Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Multi-disciplinary project receives £390,000 grant to discover genetic cause of epilepsy

The University of Liverpool has received a £390,000 grant from Medical Research Council to conduct research into how mutations in genes can cause epilepsy.

20 Feb 2017

Disappointing Merck drug news provides new blueprint for moving towards cure for Alzheimer's

The recent announcement that Merck is halting a Phase II/III study for a promising Alzheimer's treatment (verubecestat) was another setback in the continued and intensive effort to deliver an innovative therapy by 2020.

17 Feb 2017

UC San Diego researchers receive new grant to advance malaria research

An international research team, led by principal investigator Elizabeth A. Winzeler, PhD, professor in the pediatric division of host-microbe systems and therapeutics at University of California San Diego School of Medicine, and colleagues have received a three-year, $4.7 million supplemental grant from the Bill & Melinda Gates Foundation to advance their development of improved therapies for malaria eradication and elimination.

17 Feb 2017

Pittcon 2017 taking place in 2 weeks, will feature over 700 leading companies in the scientific community

The Pittcon 2017 Exposition, which takes place March 5-9 at McCormick Place in Chicago, Illinois, will include 770 exhibitors (count as of February 6, 2017) of which 122 are first time exhibitors. Leading companies will be displaying products and services used by the scientific community in industrial, academic, and government labs.

From Pittcon 17 Feb 2017

Carving a career in science

I was interested in a whole range of subjects, but the one that really grasped me from a young age was biology and, in particular, human biology. I was really fascinated with how the human body worked and I still am; that's something that has stayed with me.

15 Feb 2017

TSRI scientists receive $3.3 million NIH grant to create new breast cancer treatments

A pair of scientists from the Florida campus of The Scripps Research Institute have been awarded up to $3.3 million from the National Cancer Institute of the National Institutes of Health to create the next generation of breast cancer treatments for the thousands of patients whose current treatment options are limited.

14 Feb 2017

Osmium-based compound seen to target cancer cells from inside

Researchers have witnessed - for the first time - cancer cells being targeted and destroyed from the inside, by an organo-metal compound discovered by the University of Warwick.

13 Feb 2017

Integration of Genedata Screener with Nanion SyncroPatch 384PE can take APC experiments to new level

Genedata, a leading provider of advanced software solutions for drug discovery and life science research, today announced new automated patch clamp (APC) functionality in Genedata Screener for Ion Channel Screening and a Genedata Ready-to-Run integration with Nanion SyncroPatch 384PE.

From Nanion Technologies 3 Feb 2017

Virginia Tech researchers receive NIH grant to improve malaria drug

As long as parasites continue to mount resistance to malaria drugs, scientists will be faced with the task of developing new, improved pharmaceuticals.

3 Feb 2017

New study offers insights into how antidepressants work in the brain

When they work, antidepressant medications may take weeks or months to alleviate symptoms of depression.

2 Feb 2017

Review highlights how light-sensing bacterial protein's structure aids biomedical research

A light-sensing protein from a salt-loving, sulfur-forming microbe has proved key to developing methods essential to advanced drug discovery, understanding human vision and other biomedical applications.

1 Feb 2017

Faster Drug Discovery with NanoTemper Technologies

NanoTemper Technologies develops, manufactures, and markets highly innovative instrument and software solutions for biomolecular analytics. A reputation for excellent products and services has made them the partner of choice for thousands of researchers worldwide, across pharmaceutical, biotechnology, and academic settings.

From NanoTemper Technologies 31 Jan 2017

GUMC researchers describe lab technique to fill gaps in clinical care and research

Researchers who developed and tested a revolutionary laboratory technique that allows for the endless growth of normal and diseased cells in a laboratory are publicly sharing how the technique works.

28 Jan 2017

Researchers compile list of toxins and medicinal compounds produced by amphibian family

As human diseases become alarmingly antibiotic resistant, identification of new pharmaceuticals is critical.

28 Jan 2017

Scientists identify key 'survival gene' that reduces mutation rates in mycobacteria

Scientists have discovered a key 'survival gene' that prevents strains of tuberculosis (TB) from mutating into drug-resistant 'superbugs'.

28 Jan 2017

Pulmospheres could serve as personalized, predictive model for assessing effect of IPF drugs

Pulmospheres, three dimensional multicellular spheroids composed of lung cells from individual patients, were shown to be effective in predicting the efficacy of medications for idiopathic pulmonary fibrosis, according to findings from University of Alabama at Birmingham scientists presented today in JCI Insight, a journal of the American Society for Clinical Investigation.

27 Jan 2017

TSRI researchers develop first stable semisynthetic single-celled organism

Life’s genetic code has only ever contained four natural bases. These bases pair up to form two “base pairs”—the rungs of the DNA ladder—and they have simply been rearranged to create bacteria and butterflies, penguins and people. Four bases make up all life as we know it.

25 Jan 2017

Drug Discovery News and Research

Further Reading

Multi-disciplinary project receives £390,000 grant to discover genetic cause of epilepsy

Disappointing Merck drug news provides new blueprint for moving towards cure for Alzheimer's

UC San Diego researchers receive new grant to advance malaria research

Pittcon 2017 taking place in 2 weeks, will feature over 700 leading companies in the scientific community

Carving a career in science

TSRI scientists receive $3.3 million NIH grant to create new breast cancer treatments

Osmium-based compound seen to target cancer cells from inside

Integration of Genedata Screener with Nanion SyncroPatch 384PE can take APC experiments to new level

Virginia Tech researchers receive NIH grant to improve malaria drug

New study offers insights into how antidepressants work in the brain

Review highlights how light-sensing bacterial protein's structure aids biomedical research

Faster Drug Discovery with NanoTemper Technologies

GUMC researchers describe lab technique to fill gaps in clinical care and research

Researchers compile list of toxins and medicinal compounds produced by amphibian family

Scientists identify key 'survival gene' that reduces mutation rates in mycobacteria

Pulmospheres could serve as personalized, predictive model for assessing effect of IPF drugs

TSRI researchers develop first stable semisynthetic single-celled organism

Chemists show that synthetic nanoparticles can achieve structural complexity of biomolecules

Researchers find new way to quantify olfactory sensory neurons using PET radiotracer

TSRI scientists develop new method to enhance drug discovery and protein research

eBook: Essential guide to organoids in drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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Expanding access to NMR with the Fourier 80 Duo