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New study describes unique bioengineered tissue construct for modeling colorectal cancer

A new study describes a unique bioengineered tissue construct, or organoid, into which colorectal cancer cells are embedded, creating a model of the tumor and surrounding extracellular matrix.

6 Dec 2017

PET scans can predict prostate cancer patients’ response to salvage radiation treatment

For prostate cancer patients who have rising levels of PSA (a cancer indicator) even after radical prostatectomy, early treatment makes a difference.

5 Dec 2017

Study: Doctors may prescribe double the number of opioids than what patient needs after hysterectomy

Doctors may be prescribing nearly twice the number of opioids than what the average patient needs after a hysterectomy, a new study suggests.

4 Dec 2017

Researchers identify vulnerability for glioblastoma subtypes

Glioblastoma, the most common and aggressive form of brain cancer, typically fails to respond to treatment or rapidly becomes drug resistant.

1 Dec 2017

Researchers unlock genetic processes underlying cancer

For many, breast cancer is more than just a disease – it's personal. One in eight women will be diagnosed with breast cancer at some point in their lives. But through new discoveries at the genetic level, the personal nature of cancer will eventually be what helps to beat it.

29 Nov 2017

Easy-to-use omics toolkit sets the stage for new era of biology and precision medicine

Most complex diseases, such as obesity, longevity, and diabetes, are largely influenced by genetic factors. But at the same time, they are also modulated by environmental stimuli, such as diet and physical activity.

29 Nov 2017

UT Southwestern researchers take early step toward personalized care for breast cancer

UT Southwestern Medical Center researchers have developed a method to map protein changes that occur in different subtypes of breast cancer cells in response to DNA damage from a new class of chemotherapy drugs.

29 Nov 2017

Digital image of the retina provides enormous information about patients' general health

Personalized medicine or "precision medicine" is the most significant trend in 21st century medicine. "It's all about the right treatment for the right patient at the right time," says Ursula Schmidt-Erfurth, Head of MedUni Vienna's Department of Ophthalmology and Optometry.

28 Nov 2017

New molecular taxonomy may lead to precision-medicine treatments for hair disorders

Two decades ago, oncologists realized that molecular biologists could see medically important differences between tumors that looked identical to pathologists.

28 Nov 2017

Researchers discover critical trigger for leading form of vision loss

In a major step forward in the battle against macular degeneration, the leading cause of vision loss among the elderly, researchers at the University of Virginia School of Medicine have discovered a critical trigger for the damaging inflammation that ultimately robs millions of their sight.

27 Nov 2017

Metabolites significantly affected in chronic kidney disease, study finds

Chronic kidney disease (CKD) affects 1 in 7 people in the United States, according to the U.S. National Institute of Diabetes & Digestive & Kidney Diseases.

22 Nov 2017

Simple test could help predict best treatment for cystic fibrosis patients

Several cutting-edge treatments have become available in recent years to correct the debilitating chronic lung congestion associated with cystic fibrosis. While the new drugs are life-changing for some patients, they do not work for everyone.

21 Nov 2017

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

D. Brent Polk, MD, AGAF, an investigator at Children's Hospital Los Angeles, has been awarded $1.5 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the NIH for the study of tumor necrosis factor (TNF) and its role in inflammatory bowel disease (IBD).

20 Nov 2017

First-of-its-kind study combines smoking cessation with personalized medicine

A simple blood test is allowing Vanderbilt University Medical Cente researchers to determine which patients should be prescribed varenicline (Chantix) to stop smoking and which patients could do just as well, and avoid side effects, by using a nicotine patch.

20 Nov 2017

Researchers identify three specific molecules that accurately indicate pre-diabetes

Researchers from the University of Sydney's Charles Perkins Centre have identified three specific molecules that accurately indicate insulin resistance, or pre-diabetes - a major predictor of metabolic syndrome, the collection of medical conditions that include abdominal obesity, high blood pressure and high blood sugar levels.

20 Nov 2017

New technique holds promise to screen cancer cells for drug susceptibility

Doctors have many drugs available to treat multiple myeloma, a type of blood cancer. However, there is no way to predict, by genetic markers or other means, how a patient will respond to a particular drug. This can lead to months of treatment with a drug that isn't working.

20 Nov 2017

Research highlights potential solutions to fill policy gaps and advance breast cancer control in Asia

Education conducted by civil society can play an important role in filling breast cancer policy gaps and advancing cancer control, including advanced breast cancer, researchers report at the ESMO Asia 2017 Congress.

20 Nov 2017

Researchers map first-ever proteome of healthy human heart

A healthy heart beats about two billion times during a lifetime – thanks to the interplay of more than 10,000 proteins. Researchers from the Max Planck Institute of Biochemistry and the German Heart Centre at the Technical University of Munich have now determined which and how many individual proteins are present in each type of cell that occurs in the heart.

17 Nov 2017

Study explores reasons for underrepresentation of minorities in genetic cancer research

Socio-cultural and clinical factors as well as healthcare processes were important drivers of a woman's willingness to provide saliva specimens for future cancer research.

16 Nov 2017

Genetic diversity of tumor tissues can be barrier to precision medicine in gastric and esophageal cancers

A new study focused on describing genetic variations within a primary tumor, differences between the primary and a metastatic branch of that tumor, and additional diversity found in tumor DNA in the blood stream could help physicians make better treatment choices for patients with gastric and esophageal adenocarcinoma.

15 Nov 2017

Precision Medicine News and Research

New study describes unique bioengineered tissue construct for modeling colorectal cancer

PET scans can predict prostate cancer patients’ response to salvage radiation treatment

Study: Doctors may prescribe double the number of opioids than what patient needs after hysterectomy

Researchers identify vulnerability for glioblastoma subtypes

Researchers unlock genetic processes underlying cancer

Easy-to-use omics toolkit sets the stage for new era of biology and precision medicine

UT Southwestern researchers take early step toward personalized care for breast cancer

Digital image of the retina provides enormous information about patients' general health

New molecular taxonomy may lead to precision-medicine treatments for hair disorders

Researchers discover critical trigger for leading form of vision loss

Metabolites significantly affected in chronic kidney disease, study finds

Simple test could help predict best treatment for cystic fibrosis patients

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

First-of-its-kind study combines smoking cessation with personalized medicine

Researchers identify three specific molecules that accurately indicate pre-diabetes

New technique holds promise to screen cancer cells for drug susceptibility

Research highlights potential solutions to fill policy gaps and advance breast cancer control in Asia

Researchers map first-ever proteome of healthy human heart

Study explores reasons for underrepresentation of minorities in genetic cancer research

Genetic diversity of tumor tissues can be barrier to precision medicine in gastric and esophageal cancers

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