Cell Death News and Research

RSS

Stony Brook researchers discover novel metabolic pathway of lipid ceramide involved in cell death

A collaborative Stony Brook University research team has discovered a novel metabolic pathway of the lipid ceramide, which is involved in cell death.

10 Mar 2017

Scientists pinpoint key biological mechanism that can prevent proliferation of insulin-producing cells

If you become resistant to insulin, a condition that is a precursor to type 2 diabetes, your body tries to compensate by producing more of the "beta" cells in the pancreas that produce the critical hormone.

9 Mar 2017

TSRI researchers develop new drug candidates to target prostate and triple negative breast cancers

Scientists on the Florida campus of The Scripps Research Institute (TSRI) have designed two new drug candidates to target prostate and triple negative breast cancers.

9 Mar 2017

Study shows that peripartum cardiomyopathy is not disease of the poor and occurs globally

Peripartum cardiomyopathy (PPCM) occurs globally and is not a disease of the poor, according to research published today in the European Journal of Heart Failure. Cases were reported from many countries for the first time.

8 Mar 2017

Inflammation acts as double-edge sword in regeneration, study reveals

Regeneration is an inherent property of life. However, the potential to regenerate differs across species: while fish and amphibians can re-grow appendages such as limbs, tails, and fins, mammals, including humans, cannot restore injured organs to their original shape and function.

7 Mar 2017

Neuroprotective compound could save brain cells during stroke, rat study shows

Researchers from the University of Iowa Carver College of Medicine and the University of Miami Miller School of Medicine have shown that a neuroprotective compound tested in rats provides two-pronged protection for brain cells during stroke and improves physical and cognitive outcomes in the treated animals.

2 Mar 2017

Metabolic vulnerability in triple-negative breast cancer cells may help quell chemotherapy resistance

A team of researchers led by Alex Toker of the Ludwig Center at Harvard has discovered a metabolic weakness in triple-negative breast cancer cells that may be exploited to quell their resistance to chemotherapy.

2 Mar 2017

Highly prevalent gene variants in African Americans contribute to kidney disease

African Americans have a heightened risk of developing chronic and end-stage kidney disease. This association has been attributed to two common genetic variants - named G1 and G2 -- in APOL1, a gene that codes for a human-specific protein.

1 Mar 2017

Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Researchers at Monash University and Peter MacCallum Cancer Centre have identified for the first time how a new class of epigenetic drug engages with the immune system to kill off cancer cells, offering powerful new pathways for enhanced blood cancer therapies.

1 Mar 2017

Biologists develop new way to inhibit cancer cell cleanup mechanism

The genomes of cancer cells--cells that do not obey signals to stop reproducing--are riddled with genetic mutations, causing them inadvertently to make many dysfunctional proteins.

28 Feb 2017

Research sheds new light on key factor involved in several diseases

New light on a key factor involved in diseases such as Parkinson's disease, gastric cancer and melanoma has been cast through latest University of Otago, New Zealand, research carried out in collaboration with Australian scientists.

28 Feb 2017

Scientists find link between p53 gene in African American women and breast cancer risk

Scientists at The Wistar Institute in collaboration with Roswell Park Cancer Institute found a significant association between a rare genetic variant of the p53 gene present in African American women and their risk of developing breast cancer in premenopausal age. The study was published online by the journal NPJ Breast Cancer.

27 Feb 2017

Researchers identify genetic variants that may contribute to schizophrenia

New research has identified sections of DNA associated with altered regulation of gene expression underlying schizophrenia.

27 Feb 2017

Huddersfield researchers discover cancer curing molecule that opens door for highly-effective treatment

SCIENTISTS at the University of Huddersfield are the first to arrive at a deep understanding of a molecule that destroys cancerous tumours without harming healthy cell tissue.

27 Feb 2017

New humanized model enables better characterization of Alzheimer's pathology

Cells behave differently when removed from their environments, just as cells that develop in cultures do not behave like cells in living creatures.

24 Feb 2017

NSAIDs could potentially be repurposed as life-saving treatment for sepsis, research suggests

A potentially life-saving treatment for sepsis has been under our noses for decades in the non-steroidal anti-inflammatory drugs most people have in their medicine cabinets, a new University of Colorado Boulder study suggests.

23 Feb 2017

Scientists discover potent trigger of inflammatory disease

Institute scientists have revealed a potent inflammatory molecule released by dying cells triggers inflammation during necroptosis, a recently described form of cell death linked to inflammatory disease.

22 Feb 2017

Scientists explore role of salt and immune system in raising blood pressure of females

Many of us have noted how our hands and feet swell after eating too much salt. Now scientists are exploring how high salt intake can also make cells throughout the body of females swell, rupture, dump their contents and die, triggering an immune reaction that contributes to chronic high blood pressure.

22 Feb 2017

Cocaine addiction may disrupt iron regulation in the brain, study finds

Cocaine addiction may affect how the body processes iron, leading to a build-up of the mineral in the brain, according to new research from the University of Cambridge.

21 Feb 2017

Cancer cells adapt nerve cell mechanisms to fuel aggressive tumor growth and spread

How we think and fall in love are controlled by lightning-fast electrochemical signals across synapses, the dynamic spaces between nerve cells. Until now, nobody knew that cancer cells can repurpose tools of neuronal communication to fuel aggressive tumor growth and spread.

21 Feb 2017

Cell Death News and Research

Stony Brook researchers discover novel metabolic pathway of lipid ceramide involved in cell death

Scientists pinpoint key biological mechanism that can prevent proliferation of insulin-producing cells

TSRI researchers develop new drug candidates to target prostate and triple negative breast cancers

Study shows that peripartum cardiomyopathy is not disease of the poor and occurs globally

Inflammation acts as double-edge sword in regeneration, study reveals

Neuroprotective compound could save brain cells during stroke, rat study shows

Metabolic vulnerability in triple-negative breast cancer cells may help quell chemotherapy resistance

Highly prevalent gene variants in African Americans contribute to kidney disease

Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Biologists develop new way to inhibit cancer cell cleanup mechanism

Research sheds new light on key factor involved in several diseases

Scientists find link between p53 gene in African American women and breast cancer risk

Researchers identify genetic variants that may contribute to schizophrenia

Huddersfield researchers discover cancer curing molecule that opens door for highly-effective treatment

New humanized model enables better characterization of Alzheimer's pathology

NSAIDs could potentially be repurposed as life-saving treatment for sepsis, research suggests

Scientists discover potent trigger of inflammatory disease

Scientists explore role of salt and immune system in raising blood pressure of females

Cocaine addiction may disrupt iron regulation in the brain, study finds

Cancer cells adapt nerve cell mechanisms to fuel aggressive tumor growth and spread

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics