Therapy News and Research

RSS

OncoGenex provides update on Phase 3 ENSPIRIT trial evaluating custirsen for treatment of NSCLC

OncoGenex Pharmaceuticals, Inc. announced today it has filed an amendment with the U.S. Food and Drug Administration, as well as initiated filing with regulatory agencies in other countries, to amend the statistical design and analysis plan of its pivotal, international Phase 3 ENSPIRIT trial evaluating custirsen in the treatment of non-small cell lung cancer (NSCLC).

30 Apr 2015

Novel combination therapy shows promise in mouse models of advanced prostate cancer

Chemotherapy can be very effective against small prostate tumors. Larger prostate tumors, however, accumulate cells that suppress the body's immune response, allowing the cancer to grow despite treatment.

30 Apr 2015

Study finds that gene therapy can clip out genetic material associated with heart failure

Gene therapy can clip out genetic material linked to heart failure and replace it with the normal gene in human cardiac cells, according to a study led by researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai.

30 Apr 2015

Cytokine GM-CSF likely plays important role in MS

Multiple sclerosis (MS) is caused by immune cells that activate a cascade of chemicals in the brain, attacking and degrading the insulation that keeps neuronal signals moving. These chemicals, called cytokines, drive the inflammation in the brain, attracting more immune cells, and causing the debilitating disease marked by loss of neurological function.

30 Apr 2015

Adult survivors of preterm births at higher risk of developing COPD

Adult survivors of preterm births may have a lung capacity that resembles the healthy elderly or casual smokers by the time they reach their early 20s, according to a University of Oregon study.

30 Apr 2015

Patients with traumatic brain injuries need effective cognitive neuroscience-based therapies

Patients with traumatic brain injuries are not benefiting from recent advances in cognitive neuroscience research - and they should be, scientists report in a special issue of Current Opinion in Behavioral Sciences.

30 Apr 2015

CANCER-ID consortium aims to set up standard procedures for clinical validation of blood-based biomarkers

Blood-based biomarkers such as circulating tumor cells (CTCs), circulating free DNA (cfDNA), circulating tumor DNA (ctDNA) and microRNAs (miRNAs) are potential indicators for the tumor burden of patients living with cancer.

30 Apr 2015

Better interventions needed to improve outcomes in young breast cancer patients

Breast cancer that occurs in young women is likely to be more aggressive and to require more intensive types of therapy with increased risk of long-term treatment-related toxicities. The unique and significant challenges and psychosocial concerns that women under 40 years of age with breast cancer face are discussed in a special article published in Journal of Adolescent and Young Adult Oncology, a multidisciplinary peer-reviewed publication from, Mary Ann Liebert, Inc., publishers.

30 Apr 2015

TDF switch effective in Asian chronic HBV patients

Switching therapy to tenofovir disoproxil fumarate is effective in treatment-resistant chronic hepatitis B, show results from a cohort of Asian patients.

29 Apr 2015

Kidney damage unlikely with TDF monotherapy in chronic HBV patients

In patients with chronic hepatitis B virus infection, treatment with tenofovir disoproxil fumarate does not significantly increase the risk of developing renal dysfunction compared with entecavir treatment, a US team reports.

29 Apr 2015

Patients with adefovir-resistant HBV benefit from TDF monotherapy

Tenofovir disoproxil fumarate alone elicits a response comparable to that of TDF plus entecavir in heavily pretreated patients with chronic hepatitis B virus infection resistant to adefovir dipivoxil, research suggests.

29 Apr 2015

University of St. Augustine plans to bring Doctor of Physical Therapy program to Miami

The University of St. Augustine for Health Sciences plans to bring its Doctor of Physical Therapy program to Miami in fall 2015, pending accreditation and other regulatory approvals. The university, which has been a part of north Florida for more than 20 years, will open its new campus near the Dolphin Mall.

