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New consortium aims to develop precision medicines for globally devastating diseases

An innovative new Consortium will act as a ‘match-making’ service between pharmaceutical companies and researchers in Cambridge with the aim of developing and studying precision medicines for some of the most globally devastating diseases.

29 Jul 2015

New polymer gel could help create swallowable devices for ultra-long drug delivery

Medical devices designed to reside in the stomach have a variety of applications, including prolonged drug delivery, electronic monitoring, and weight-loss intervention. However, these devices, often created with nondegradable elastic polymers, bear an inherent risk of intestinal obstruction as a result of accidental fracture or migration. As such, they are usually designed to remain in the stomach for a limited time.

29 Jul 2015

Europe has increasing prevalence of fungal resistance, warns ESCMID

The European Society of Clinical Microbiology and Infectious Disease – an organization that explores the risks and best practices in infectious disease – is imploring global healthcare professionals and bodies to take a more active role in the growing problem of fungal resistance.

28 Jul 2015

Champions Oncology's revenue increases 32% to $3.2 million in fourth quarter 2015

Champions Oncology, Inc., engaged in the development of advanced technology solutions and services to personalize the development and use of oncology drugs, today announced its financial results for the year ended April 30, 2015.

28 Jul 2015

Brazilian cardiovascular researcher receives Georg Forster Research Award

The cardiovascular researcher Professor Robson Augusto Souza dos Santos of the Federal University of Minas Gerais in Belo Horizonte, Brazil, has been awarded the Georg Forster Research Award of the Alexander von Humboldt Foundation.

28 Jul 2015

New technique improves survival time for glioblastoma patients by 50%

The rapid spread of a common and deadly brain tumor has been slowed down significantly in a mouse model by cutting off the way some cancer cells communicate, according to a team of researchers that includes UF Health faculty.

28 Jul 2015

Yale researchers confirm NF1 gene as major player in development of skin cancer

A multidisciplinary team at Yale, led by Yale Cancer Center members, has defined a subgroup of genetic mutations that are present in a significant number of melanoma skin cancer cases. Their findings shed light on an important mutation in this deadly disease, and may lead to more targeted anti-cancer therapies.

28 Jul 2015

Detailed, 3D image of malaria protein could help develop new antimalarial drugs

The first three-dimensional image capturing a critical malaria 'conductor' protein could lead to the development of a new class of antimalarial drugs.

28 Jul 2015

Regeneron, Sanofi to jointly advance new immuno-oncology treatment options for cancer patients

Regeneron Pharmaceuticals, Inc. and Sanofi have entered into a new global collaboration to discover, develop and commercialize new antibody cancer treatments in the emerging field of immuno-oncology.

28 Jul 2015

Research findings may provide new approach to treating male infertility

A team of researchers from the National University of Singapore's (NUS) Yong Loo Lin School of Medicine has demonstrated for the first time that hydrogen sulphide (H2S), when applied exogenously, could protect testicular germ cells, which are male reproductive cells, against heat-induced injury, which is one of the major causes of male infertility.

28 Jul 2015

FDA grants Fast Track Designation to TxCell’s Ovasave for treatment of Crohn’s disease

TxCell SA, a biotechnology company developing innovative, personalized cell-based immunotherapies using antigen specific regulatory T-cells for severe chronic inflammatory and autoimmune diseases, announces today that the United States Food and Drug Administration has granted Fast Track Designation to TxCell’s lead product Ovasave for the treatment of moderate to severe Crohn’s disease.

28 Jul 2015

Scientists uncover how CD68 protein acts as gateway for malaria parasite to enter the liver

Scientists uncover a port of liver entry for malaria parasites in a report published in The Journal of Experimental Medicine. If these results hold up in humans, drugs that target this entry protein might help prevent the spread of disease.

28 Jul 2015

Scientists develop exercise mimic molecule that could help treat type 2 diabetes and obesity

Scientists from the University of Southampton have developed a molecule that acts as an exercise mimic, which could potentially help treat type 2 diabetes and obesity.

