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New project aims to improve the efficacy and safety of CAR T therapies for solid tumors

Partners in the international consortium CAR T-REX announce the awarding of a highly competitive EIC Pathfinder Open grant, following the positive evaluation of their project entitled 'CAR T Cells Rewired to Prevent EXhaustion in the Tumour Microenvironment'.

23 Jun 2023

Pangolin study uncovers novel strains of coronaviruses and raises concerns about origin

Researchers identify novel HKU4-related coronavirus in a pangolin single-cell sequencing dataset.

22 Jun 2023

Plant based compound peruvoside may be able to prevent up to 12 medically important viruses

Peruvoside, a plant-based compound that is commonly used to treat heart failure, has been discovered to be able to prevent up to 12 medically important viruses, all originating from different virus families.

22 Jun 2023

Alternative splicing in neurodegenerative disease and the promise of RNA-based therapeutic strategies

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA, plays an important role in molecular biology.

21 Jun 2023

Uncovering the hidden genetic connections behind COVID-19 and comorbidities

Researchers performed a protein diffusion network analysis using tissue-specific GRNs to identify predispositions to COVID-19.

21 Jun 2023

Phase I clinical study of TCR NK cell therapy for sarcoma expected to commence later this year

The University of Texas MD Anderson Cancer Center and Replay today announced that the Food & Drug Administration (FDA) has issued a 'safe to proceed' for the Investigational New Drug (IND) application for NY-ESO-1 TCR/IL-15 NK, an engineered T cell receptor natural killer (TCR NK) cell therapy for advanced synovial sarcoma and myxoid/round cell liposarcoma.

20 Jun 2023

Urban jungle: How city living may impact mental health

Researchers explore the effects of the urban environment on adult mental health.

19 Jun 2023

Battle against RSV: Computational design paves way for new polyvalent vaccine

Research focuses on the design of a multi-epitope polyvalent vaccine against Human Respiratory Syncytial Virus (RSV), a leading cause of lower respiratory tract infections. The study utilizes computational methods and immunoinformatics tools to predict potential vaccine candidates and their interactions with Toll-like receptors (TLRs).

19 Jun 2023

Scientists develop new technique to peer into the genome's spatial architecture

People who owned black-and-white television sets until the 1980s didn't know what they were missing until they got a color TV.

19 Jun 2023

New data demonstrates severe AMR among non-typhoidal Salmonella isolated from food in China

Announcing a new article publication for Zoonoses journal. Non-typhoidal Salmonella (NTS) is a major cause of human salmonellosis globally. Food animals are major NTS reservoirs.

19 Jun 2023

CDC raises alarm: poor vaccine coverage fuels surge in meningococcal disease among HIV-infected individuals

CDC presents preliminary data showing an increase in meningococcal disease among human immunodeficiency virus (HIV)-infected individuals.

19 Jun 2023

Could mutated blood cells hold the key to lower Alzheimer's risk?

Researchers tested whether clonal hematopoiesis of indeterminate potential (CHIP) status was associated with Alzheimer's disease.

19 Jun 2023

PacBio collaborates with Radboudumc to explore genetic causes of rare and genetic diseases

PacBio, a leading developer of high-quality, highly accurate sequencing solutions today announced a clinical research study with Radboud University Medical Center (Radboudumc) to explore genetic causes of rare and genetic diseases.

19 Jun 2023

MGI reveals latest updates at ESHG conference in Glasgow

MGI Tech Co., Ltd. ("MGI"), a company committed to building core tools and technology to lead life science, held a Corporate Satellite Meeting and revealed significant local partnerships at the ESHG Conference in Glasgow.

From MGI 16 Jun 2023

A framework of the recombination pathway for coronaviruses

Researchers explored the different aspects of the coronavirus recombination pathway.

16 Jun 2023

Study concludes a single intramuscular injection of adintrevimab provides prophylactic efficacy against COVID-19 without safety concerns

Researchers evaluated the prophylactic immune protection conferred by a single intramuscular injection of adintrevimab (ADG20) against symptomatic COVID-19.

16 Jun 2023

From COVID-19 to future threats: building a global genomic surveillance network

Researchers present a modular framework for global sustainable networks of viral genomic surveillance.

16 Jun 2023

Innovative method to map specific DNA markings could be used for early cancer detection

Researchers from the Perelman School of Medicine at the University of Pennsylvania have invented a new way to map specific DNA markings called 5-methylcytosine (5mC) which regulate gene expression and have key roles in health and disease.

15 Jun 2023

Sleep duration and quality may affect the risk for diabetes

Fewer than six hours or more than 10 hours of sleep, and poor quality of sleep are associated with a greater risk for diabetes, according to research being presented Thursday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

15 Jun 2023

COVID-19 susceptibility mechanism discovered using a newly created tool

Researchers have discovered a mechanism for COVID-19 susceptibility using a newly created tool. The tool, GASPACHO, captures dynamic changes in gene expression along the innate immune response, allowing researchers to identify genes and molecular pathways associated with disease risk that have previously been too complex to detect or interpret.

15 Jun 2023

Genome News and Research

New project aims to improve the efficacy and safety of CAR T therapies for solid tumors

Pangolin study uncovers novel strains of coronaviruses and raises concerns about origin

Plant based compound peruvoside may be able to prevent up to 12 medically important viruses

Alternative splicing in neurodegenerative disease and the promise of RNA-based therapeutic strategies

Uncovering the hidden genetic connections behind COVID-19 and comorbidities

Phase I clinical study of TCR NK cell therapy for sarcoma expected to commence later this year

Urban jungle: How city living may impact mental health

Battle against RSV: Computational design paves way for new polyvalent vaccine

Scientists develop new technique to peer into the genome's spatial architecture

New data demonstrates severe AMR among non-typhoidal Salmonella isolated from food in China

CDC raises alarm: poor vaccine coverage fuels surge in meningococcal disease among HIV-infected individuals

Could mutated blood cells hold the key to lower Alzheimer's risk?

PacBio collaborates with Radboudumc to explore genetic causes of rare and genetic diseases

MGI reveals latest updates at ESHG conference in Glasgow

A framework of the recombination pathway for coronaviruses

Study concludes a single intramuscular injection of adintrevimab provides prophylactic efficacy against COVID-19 without safety concerns

From COVID-19 to future threats: building a global genomic surveillance network

Innovative method to map specific DNA markings could be used for early cancer detection

Sleep duration and quality may affect the risk for diabetes

COVID-19 susceptibility mechanism discovered using a newly created tool

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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