29 Apr 2015

Sangamo BioSciences to present data on ZFP Therapeutic platform at ASGCT meeting

Sangamo BioSciences, Inc. announced that data from clinical, preclinical and research-stage programs focused on the development of ZFP Therapeutics will be presented at the 18th Annual Meeting of the American Society of Gene and Cell Therapy

29 Apr 2015

UI orthopedics researchers working on injectable, bioactive gel that can repair cartilage damage

Knee injuries are the bane of athletes everywhere, from professionals and college stars to weekend warriors. Current surgical options for repairing damaged cartilage caused by knee injuries are costly, can have complications, and often are not very effective in the long run. Even after surgery, cartilage degeneration can progress leading to painful arthritis.

29 Apr 2015

Scientists identify new way to predict disease outcomes in people with rheumatoid arthritis

Arthritis Research UK-funded scientists at The University of Manchester have identified a new way in which genotyping can be used to predict disease outcomes among sufferers of rheumatoid arthritis.

29 Apr 2015

Lung cancer surgery patients at higher risk of developing venous thromboembolism

New evidence suggests that lung cancer surgery patients are at higher risk of developing venous thromboembolism, including deep vein thrombosis (DVT) and pulmonary embolism (PE), than previously thought, with elevated risks of complications or death. When thromboemboli occur, they may be asymptomatic or attributed to post-surgical pain or complications, and may reflect both the lung cancer itself as well as compromised lung function after surgery.

29 Apr 2015

One of the most important global healthcare studies of this generation reaches significant patient enrollment milestone

The TVC Imaging System is FDA-approved to identify lipid-core plaques that may cause heart attacks. Identification of such plaques would be a major step toward the development of percutaneous coronary intervention (PCI) as a means to prevent coronary events...

29 Apr 2015

Men undergoing circumcision may be at increased risk of infecting female partners with HIV

In the midst of an international campaign to slow the spread of HIV in sub-Saharan Africa, the World Health Organization recommends male circumcision (the surgical removal of foreskin from the penis) which reduces HIV acquisition by 50-60%.

29 Apr 2015

First new treatment authorised in a decade for advanced cervical cancer patients in the UK

The European Commission has licensed Avastin in combination with standard chemotherapy for the treatment of women with advanced cervical cancer. Until now, the treatment has been available ahead of licence to eligible patients in England via individual requests to the Cancer Drugs Fund (CDF).

28 Apr 2015

Supporting people with macular degeneration: an interview with Dennis Lewis, AMD Alliance International

Once depression sets in, it's very hard to combat. Combinations of medication and talking therapy can help deal with that, but it can be tough when people reach rock bottom and that certainly does happen with macular degeneration...

28 Apr 2015

Therapy News and Research

OncoGenex provides update on Phase 3 ENSPIRIT trial evaluating custirsen for treatment of NSCLC

Novel combination therapy shows promise in mouse models of advanced prostate cancer

Study finds that gene therapy can clip out genetic material associated with heart failure

Cytokine GM-CSF likely plays important role in MS

Adult survivors of preterm births at higher risk of developing COPD

Patients with traumatic brain injuries need effective cognitive neuroscience-based therapies

CANCER-ID consortium aims to set up standard procedures for clinical validation of blood-based biomarkers

Better interventions needed to improve outcomes in young breast cancer patients

TDF switch effective in Asian chronic HBV patients

Kidney damage unlikely with TDF monotherapy in chronic HBV patients

Patients with adefovir-resistant HBV benefit from TDF monotherapy

University of St. Augustine plans to bring Doctor of Physical Therapy program to Miami

Sangamo BioSciences to present data on ZFP Therapeutic platform at ASGCT meeting

UI orthopedics researchers working on injectable, bioactive gel that can repair cartilage damage

Scientists identify new way to predict disease outcomes in people with rheumatoid arthritis

Lung cancer surgery patients at higher risk of developing venous thromboembolism

One of the most important global healthcare studies of this generation reaches significant patient enrollment milestone

Men undergoing circumcision may be at increased risk of infecting female partners with HIV

First new treatment authorised in a decade for advanced cervical cancer patients in the UK

Supporting people with macular degeneration: an interview with Dennis Lewis, AMD Alliance International

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

Latest News