28 Jul 2015

Research sheds light on new therapeutic options for acute lymphoblastic leukemia

In industrialized countries like in Europe, acute lymphoblastic leukemia is the most common form of cancer in children. An international research consortium lead by pediatric oncologists from the Universities of Zurich and Hannover has now succeeded in decoding a specific form of this leukemia, which is regarded as incurable, and in obtaining insights for new therapeutic possibilities.

28 Jul 2015

UMass Amherst toxicologist hopes US regulatory agency may acknowledge hormesis hypothesis soon

When environmental toxicologist Edward Calabrese in the School of Public Health and Health Sciences at the University of Massachusetts Amherst heard recently that the U.S. National Regulatory Commission has opened a new docket on proposed rule changes and standards for radiation protection, he felt it as "a vindication of my 30-year career, in many ways."

25 Jul 2015

Researchers show how genetic modification of mouse strains complicate biomedical research interpretation

Investigators affiliated with VIB and UGent recently achieved great success with a study involving biomedical research on mouse models.

25 Jul 2015

Trends, R&D progress, and predicted revenues in RNAi therapies

When will RNAi therapies reach the market? Visiongain's brand new report shows you potential revenues to 2025, assessing data, trends, opportunities and prospects there.

25 Jul 2015

Family members who avoid major medical decisions may suffer from PTSD

Family members who make major medical decisions for relatives in an intensive care unit (ICU) may suffer posttraumatic stress disorder (PTSD) if they cope by avoiding the situation, according to a new study by scientists at Case Western Reserve University's Frances Payne Bolton School of Nursing.

25 Jul 2015

Prostate cancer patients more likely to receive medical care matched to level of risk

After decades of overtreatment for low-risk prostate cancer and inadequate management of its more aggressive forms, patients are now more likely to receive medical care matched to level of risk, according to a study by researchers at UC San Francisco.

25 Jul 2015

New paper describes positive effects of CRAC channel inhibitors in animal models of acute pancreatitis

Researchers from CalciMedica, Inc. and the University of Liverpool today announced the publication of a paper describing positive effects of calcium release-activated calcium (CRAC) channel inhibitors in animal models of acute pancreatitis. The paper, titled "Inhibitors of ORAI1 prevent cytosolic calcium-associated injury of human pancreatic acinar cells and acute pancreatitis in 3 mouse models" appears in the August edition of the journal Gastroenterology.

25 Jul 2015

Drugs News and Research

New consortium aims to develop precision medicines for globally devastating diseases

New polymer gel could help create swallowable devices for ultra-long drug delivery

Europe has increasing prevalence of fungal resistance, warns ESCMID

Champions Oncology's revenue increases 32% to $3.2 million in fourth quarter 2015

Brazilian cardiovascular researcher receives Georg Forster Research Award

New technique improves survival time for glioblastoma patients by 50%

Yale researchers confirm NF1 gene as major player in development of skin cancer

Detailed, 3D image of malaria protein could help develop new antimalarial drugs

Regeneron, Sanofi to jointly advance new immuno-oncology treatment options for cancer patients

Research findings may provide new approach to treating male infertility

FDA grants Fast Track Designation to TxCell’s Ovasave for treatment of Crohn’s disease

Scientists uncover how CD68 protein acts as gateway for malaria parasite to enter the liver

Scientists develop exercise mimic molecule that could help treat type 2 diabetes and obesity

Research sheds light on new therapeutic options for acute lymphoblastic leukemia

UMass Amherst toxicologist hopes US regulatory agency may acknowledge hormesis hypothesis soon

Researchers show how genetic modification of mouse strains complicate biomedical research interpretation

Trends, R&D progress, and predicted revenues in RNAi therapies

Family members who avoid major medical decisions may suffer from PTSD

Prostate cancer patients more likely to receive medical care matched to level of risk

New paper describes positive effects of CRAC channel inhibitors in animal models of acute pancreatitis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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