulin for type 2 diabetes

Researchers identify multiple types of resistance to new targeted lung cancer drug

Chickenpox virus can cause strokes in patients with compromised immune systems

Study shows how pharmacies may play important role in reducing asthma-related illness

No evidence for cancer risk with growth hormone therapy

Long-term histrelin implant shows promise for central precocious puberty

Keynote 24 study explores investigational approach to treating lung cancer

ResMed launches Lumis series of noninvasive ventilation devices to manage respiratory stability of patients

HeartWare International's revenue increases 5% to $70.0 million in first quarter 2015

Neurocrine reports net loss of $1.2 million for first quarter 2015

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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